Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jennifer Vuong"'
Autor:
Matthew W McClure, Elina Berliba, Tengiz Tsertsvadze, Adrian Streinu-Cercel, Leen Vijgen, Béatrice Astruc, Alain Patat, Christopher Westland, Sushmita Chanda, Qingling Zhang, Thomas N Kakuda, Jennifer Vuong, Nick Khorlin, Leonid Beigelman, Lawrence M Blatt, John Fry
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204974 (2018)
BACKGROUND:The nucleotide analog AL-335 is a pangenotypic hepatitis C virus (HCV) nonstructural protein (NS)5B inhibitor being evaluated as treatment for chronic HCV infection. METHODS:This three-part randomized, double-blind study evaluated the safe
Externí odkaz:
https://doaj.org/article/734ab2d56f1a434cbd65736ecb72aa86
Autor:
Sushmita Mukherjee Chanda, Christian Schwabe, E.J. Gane, Megha Patel, Oliver Lenz, Jan Snoeys, Jeysen Yogaratnam, Christopher Westland, Jennifer Vuong, Willem Talloen, Thomas N. Kakuda, Pieter Van Remoortere, John Fry
Publikováno v:
Antiviral therapy. 26(1-2)
Background Pharmacokinetics and safety of JNJ-64530440, a hepatitis B virus capsid assembly modulator producing normal empty capsids (CAM-N), in healthy volunteers were evaluated. Methods This Phase I study (NCT03439488) was a double-blind, randomise
Autor:
Gwendoline Poizat, Marie-Claude Homery, David B. Smith, John Fry, Laure Viguerie, Christopher Westland, Alain Patat, Caroline Denot, Qingling Zhang, Jennifer Vuong, Matthew W. McClure, Sushmita Mukherjee Chanda, James Hui, David Apelian, Thomas N. Kakuda
Publikováno v:
Pharmacology Research & Perspectives
This Phase I, open‐label, two‐group, fixed‐sequence study evaluated the pharmacokinetics and safety of AL‐335, odalasvir, and simeprevir in healthy subjects. Group 1 (n = 16) received AL‐335 800 mg once daily (QD) (days 1‐3, 11‐13, and
Autor:
Elina Berliba, Alain Patat, Jennifer Vuong, Béatrice Astruc, Matthew W. McClure, John Fry, Leen Vijgen, Thomas N. Kakuda, Lawrence M. Blatt, Tengiz Tsertsvadze, Nick Khorlin, Adrian Streinu-Cercel, Sushmita Mukherjee Chanda, Christopher Westland, Qingling Zhang, Leonid Beigelman
Publikováno v:
PLoS ONE, Vol 13, Iss 10, p e0204974 (2018)
PLoS ONE
PLoS ONE
Background The nucleotide analog AL-335 is a pangenotypic hepatitis C virus (HCV) nonstructural protein (NS)5B inhibitor being evaluated as treatment for chronic HCV infection. Methods This three-part randomized, double-blind study evaluated the safe
Publikováno v:
American Journal of Hematology. 89:671-677
Body mass index (BMI), the prevalent indicator of obesity, is not easily grasped by patients nor physicians. Waist circumference (WC) is correlated to obesity, is better understood and has a stronger relationship to the metabolic syndrome. We compile
Publikováno v:
Epilepsia. 52:2285-2292
Summary Purpose: Neural reorganization and interictal behavioral anomalies have been documented in people with epilepsy and in animal seizure models. Alterations in behavior could be due to somatosensory dysfunction. This study was designed to determ
Publikováno v:
Journal of Neuroscience Methods. 196:60-69
Intracortical microstimulation (ICMS) is a technique that was developed to derive movement representations (motor maps) of the motor cortex, and was originally used in cats and the capuchin monkey. In more modern experiments, ICMS has been used in ra
Publikováno v:
The Annals of pharmacotherapy. 48(4)
Background: Alkalinized Viokase pancreatic enzyme tablets restored patency to 71.9% of occluded Dobhoff tubes in a prospective study. After removal of Viokase tablets from the US market, the hospital protocol for unclogging enteral feeding tubes was
Publikováno v:
Journal of neurophysiology. 108(5)
While a substantial literature demonstrates the effect of differential experience on development of mammalian sensory cortices and plasticity of adult motor cortex, characterization of differential experience on the functional development of motor co
Publikováno v:
Epilepsia. 52(12)
Neural reorganization and interictal behavioral anomalies have been documented in people with epilepsy and in animal seizure models. Alterations in behavior could be due to somatosensory dysfunction. This study was designed to determine whether seizu