Zobrazeno 1 - 9
of 9
pro vyhledávání: '"Jennifer Sisler"'
Autor:
Ali Raza, Vidisha Raje, Jennifer Sisler, Marc Cantwell, Claudia Mertens, Heinz Baumann, Peter E. Shaw, Erin Tracy, Dipankar Bandyopadhyay, Andrew C. Larner, Jeremy Meier, Suzana Gispert, Moonjung Hyun, Kazuaki Takabe, Sylvia Torres-Odio
Publikováno v:
Science signaling. 10(472)
Signal transducer and activator of transcription 3 (STAT3) is associated with various physiological and pathological functions, mainly as a transcription factor that translocates to the nucleus upon tyrosine phosphorylation induced by cytokine stimul
Autor:
Andrew C. Larner, Qifang Zhang, Adly Yacoub, Vidisha Raje, Hossein A. Hamed, Paul Dent, Vasily A. Yakovlev, Marta Derecka, Qun Chen, Kristoffer Valerie, Ying Hu, Jeremy Meier, Edward J. Lesnefsky, Jennifer Sisler, Karol Szczepanek
Publikováno v:
Journal of Biological Chemistry. 288:31280-31288
Signal transducer and activator of transcription 3 (Stat3) is a key mediator in the development of many cancers. For 20 years, it has been assumed that Stat3 mediates its biological activities as a nuclear localized transcription factor activated by
Autor:
Marc Cantwell, Birgit Strobl, Marta Derecka, Karol Szczepanek, Jennifer Sisler, Thurl E. Harris, Vidisha Raje, Jeremy Meier, Ana M. Gamero, Andrew C. Larner
Publikováno v:
Endocrinology. :en.2015-2048
It has been known for decades that brown adipose tissue (BAT) plays a central role in maintaining body temperature in hibernating animals and human infants. Recently, it has become evident that there are also depots of brown fat in adult humans, and
Autor:
Jennifer Sisler, Marta Derecka, Andrew C. Larner, Susanna R. Keller, Karol Szczepanek, Vidisha Raje, Magdalena Morgan, Agnieszka Gornicka
Publikováno v:
The FASEB Journal. 26
Autor:
Vidisha B Raje, Marta Derecka, Agnieszka Gornicka, Karol Sczepanek, Jennifer Sisler, Colleen M Croniger, Andrew Larner
Publikováno v:
The FASEB Journal. 26
Obesity develops when energy intake exceeds energy expenditure. Defect in the function of brown fat and skeletal muscle, two of the major tissues that contribute towards energy expenditure, lead to the development of obesity and metabolic syndrome. O
Autor:
Rebecca C. Grande, Karol Szczepanek, Marta Derecka, Thurl E. Harris, Vidisha Raje, Andrew C. Larner, Marc Cantwell, Magdalena Morgan, Colleen M. Croniger, Jeremy Meier, Edward J. Lesnefsky, William J. Korzun, Jennifer Sisler
Publikováno v:
PLoS ONE, Vol 10, Iss 12, p e0144444 (2015)
PLoS ONE
PLoS ONE
The transcription factor STAT1 plays a central role in orchestrating responses to various pathogens by activating the transcription of nuclear-encoded genes that mediate the antiviral, the antigrowth, and immune surveillance effects of interferons an
Autor:
Ramesh Potla, Jennifer Sisler, Paul Dent, Magdalena Szelag, Andrew C. Larner, Hossein A. Hamed
Publikováno v:
Cytokine. 48:123-124
Autor:
Vidisha Raje, Karol Szczepanek, Marta Derecka, Edward J. Lesnefsky, Jennifer Sisler, Andrew C. Larner, Magdalena Szelag
Publikováno v:
Cytokine. 63:301
Stat1 plays a central role in orchestrating responses to a variety of pathogens by activating the transcription of nuclear encoded genes that mediate the antiviral, antigrowth, and the immune surveillance effects of interferons. Previous studies have
Autor:
Aaron P. Russell, Dennis C. Otero, Tomasz Kordula, Susanna R. Keller, Birgit Strobl, Agnieszka Gornicka, Magdalena Morgan, Sandra Pellegrini, Patrick Seale, Karol Szczepanek, Andrew J. McAinch, Kazuya Shimoda, Klaus Rajewsky, Marta Derecka, Colleen M. Croniger, Qifang Zhang, Sergei B. Koralov, Valeria Poli, Thurl E. Harris, Vidisha Raje, Paul E. O'Brien, Andrew C. Larner, Joanna Cichy, Jennifer Sisler
Publikováno v:
Cell Metabolism. (6):814-824
SummaryMice lacking the Jak tyrosine kinase member Tyk2 become progressively obese due to aberrant development of Myf5+ brown adipose tissue (BAT). Tyk2 RNA levels in BAT and skeletal muscle, which shares a common progenitor with BAT, are dramaticall