Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jennifer Wellman McDonnell"'
Autor:
Arkady Lyubarsky, Jean Bennett, Xiaosong Zhu, Maureen G. Maguire, Eric A. Pierce, Enrico Maria Surace, Kathleen A. Marshall, Barbara A. Konkle, Sandro Banfi, L. F. Dell'Osso, Jeannette L. Bennicelli, Jonathan B. Jacobs, Edwin M. Stone, J. Fraser Wright, Richard W. Hertle, Kenneth S. Shindler, Edward N. Pugh, Nicholas J. Volpe, Jennifer Wellman McDonnell, Katherine A. High, Junwei Sun, Valder R. Arruda, Francesco Testa, Albert M. Maguire, Jian Xing Ma, Alberto Auricchio, Federico Mingozzi, Bernd Hauck, Olga Zelenaia, T. Michael Redmond, Francesca Simonelli, Settimio Rossi
Publikováno v:
New England Journal of Medicine. 358:2240-2248
S um m a r y Leber's congenital amaurosis (LCA) is a group of inherited blinding diseases with onset during childhood. One form of the disease, LCA2, is caused by mutations in the retinal pigment epithelium-specific 65-kDa protein gene (RPE65). We in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4bedee9d5016d2cd789444b7de1fd948
https://doi.org/10.1056/nejmoa0802315
https://doi.org/10.1056/nejmoa0802315
Autor:
Pete Smith, Joseph Prado, Glenn F. Pierce, Floro Cataniag, Shangzhen Zhou, Katherine A. High, Alex Tai, Jac Luna, Jennifer Wellman McDonnell, J. Fraser Wright, Guang Qu, Jurg M. Sommer, Jingmin Zhou, Peter Colosi, Bernd Hauck, Jennifer Bahr-Davidson
Publikováno v:
Journal of Virological Methods. 140:183-192
Adeno-associated virus (AAV) empty capsids typically co-purify with genome containing AAV2 vectors purified by column chromatography. This study describes a method to remove empty capsids from genome containing vector particles by anion exchange chro
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8b1d912561265ebd70ac0de886cf63f4
https://doi.org/10.1016/j.jviromet.2006.11.019
https://doi.org/10.1016/j.jviromet.2006.11.019
Autor:
Pete Smith, Michael A. Lochrie, Peter Colosi, Kris Jones, Gwen Tatsuno, Alejandra E. Arbetman, Shang Zhen Zhou, Cheryl Pater, Michiko Kachi, Glenn F. Pierce, Jennifer Wellman McDonnell, Peter A. Campochiaro, Shu Kachi
Publikováno v:
Virology. 353:68-82
Using polymerase chain reactions and genome walking strategies, adeno-associated virus (AAV)-like capsid genes were isolated from rat and mouse liver genomic DNA, where they are present at
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1a4ba283d11c97687a5ef5138d385ee8
https://doi.org/10.1016/j.virol.2006.05.023
https://doi.org/10.1016/j.virol.2006.05.023
Autor:
Glenn F. Pierce, Shangzhen Zhou, Michael A. Lochrie, Jennifer Wellman McDonnell, B Christie, Peter Colosi, Gwen P. Tatsuno, Richard T. Surosky
Publikováno v:
Journal of Virology. 80:821-834
Mutations were made at 64 positions on the external surface of the adeno-associated virus type 2 (AAV-2) capsid in regions expected to bind antibodies. The 127 mutations included 57 single alanine substitutions, 41 single nonalanine substitutions, 27
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::816e047dab815c9762633b5d30789f1b
https://doi.org/10.1128/jvi.80.2.821-834.2006
https://doi.org/10.1128/jvi.80.2.821-834.2006
Autor:
Jeannette L. Bennicelli, Carmela Acerra, Sandro Banfi, Settimio Rossi, Carmela Ziviello, Kenneth S. Shindler, T. Michael Redmond, Federico Mingozzi, Kathleen A. Marshall, Francesca Simonelli, Xiaosong Zhu, Enrico Maria Surace, Eric A. Pierce, Katherine A. High, Junwei Sun, Albert M. Maguire, Jennifer Wellman McDonnell, Francesco Testa, J. Fraser Wright, Alberto Auricchio, Gui-Shuang Ying, Jean Bennett
Publikováno v:
Molecular Therapy
Molecular Therapy; Vol 18
Molecular Therapy; Vol 18
The safety and efficacy of gene therapy for inherited retinal diseases is being tested in humans affected with Leber's congenital amaurosis (LCA), an autosomal recessive blinding disease. Three independent studies have provided evidence that the subr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::298c97d708abc418927ba2d6165559ed
https://pubmed.ncbi.nlm.nih.gov/20195259
https://pubmed.ncbi.nlm.nih.gov/20195259