Zobrazeno 1 - 10
of 218
pro vyhledávání: '"Jennifer Willis"'
Autor:
Ewan A. Ross, Lesley-Anne Turner, Hannah Donnelly, Anwer Saeed, Monica P. Tsimbouri, Karl V. Burgess, Gavin Blackburn, Vineetha Jayawarna, Yinbo Xiao, Mariana A. G. Oliva, Jennifer Willis, Jaspreet Bansal, Paul Reynolds, Julia A. Wells, Joanne Mountford, Massimo Vassalli, Nikolaj Gadegaard, Richard O. C. Oreffo, Manuel Salmeron-Sanchez, Matthew J. Dalby
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-16 (2023)
Mesenchymal Stromal Cells are hard to expand whilst retaining immunomodulatory properties due to spontaneous differentiation and ageing in culture. Here, the authors describe a mechanotransductive link between metabolism and functional activity and i
Externí odkaz:
https://doaj.org/article/3492f3b33d7a422a8a602e5982a536a0
Autor:
Stefanie W. Benoit, Tsuyoshi Fukuda, Katherine VandenHeuvel, David Witte, Christine Fuller, Jennifer Willis, Bradley P. Dixon, Keri A. Drake
Publikováno v:
Frontiers in Pediatrics, Vol 10 (2022)
BackgroundAtypical hemolytic uremic syndrome (aHUS) is an ultra-rare orphan disease caused by dysregulated complement activation resulting in thrombotic microangiopathy. Although complement-mediated endothelial injury predominantly affects the renal
Externí odkaz:
https://doaj.org/article/27c216cb11a0446faef5b77a8d198b03
Autor:
Maria Teresa Eyzaguirre Pellon, Ann Marie Walsh, Jennifer Willis, Judith Forbes, Jensyn Cone Sullivan
Publikováno v:
Transfusion. 62:1697-1698
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::abe4eab6cf0d99df3ed2832a86540bf3
https://doi.org/10.1111/trf.17046
https://doi.org/10.1111/trf.17046
Autor:
Sonia N. Young Pt, Dpt, EdD, Ncs, BS Jennifer Willis Ba, Krisstal D. Clayton, C. Nicole Clark Pt, Dpt, Csrs, Neale R. Chumbler
Publikováno v:
Physiotherapy theory and practice. 37(2)
Background: Stroke can result in disabling impairments, affecting functional mobility, balance, and gait. Individualized in-patient rehabilitation interventions improve balance and gait in patients with stroke. Rhythmic pairing of personally-selected
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0cd9319a53fe3f5b50df3ce2c5998336
https://pubmed.ncbi.nlm.nih.gov/31204555
https://pubmed.ncbi.nlm.nih.gov/31204555
Autor:
Catherine Ritchie, Lucy Barker, Matthew Bm Thomas, Jodie Manini, Elisabeth Willard, Jennifer Willis, Zarin Brown, Edward Charles Hall, Gareth Williams, Ryan West, Steven J. Charlton, David Andrew Sandham, Lyndon Nigel Brown, Simon J. Watson, Janet Maas, Devnandan Chatterjee, David A. Sykes, Nicholas Duggan, Katharine L. Turner, Gerald Dubois, David C. Budd, Bindi Sohal, Rowan Stringer, Rachael Profit, Darren Riddy, Duncan Shaw, Julia Hatto, Brian Cox
Further optimization of an initial DP2 receptor antagonist clinical candidate NVP-QAV680 led to the discovery of a follow-up molecule 2-(2-methyl-1-(4-(methylsulfonyl)-2-(trifluoromethyl)benzyl)-1H-pyrrolo[2,3-b]pyridin-3-yl)acetic acid (compound 11,
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e65a3f67567222f76078480d2373e99e
https://europepmc.org/articles/PMC5430394/
https://europepmc.org/articles/PMC5430394/
Autor:
Brian Cox, David C. Budd, Anna King, Gareth Williams, Nicholas Duggan, Rowan Stringer, Marcus Furegati, Alfred Schmidt, Josef G. Meingassner, Kamlesh Bala, Brian Everatt, Katharine L. Turner, Jennifer Simmons, Cerys Docx, Catherine Leblanc, Gerald Dubois, Frank Kalthoff, Caroline Wilson, Lucy Barker, Karen England, Nicola Arnold, John Westwick, Edward Charles Hall, Bindi Sohal, Jennifer Willis, Heinrich Aschauer, David Andrew Sandham, Rachael Profit, Zarin Brown, Lyndon Nigel Brown, Simon J. Watson, Jodie Manini, Christoph Walker, Matthew Thomas
Publikováno v:
Bioorganic & Medicinal Chemistry. 21:6582-6591
Optimization of a 7-azaindole-3-acetic acid CRTh2 receptor antagonist chemotype derived from high throughput screening furnished a highly selective compound NVP-QAV680 with low nM functional potency for inhibition of CRTh2 driven human eosinophil and
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1cc63a5fbb90947c1f906a4739b943b4
https://doi.org/10.1016/j.bmc.2013.08.025
https://doi.org/10.1016/j.bmc.2013.08.025
Publikováno v:
Journal of Pharmacy Practice and Research. 37:200-203
Background: Penicillins are used first-line for many infections and are commonly associated with adverse drug responses. Pharmacists can take a detailed adverse drug response history and provide such information to prescribers. Aim: To investigate an
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::44fb4c174142bd8bea9e5473237a336d
https://doi.org/10.1002/j.2055-2335.2007.tb00744.x
https://doi.org/10.1002/j.2055-2335.2007.tb00744.x
Publikováno v:
Fertility and Sterility. 88:737-740
The purpose of our study was to analyze the relationship of leukocytospermia to sperm DNA damage as assessed by the DNA integrity assay. Results indicate that leukocytospermia has a significant negative effect on the standard semen parameters of conc
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a05cbaa1c369e75d8680563ff4682d12
https://doi.org/10.1016/j.fertnstert.2006.11.132
https://doi.org/10.1016/j.fertnstert.2006.11.132