Zobrazeno 1 - 10
of 52
pro vyhledávání: '"Jennifer V. Hines"'
Autor:
Md Ismail Hossain, Mason Myers, Danushika Herath, Ali H. Aldhumani, Hannah Boesger, Jennifer V. Hines
Publikováno v:
Biochemical and Biophysical Research Communications. 644:55-61
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2faf0f8fa1e212919ac05e565e1369
https://doi.org/10.1016/j.bbrc.2022.12.080
https://doi.org/10.1016/j.bbrc.2022.12.080
Autor:
Liyi Wang, Dennis A. Roberts, Yanrong Qian, Subhodip Adhicary, Xiaozhuo Chen, Pratik Shriwas, Stephen C. Bergmeier, Corinne M Nielsen, Yunsheng Li, Jennifer V. Hines
Publikováno v:
Cancer & Metabolism, Vol 9, Iss 1, Pp 1-14 (2021)
Cancer & Metabolism
Cancer & Metabolism
BackgroundCancer cells drastically increase the uptake of glucose and glucose metabolism by overexpressing class I glucose transporters (GLUT1-4) to meet their energy and biomass synthesis needs and are very sensitive and vulnerable to glucose depriv
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bbb52d243fb144466834ba3c43fc8fdc
https://doaj.org/article/611e928e026e4aef9d5a131d9ca0b291
https://doaj.org/article/611e928e026e4aef9d5a131d9ca0b291
Autor:
Fang Fang, Ali H. Aldhumani, Ian S. Armstrong, Jia L. Schopis, Jennifer V. Hines, Eric Parsons, Md. Ismail Hossain, Chunxi Zeng, Stephen C. Bergmeier
Publikováno v:
Bioorg Med Chem
Antibacterial drug resistance is a global health concern that requires multiple solution approaches including development of new antibacterial compounds acting at novel targets. Targeting regulatory RNA is an emerging area of drug discovery. The T-bo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e255a183d30c832348161ea818b66e1a
https://pubmed.ncbi.nlm.nih.gov/33069065
https://pubmed.ncbi.nlm.nih.gov/33069065
Autor:
Andrew B. Kouse, Hebaallaha Hussein, Franz Narberhaus, Jennifer V. Hines, Erin R. Murphy, Jacob P Sieg, Chunxi Zeng, Peter W. Coschigano, Johanna Roßmanith, Megan E. Fris, Kevin Gross
Publikováno v:
Infect Immun
RNA thermometers are cis-acting riboregulators that mediate the posttranscriptional regulation of gene expression in response to environmental temperature. Such regulation is conferred by temperature-responsive structural changes within the RNA therm
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f8442a4d910245099390656e30d5cecf
https://pubmed.ncbi.nlm.nih.gov/31792074
https://pubmed.ncbi.nlm.nih.gov/31792074
Autor:
Davoud Ghazanfari, Kelly D. McCall, Douglas J. Goetz, Jennifer V. Hines, Mahboubeh S. Noori, Stephen C. Bergmeier
Publikováno v:
Bioorg Med Chem
Glycogen synthase kinase-3 (GSK-3) has been implicated in numerous pathologies making GSK-3 an attractive therapeutic target. Our group has identified a compound termed COB-187 that is a potent and selective inhibitor of GSK-3. In this study, we prob
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6a1b341afd8e5d556dbe11566c7c2ffd
https://doi.org/10.1016/j.bmc.2021.116179
https://doi.org/10.1016/j.bmc.2021.116179
Autor:
Jennifer V. Hines
Publikováno v:
Science. 366:1322-1322
This year marks the 150th anniversary of Mendeleev9s publication on the periodic table. Periodic: A Game of the Elements provides a fun way to celebrate the science behind it in an engaging, play-based format.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::ed453ca2a6ff615757c30cd546e73e63
https://doi.org/10.1126/science.aba2746
https://doi.org/10.1126/science.aba2746
Autor:
Juan Ding, Huzoor Akbar, Yanyan Cao, Shiyong Wu, Lingying Tong, Weihe Zhang, Yanrong Qian, Xiaozhuo Chen, Stephen C. Bergmeier, Robert B. Colvin, Jennifer V. Hines, Liu Yi
Publikováno v:
Molecular Cancer Therapeutics. 11:1672-1682
The functional and therapeutic importance of the Warburg effect is increasingly recognized, and glycolysis has become a target of anticancer strategies. We recently reported the identification of a group of novel small compounds that inhibit basal gl
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ee7e73aa12a75febb4ae81314a3f2352
https://doi.org/10.1158/1535-7163.mct-12-0131
https://doi.org/10.1158/1535-7163.mct-12-0131
Autor:
Jennifer V. Hines, Iwona Maciagiewicz, Stephen C. Bergmeier, Shu Zhou, Dennis A. Roberts, Fang Fang
Publikováno v:
Synthesis. 2012:551-560
In continuation of an antibacterial discovery project, the ring-opening/rearrangement reaction of bicyclic oxaziridines with primary amines and KOtBu is studied.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c99c5bc112a98b4886e46bcafb9a1f58
https://doi.org/10.1055/s-0031-1289684
https://doi.org/10.1055/s-0031-1289684
Publikováno v:
Chemical Biology & Drug Design. 79:202-208
The T box antiterminator RNA element is an important component of the T box riboswitch that controls the transcription of vital genes in many Gram-positive bacteria. A series of 1,4-disubstituted 1,2,3-triazoles was screened in a fluorescence-monitor
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::9c2c94df7681457c9f94213f8ba01899
https://doi.org/10.1111/j.1747-0285.2011.01274.x
https://doi.org/10.1111/j.1747-0285.2011.01274.x