Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer Y Barr"'
Autor:
Pamela K Geyer, Darren S Hoffmann, Jennifer Y Barr, Heather A Widmayer, Christine M Blaumueller
Publikováno v:
PLoS ONE, Vol 19, Iss 4, p e0301480 (2024)
Strong scientific writing skills are the foundation of a successful research career and require training and practice. Although these skills are critical for completing a PhD, most students receive little formal writing instruction prior to joining a
Externí odkaz:
https://doaj.org/article/8219648aa75a4f8ebcf89201bd9f74c9
Autor:
Ashley E. Ciecko, Bardees Foda, Jennifer Y. Barr, Sheela Ramanathan, Mark A. Atkinson, David V. Serreze, Aron M. Geurts, Scott M. Lieberman, Yi-Guang Chen
Publikováno v:
Cell Reports, Vol 29, Iss 10, Pp 3073-3086.e5 (2019)
Summary: Human genetic studies implicate interleukin-27 (IL-27) in the pathogenesis of type 1 diabetes (T1D), but the underlying mechanisms remain largely unexplored. To further define the role of IL-27 in T1D, we generated non-obese diabetic (NOD) m
Externí odkaz:
https://doaj.org/article/3fc24c0010584feaa74f430e920e1248
Publikováno v:
Immunological investigations. 51(6)
The nonreceptor tyrosine kinase ITK is a key component of the T cell receptor (TCR) signaling pathway and is required for cytokine production by CD4+ T cells that have differentiated into Th2 cells. Structural and biochemical studies suggest that con
Publikováno v:
Immunology and cell biology
Sjögren syndrome is an autoimmune disease characterized by targeted destruction of the lacrimal and salivary glands resulting in symptoms of severe ocular and oral dryness. Despite its prevalence, the mechanisms driving autoimmune manifestations are
Autor:
Helen E. Thomas, Thomas C. Brodnicki, David A. Sullivan, Scott M. Lieberman, Jennifer Y. Barr, Yury Chaly
Publikováno v:
International Journal of Molecular Sciences
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3259 (2018)
Volume 19
Issue 10
International Journal of Molecular Sciences, Vol 19, Iss 10, p 3259 (2018)
Nonobese diabetic (NOD) mice spontaneously develop lacrimal and salivary gland autoimmunity similar to human Sjö
gren syndrome. In both humans and NOD mice, the early immune response that drives T-cell infiltration into lacrimal and salivary
gren syndrome. In both humans and NOD mice, the early immune response that drives T-cell infiltration into lacrimal and salivary
Publikováno v:
Immunology. 155(2)
Immune cell-mediated destruction of salivary glands is a hallmark feature of Sjogren syndrome. Similar to the female predominance in humans, female non-obese diabetic (NOD) mice develop spontaneous salivary gland autoimmunity. However, in both humans
Autor:
Scott M. Lieberman, Aron M. Geurts, Yi-Guang Chen, Jennifer Y. Barr, Bardees M. Foda, Sheela Ramanathan, David V. Serreze, Mark A. Atkinson, Ashley E. Ciecko
Publikováno v:
Cell reports
Cell Reports, Vol 29, Iss 10, Pp 3073-3086.e5 (2019)
Cell Reports, Vol 29, Iss 10, Pp 3073-3086.e5 (2019)
SUMMARY Human genetic studies implicate interleukin-27 (IL-27) in the pathogenesis of type 1 diabetes (T1D), but the underlying mechanisms remain largely unexplored. To further define the role of IL-27 in T1D, we generated non-obese diabetic (NOD) mi
Publikováno v:
Journal of immunology (Baltimore, Md. : 1950). 198(10)
B cell development in Justy mutant mice is blocked due to a precursor mRNA splicing defect that depletes the protein GON4-like (GON4L) in B cell progenitors. Genetic and biochemical studies have suggested that GON4L is a transcriptional regulator tha
Autor:
Hai-Hui Xue, John D. Colgan, Khanh L. Duong, Snehalata Jena, Satyabrata Das, Eun-Mi Kim, Nicolas Zavazava, Jennifer Y. Barr, Dana N. Levasseur, Shuyang Yu
Publikováno v:
Experimental hematology. 42(9)
The development of a hematopoietic reporter is crucial for determining the fate of lineages derived from cell-based therapies. A marking system will enable safer embryonic stem and induced pluripotent stem cell-based derivation of blood lineages and
Autor:
Jennifer Y. Barr, David G. Motto
Publikováno v:
Von Willebrand Disease: Basic and Clinical Aspects
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::89fc1b78ae8c03043365fe8b29044f2c
https://doi.org/10.1002/9781444329926.ch4
https://doi.org/10.1002/9781444329926.ch4