Zobrazeno 1 - 8
of 8
pro vyhledávání: '"Jennifer Schröder-Schwarz"'
Autor:
Arun Everest‐Dass, Stepan Nersisyan, Hanna Maar, Victor Novosad, Jennifer Schröder‐Schwarz, Vera Freytag, Johanna L. Stuke, Mia C. Beine, Alina Schiecke, Marie‐Therese Haider, Malte Kriegs, Omar Elakad, Hanibal Bohnenberger, Lena‐Christin Conradi, Maria Raygorodskaya, Linda Krause, Mark vonItzstein, Alexander Tonevitsky, Udo Schumacher, Diana Maltseva, Daniel Wicklein, Tobias Lange
Publikováno v:
Molecular Oncology, Vol 18, Iss 1, Pp 62-90 (2024)
Hematogenous metastasis limits the survival of colorectal cancer (CRC) patients. Here, we illuminated the roles of CD44 isoforms in this process. Isoforms 3 and 4 were predominantly expressed in CRC patients. CD44 isoform 4 indicated poor outcome and
Externí odkaz:
https://doaj.org/article/c19589a2bdca416b84704f2b8e082ac3
Autor:
Tanja Spethmann, Lukas Clemens Böckelmann, Vera Labitzky, Ann‐Kristin Ahlers, Jennifer Schröder‐Schwarz, Sarah Bonk, Ronald Simon, Guido Sauter, Hartwig Huland, Robert Kypta, Udo Schumacher, Tobias Lange
Publikováno v:
Molecular Oncology, Vol 15, Iss 7, Pp 1956-1969 (2021)
Both oncogenic and tumor suppressor functions have been described for junction plakoglobin (JUP), also known as γ‐catenin. To clarify the role of JUP in prostate cancer, JUP protein expression was immunohistochemically detected in a tissue microar
Externí odkaz:
https://doaj.org/article/7121450caf7b4f2591affd5fcf9ae787
Autor:
Daniel Wicklein, Benjamin Otto, Anna Suling, Eva Elies, Georg Lüers, Tobias Lange, Susanne Feldhaus, Hanna Maar, Jennifer Schröder-Schwarz, Georg Brunner, Christoph Wagener, Udo Schumacher
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Abstract We investigated the functional role of CEACAM1 in a spontaneous metastasis xenograft model of human melanoma in scid mice using BRAF wildtype MeWo cells with and without RNAi mediated knockdown of CEACAM1. Tumors from the xenograft model wer
Externí odkaz:
https://doaj.org/article/18afeaf98aab49c89e5e0549bf4f9baf
Autor:
Ann-Kathrin Ernst, Annika Putscher, Timur R Samatov, Anna Suling, Vladimir V Galatenko, Maxim Yu Shkurnikov, Evgeny N Knyazev, Alexander G Tonevitsky, Thomas Haalck, Tobias Lange, Hanna Maar, Jennifer Schröder-Schwarz, Kristoffer Riecken, Udo Schumacher, Daniel Wicklein
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192525 (2018)
Finding additional functional targets for combination therapy could improve the outcome for melanoma patients. In a spontaneous metastasis xenograft model of human melanoma a shRNA mediated knockdown of L1CAM more than sevenfold reduced the number of
Externí odkaz:
https://doaj.org/article/35f4bb6c08f24b1ea2f9c87854f2c513
Autor:
Jennifer Schröder-Schwarz, Mascha Binder, Savithri Rangarajan, Christian Müller, Udo Schumacher, Nikolaus Möckelmann, Chia-Jung Busch, Tobias Lange, Konstantin Hoffer, Lara Marie Akingunsade, Conrad Droste, Henrike Barbara Zech, Lukas Clemens Böckelmann, Julia Kemmling, Anh Thu Vu, Lara Bußmann, Fruzsina Gatzemeier, Till S. Clauditz, Nina Struve, Malte Kriegs, Konrad Klinghammer, Donjete Simnica, Christian Stephan Betz, Peter Nollau, Cordula Petersen, Agnes Oetting, Thorsten Rieckmann, Adrian Münscher, Rik de Wijn, Arne Böttcher, Joanna Caroline Berger, Clara Marie von Bargen, Kai Rothkamm
Publikováno v:
International journal of cancerREFERENCES. 149(5)
Signal transduction via protein kinases is of central importance in cancer biology and treatment. However, the clinical success of kinase inhibitors is often hampered by a lack of robust predictive biomarkers, which is also caused by the discrepancy
Autor:
Tobias Lange, Daniel Wicklein, Hanna Maar, Georg Brunner, Christoph Wagener, Susanne Feldhaus, Jennifer Schröder-Schwarz, Udo Schumacher, Anna Suling, Benjamin Otto, Eva Elies, Georg H. Lüers
Publikováno v:
Scientific Reports
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
Scientific Reports, Vol 8, Iss 1, Pp 1-13 (2018)
We investigated the functional role of CEACAM1 in a spontaneous metastasis xenograft model of human melanoma in scid mice using BRAF wildtype MeWo cells with and without RNAi mediated knockdown of CEACAM1. Tumors from the xenograft model were subject
Autor:
Vladimir V. Galatenko, Alexander G. Tonevitsky, Kristoffer Riecken, E N Knyazev, Maxim Shkurnikov, Hanna Maar, Annika Putscher, Ann-Kathrin Ernst, Anna Suling, Thomas Haalck, Tobias Lange, Timur R. Samatov, Udo Schumacher, