Zobrazeno 1 - 10
of 15
pro vyhledávání: '"Jennifer Tullman"'
Autor:
Brian D. Reed, Michael J. Meyer, Valentin Abramzon, Omer Ad, Pat Adcock, Faisal R. Ahmad, Gün Alppay, James A. Ball, James Beach, Dominique Belhachemi, Anthony Bellofiore, Michael Bellos, Juan Felipe Beltrán, Andrew Betts, Mohammad Wadud Bhuiya, Kristin Blacklock, Robert Boer, David Boisvert, Norman D. Brault, Aaron Buxbaum, Steve Caprio, Changhoon Choi, Thomas D. Christian, Robert Clancy, Joseph Clark, Thomas Connolly, Kathren Fink Croce, Richard Cullen, Mel Davey, Jack Davidson, Mohamed M. Elshenawy, Michael Ferrigno, Daniel Frier, Saketh Gudipati, Stephanie Hamill, Zhaoyu He, Sharath Hosali, Haidong Huang, Le Huang, Ali Kabiri, Gennadiy Kriger, Brittany Lathrop, An Li, Peter Lim, Stephen Liu, Feixiang Luo, Caixia Lv, Xiaoxiao Ma, Evan McCormack, Michele Millham, Roger Nani, Manjula Pandey, John Parillo, Gayatri Patel, Douglas H. Pike, Kyle Preston, Adeline Pichard-Kostuch, Kyle Rearick, Todd Rearick, Marco Ribezzi-Crivellari, Gerard Schmid, Jonathan Schultz, Xinghua Shi, Badri Singh, Nikita Srivastava, Shannon F. Stewman, TR Thurston, T. R. Thurston, Philip Trioli, Jennifer Tullman, Xin Wang, Yen-Chih Wang, Eric A. G. Webster, Zhizhuo Zhang, Jorge Zuniga, Smita S. Patel, Andrew D. Griffiths, Antoine M. van Oijen, Michael McKenna, Matthew D. Dyer, Jonathan M. Rothberg
Publikováno v:
Science. 378:186-192
Studies of the proteome would benefit greatly from methods to directly sequence and digitally quantify proteins and detect posttranslational modifications with single-molecule sensitivity. Here, we demonstrate single-molecule protein sequencing using
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::6d3367086ac787e208c4c79a68cbb83f
https://doi.org/10.1126/science.abo7651
https://doi.org/10.1126/science.abo7651
Publikováno v:
Applied Microbiology and Biotechnology. 104:7261-7271
Next-generation approaches for protein sequencing are now emerging that could have the potential to revolutionize the field in proteomics. One such sequencing method involves fluorescence-based imaging of immobilized peptides in which the N-terminal
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7508902ff8ac7eaef782f92b81ac76b1
https://doi.org/10.1007/s00253-020-10745-2
https://doi.org/10.1007/s00253-020-10745-2
Autor:
Brian D. Reed, Michael J. Meyer, Valentin Abramzon, Omer Ad, Pat Adcock, Faisal R. Ahmad, Gün Alppay, James A. Ball, James Beach, Dominique Belhachemi, Anthony Bellofiore, Michael Bellos, Juan Felipe Beltrán, Andrew Betts, Mohammad Wadud Bhuiya, Kristin Blacklock, Robert Boer, David Boisvert, Norman D. Brault, Aaron Buxbaum, Steve Caprio, Changhoon Choi, Thomas D. Christian, Robert Clancy, Joseph Clark, Thomas Connolly, Kathren Fink Croce, Richard Cullen, Mel Davey, Jack Davidson, Mohamed M. Elshenawy, Michael Ferrigno, Daniel Frier, Saketh Gudipati, Stephanie Hamill, Zhaoyu He, Sharath Hosali, Haidong Huang, Le Huang, Ali Kabiri, Gennadiy Kriger, Brittany Lathrop, An Li, Peter Lim, Stephen Liu, Feixiang Luo, Caixia Lv, Xiaoxiao Ma, Evan McCormack, Michele Millham, Roger Nani, Manjula Pandey, John Parillo, Gayatri Patel, Douglas H. Pike, Kyle Preston, Adeline Pichard-Kostuch, Kyle Rearick, Todd Rearick, Marco Ribezzi-Crivellari, Gerard Schmid, Jonathan Schultz, Xinghua Shi, Badri Singh, Nikita Srivastava, Shannon F. Stewman, T.R. Thurston, Philip Trioli, Jennifer Tullman, Xin Wang, Yen-Chih Wang, Eric A. G. Webster, Zhizhuo Zhang, Jorge Zuniga, Smita S. Patel, Andrew D. Griffiths, Antoine M. van Oijen, Michael McKenna, Matthew D. Dyer, Jonathan M. Rothberg
