Zobrazeno 1 - 10
of 50
pro vyhledávání: '"Jennifer Y. Tan"'
Autor:
Nikita Sushentsev, Gregory Hamm, Lucy Flint, Daniel Birtles, Aleksandr Zakirov, Jack Richings, Stephanie Ling, Jennifer Y. Tan, Mary A. McLean, Vinay Ayyappan, Ines Horvat Menih, Cara Brodie, Jodi L. Miller, Ian G. Mills, Vincent J. Gnanapragasam, Anne Y. Warren, Simon T. Barry, Richard J. A. Goodwin, Tristan Barrett, Ferdia A. Gallagher
Publikováno v:
Nature Communications, Vol 15, Iss 1, Pp 1-22 (2024)
Abstract Hyperpolarised magnetic resonance imaging (HP-13C-MRI) has shown promise as a clinical tool for detecting and characterising prostate cancer. Here we use a range of spatially resolved histological techniques to identify the biological mechan
Externí odkaz:
https://doaj.org/article/5d269719830146bfb19310f180c8fbe9
Autor:
Elizabeth A Coe, Jennifer Y Tan, Michael Shapiro, Pakavarin Louphrasitthiphol, Andrew R Bassett, Ana C Marques, Colin R Goding, Keith W Vance
Publikováno v:
PLoS Genetics, Vol 15, Iss 12, p e1008501 (2019)
The MITF and SOX10 transcription factors regulate the expression of genes important for melanoma proliferation, invasion and metastasis. Despite growing evidence of the contribution of long noncoding RNAs (lncRNAs) in cancer, including melanoma, thei
Externí odkaz:
https://doaj.org/article/b5750b702ac44908b4d02ca83fd30566
Autor:
Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting
Publikováno v:
eLife, Vol 8 (2019)
Externí odkaz:
https://doaj.org/article/c93c5ec864b44cedab0bcd20167ad15a
Autor:
Tamara M Sirey, Kenny Roberts, Wilfried Haerty, Oscar Bedoya-Reina, Sebastian Rogatti-Granados, Jennifer Y Tan, Nick Li, Lisa C Heather, Roderick N Carter, Sarah Cooper, Andrew J Finch, Jimi Wills, Nicholas M Morton, Ana Claudia Marques, Chris P Ponting
Publikováno v:
eLife, Vol 8 (2019)
To generate energy efficiently, the cell is uniquely challenged to co-ordinate the abundance of electron transport chain protein subunits expressed from both nuclear and mitochondrial genomes. How an effective stoichiometry of this many constituent s
Externí odkaz:
https://doaj.org/article/7203b3e44ab34c76a17f006cfd21d380
Autor:
Christian Widmann, Jennifer Y. Tan, Claudiane Guay, Ana C. Marques, Romano Regazzi, Sabine Rütti, D. R. Laybutt, Gilles Dubuis, Baroj Abdulkarim
Publikováno v:
Scientific Reports, Vol 10, Iss 1, Pp 1-9 (2020)
Scientific reports, vol. 10, no. 1, pp. 6413
Scientific Reports
Scientific reports, vol. 10, no. 1, pp. 6413
Scientific Reports
Long non-coding RNAs (lncRNAs) contribute to diverse cellular functions and the dysregulation of their expression or function can contribute to diseases, including diabetes. The contributions of lncRNAs to β-cell development, function and survival h
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::87a83bd0fe2496fca6c6a944e89f772a
http://link.springer.com/article/10.1038/s41598-020-62969-x
http://link.springer.com/article/10.1038/s41598-020-62969-x
Autor:
Adriano Biasini, Constance Ciaudo, Harry Wischnewski, Jennifer Y. Tan, Stefano de Pretis, René Dreos, Rajika Arora, Ana C. Marques, Mattia Pelizzola, Baroj Abdulkarim
Publikováno v:
The EMBO Journal, 40 (3)
The EMBO Journal
The EMBO Journal
Post‐transcriptional repression of gene expression by miRNAs occurs through transcript destabilization or translation inhibition. mRNA decay is known to account for most miRNA‐dependent repression. However, because transcript decay occurs co‐tr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8aed93dab34315fed5f0f5befc617d5
https://hdl.handle.net/20.500.11850/461847
https://hdl.handle.net/20.500.11850/461847
Autor:
Marc W. Schmid, Tuncay Baubec, Raffaella Santoro, Damian Dalcher, Ana C. Marques, Rostyslav Kuzyakiv, Stefan Butz, Valerio Bianchi, Jennifer Y. Tan, Cristiana Bersaglieri, Marcin Roganowicz, Rodrigo Peña-Hernández, Stefan Zeyen, Eva Vollenweider
Publikováno v:
The EMBO Journal
Chromosomes have an intrinsic tendency to segregate into compartments, forming long‐distance contacts between loci of similar chromatin states. How genome compartmentalization is regulated remains elusive. Here, comparison of mouse ground‐state e
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b1755360ffa7f513ddf732988cf559a0
http://europepmc.org/articles/PMC7705451
http://europepmc.org/articles/PMC7705451
Determining which genes are targeted by miRNAs is crucial to elucidate their contributions to diverse biological processes in health and disease. Most miRNA target prediction tools rely on the identification of complementary regions between transcrip
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::975ce9c9d41312a22e1d37cb962a751b
https://doi.org/10.1101/2020.07.07.191023
https://doi.org/10.1101/2020.07.07.191023
Autor:
Tuncay Baubec, Ana C. Marques, Gustavo A. Ruiz Buendía, Flavia Marzetta, Marion Leleu, Ludovica Vanzan, Ioannis Xenarios, Victor Ythier, Rabih Murr, Vincent Dion, Emma L. Randall, Jennifer Y. Tan
Publikováno v:
Science Advances
Science advances, vol. 6, no. 27, pp. eaaz4012
Science advances, vol. 6, no. 27, pp. eaaz4012
Unexpectedly, the molecular pathogenesis of expanded CAG/CTG diseases does not include changes in 3D chromatin conformation.
Expanded CAG/CTG repeats underlie 13 neurological disorders, including myotonic dystrophy type 1 (DM1) and Huntington’
Expanded CAG/CTG repeats underlie 13 neurological disorders, including myotonic dystrophy type 1 (DM1) and Huntington’
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::369e9f1966f82516abe6c54b51cd784f
http://europepmc.org/articles/PMC7334000
http://europepmc.org/articles/PMC7334000