Zobrazeno 1 - 1
of 1
pro vyhledávání: '"Jennifer Valiando"'
Autor:
Jennifer Valiando, Keiichi Kondo, Mircea Ivan, Adrian Salic, Haifeng Yang, John M. Asara, William G. Kaelin, Michael Ohh, William Y. Kim, William S. Lane
Publikováno v:
Science. 292:464-468
HIF (hypoxia-inducible factor) is a transcription factor that plays a pivotal role in cellular adaptation to changes in oxygen availability. In the presence of oxygen, HIF is targeted for destruction by an E3 ubiquitin ligase containing the von Hippe