SummaryProteins are the main structural and functional components of cells, and their dynamic regulation and post-translational modifications (PTMs) underlie cellular phenotypes. Next-generation DNA sequencing technologies have revolutionized our und
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::456ffcbe72406d3c3c62ecb97937de66
https://doi.org/10.1101/2022.01.04.475002
https://doi.org/10.1101/2022.01.04.475002
Publikováno v:
Applied Microbiology and Biotechnology. 103:2621-2633
One of the central challenges in the development of single-molecule protein sequencing technologies is achieving high-fidelity sequential recognition and detection of specific amino acids that comprise the peptide sequence. An approach towards achiev
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::830f8eb6106628c746a7325fabce6178
https://doi.org/10.1007/s00253-019-09624-2
https://doi.org/10.1007/s00253-019-09624-2
Autor:
Kunal Dharmadhikari, Christina Bergonzo, Makenzie Christensen, Jennifer Tullman, Emily Samuels
Publikováno v:
ProteinsREFERENCES. 88(9)
ClpS2 is a small protein under development as a probe for selectively recognizing N-terminal amino acids of N-degron peptide fragments. To understand the structural basis of ClpS2 specificity for an N-terminal amino acid, all atom molecular dynamics
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ae4b52d345449eaf22d407f6f921084a
https://pubmed.ncbi.nlm.nih.gov/32181926
https://pubmed.ncbi.nlm.nih.gov/32181926
Publikováno v:
Engineering Reports, Vol 1, Iss 2, Pp n/a-n/a (2019)
Integral membrane proteins (IMPs) pose a challenge to study in vitro, as it is difficult to reproduce the membrane‐imbedded context of their native state. In this study, we developed a generalized strategy for the assembly of chimeric IMPs within a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5d906b215f00901a487fda22e3df575f
https://doi.org/10.1002/eng2.12040
https://doi.org/10.1002/eng2.12040
Publikováno v:
Trends Biochem Sci
Proteomic analysis can be a critical bottleneck in cellular characterization. The current paradigm relies primarily on mass spectrometry of peptides and affinity reagents (i.e., antibodies), both of which require a priori knowledge of the sample. An
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f7d826010f14a60ab91355d2cadb96bc
https://pubmed.ncbi.nlm.nih.gov/31676211
https://pubmed.ncbi.nlm.nih.gov/31676211
Publikováno v:
Biochemical Engineering Journal. 154:107438
Realization of binding reagents that can perform high-fidelity, sequential recognition and detection of amino acids is important for the success of many proposed approaches for single-molecule protein sequencing. Towards this purpose, a variant of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::39b2ad292e53aa5edd0c8a19cc288bac
https://doi.org/10.1016/j.bej.2019.107438
https://doi.org/10.1016/j.bej.2019.107438
Publikováno v:
Biotechnology and Bioengineering. 113:852-858
Protein switches have a variety of potential applications in biotechnology and medicine that motivate efforts to accelerate their development. Switches can be built by the proper fusion of two proteins with the prerequisite input and output functions
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::939d83707b4dcdf3bb4551b001861500
https://doi.org/10.1002/bit.25852
https://doi.org/10.1002/bit.25852
Publikováno v:
Plasmonics. 2:119-127
The interaction between peptides and gold surfaces has increasingly been of interest for bionanotechnology applications. To more fully understand how to control such interactions, we have studied the optical properties of peptide-modified gold nanopa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3274e19a183a0411841529f76d37f15
https://doi.org/10.1007/s11468-007-9033-z
https://doi.org/10.1007/s11468-007-9033-z