Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jennifer T. Wolstenholme"'
Autor:
Emily R. Brocato, Rachel Easter, Alanna Morgan, Meenakshi Kakani, Grace Lee, Jennifer T. Wolstenholme
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 17 (2024)
IntroductionBinge drinking in adolescence can disrupt myelination and cause brain structural changes that persist into adulthood. Alcohol consumption at a younger age increases the susceptibility of these changes. Animal models to understand ethanol
Externí odkaz:
https://doaj.org/article/db5111f3f206466aa88e2d6d1a88d00c
Autor:
Jennifer T. Wolstenholme, Justin M. Saunders, Maren Smith, Jason D. Kang, Phillip B. Hylemon, Javier González-Maeso, Andrew Fagan, Derrick Zhao, Masoumeh Sikaroodi, Jeremy Herzog, Amirhossein Shamsaddini, Marcela Peña-Rodríguez, Lianyong Su, Yun-Ling Tai, Jing Zheng, Po-Cheng Cheng, R. Balfour Sartor, Patrick M. Gillevet, Huiping Zhou, Jasmohan S. Bajaj
Publikováno v:
Nature Communications, Vol 13, Iss 1, Pp 1-14 (2022)
Gut microbiota composition is altered in patients with alcohol use disorder, and fecal microbiota transplant reduced alcohol craving in patients with alcohol use disorder and liver cirrhosis in a phase 1 clinical trial. Here the authors used stool sa
Externí odkaz:
https://doaj.org/article/71cd530afe02445e92a5c780310d4264
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 16 (2023)
Adolescence is marked in part by the ongoing development of the prefrontal cortex (PFC). Binge ethanol use during this critical stage in neurodevelopment induces significant structural changes to the PFC, as well as cognitive and behavioral deficits
Externí odkaz:
https://doaj.org/article/50ca9ee1006a43a8a3d0d59eb3e0b84b
Publikováno v:
Frontiers in Behavioral Neuroscience, Vol 16 (2022)
Adolescence is a critical developmental period characterized by enhanced social interactions, ongoing development of the frontal cortex and maturation of synaptic connections throughout the brain. Adolescents spend more time interacting with peers th
Externí odkaz:
https://doaj.org/article/8b1cabf3e5514e83a7c478f4b703f324
Autor:
Mario de la Fuente Revenga, Bohan Zhu, Christopher A. Guevara, Lynette B. Naler, Justin M. Saunders, Zirui Zhou, Rudy Toneatti, Salvador Sierra, Jennifer T. Wolstenholme, Patrick M. Beardsley, George W. Huntley, Chang Lu, Javier González-Maeso
Publikováno v:
Cell Reports, Vol 37, Iss 3, Pp 109836- (2021)
Summary: Clinical evidence suggests that rapid and sustained antidepressant action can be attained with a single exposure to psychedelics. However, the biological substrates and key mediators of psychedelics’ enduring action remain unknown. Here, w
Externí odkaz:
https://doaj.org/article/43705a14b3dc480c8aba3ee0cb75a2bd
Autor:
Anne D. Henriksen, Alejandro Andrade, Erin P. Harris, Emilie F. Rissman, Jennifer T. Wolstenholme
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 9, p 3129 (2020)
Bisphenol A (BPA) is an endocrine-disrupting compound detected in the urine of more than 92% of humans, easily crosses the placental barrier, and has been shown to influence gene expression during fetal brain development. The purpose of this study wa
Externí odkaz:
https://doaj.org/article/53b3ca5a227542f8b613764a7491f5dd
Autor:
Megan A. O’Brien, Rory M. Weston, Nihar U. Sheth, Steven Bradley, John Bigbee, Ashutosh Pandey, Robert W. Williams, Jennifer T. Wolstenholme, Michael F. Miles
Publikováno v:
Frontiers in Genetics, Vol 9 (2018)
Alcoholism is a complex behavioral disorder characterized by loss of control in limiting intake, and progressive compulsion to seek and consume ethanol. Prior studies have suggested that the characteristic behaviors associated with escalation of drug
Externí odkaz:
https://doaj.org/article/9b0ee6e80a1e4e28b6d511a72bf85f56
Autor:
Alexander B. Pais, Anthony C. Pais, Gabriel Elmisurati, So Hyun Park, Michael F. Miles, Jennifer T. Wolstenholme
Publikováno v:
Brain Sciences, Vol 9, Iss 12, p 336 (2019)
Adolescence is characterized by high levels of playful social interaction, cognitive development, and increased risk-taking behavior. Juvenile exposure to social isolation or social stress can reduce myelin content in the frontal cortex, alter neuron
Externí odkaz:
https://doaj.org/article/ac838c11ca774f39a9b62baa03df4f9a
Publikováno v:
Frontiers in Molecular Neuroscience, Vol 10 (2017)
Adolescents primarily consume alcohol in binges, which can be particularly harmful to the developing frontal cortex and increase risk for an adult alcohol use disorder. We conducted a study investigating immediate and long lasting changes to the pref
Externí odkaz:
https://doaj.org/article/462e53b1276946c096e337def2e1c225
Autor:
Javier González-Maeso, Jennifer T. Wolstenholme, Hiba Z. Vohra, Alaina M Jaster, Mario de la Fuente Revenga, Patrick M. Beardsley, Alberto Fernández-Teruel, Justin M. Saunders, Jennifer Jimenez
Publikováno v:
Psychopharmacology (Berl)
BACKGROUND: Prepulse inhibition (PPI) of startle is a sensorimotor gating phenomenon perturbed in a variety of neuropsychiatric conditions. Psychedelics disrupt PPI in rats and humans, but their effects and involvement of the serotonin 5-HT(2A) recep
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e159d4ba4cab0e46599646bd7e17de99
https://europepmc.org/articles/PMC10103008/
https://europepmc.org/articles/PMC10103008/