Výsledky vyhledávání - "Jennifer VanEyk"

Abstract 422: Placental Cdx2 Cells Regenerate Injured Myocardium

Autor: Sangeetha Vadakke-Madathil, Gina LaRocca, Jesse Yoon, Koen Raedschelders, Joseph Tripodi, Jennifer VanEyk, Vesna Najfeld, Hina W. Chaudhry

Publikováno v: Circulation Research. 125

The limited regeneration of adult mammalian heart has prompted the need to recognize novel strategies that can restore contractile function in heart disease. However, in cell-based therapies the lack of an appropriate cell-type that can differentiate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::526339dedf9631ca9ef0f74c21b6d4cb
https://doi.org/10.1161/res.125.suppl_1.422

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Abstract 361: Deacetylation of Lc3 Drives Autophagy and Proteome Remodeling in Skeletal Muscle During Oncometabolic Stress

Autor: Roberta A. Gottlieb, Helen B. Burks, Anja Karlstaedt, Rebecca Salazar, Jennifer VanEyk, David J. Taylor, An Dinh, Benjamin D. Gould, Daniel Soetkamp, Walter Schiffer, Blake Hanson, Heinrich Taegtmeyer, Weston R. Spivia, Daniel McNavish, Koen Raedschelders, Heidi Vitrac

Publikováno v: Circulation Research. 125

Metabolic rewiring is a hallmark of cancer and muscle cells. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate (D2-HG) are associated with systemic effects, including myopathy. Our r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::48e590eb88f724176a5a658c1fe101f6
https://doi.org/10.1161/res.125.suppl_1.361

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Abstract 452: Alpha-Ketoglutarate Dehydrogenase Inhibition by the Oncometabolite D2-HG Causes Proteome and Metabolome Remodeling in Myocytes

Autor: Weston R. Spivia, Koen Raedschelders, Anja Karlstaedt, Jennifer VanEyk, Heinrich Taegtmeyer, Daniel M, Radhika Khanna, Heidi Vitrac

Publikováno v: Circulation Research. 123

Autophagy “scavenges” proteins and yields amino acids under conditions of metabolic stress to support cell survival and growth. In isocitrate dehydrogenase 1 and 2 mutant tumors, increased plasma levels of the oncometabolite D-2-hydroxyglutarate

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::ee45a6b884a7d4a16361c4e083f4c677
https://doi.org/10.1161/res.123.suppl_1.452

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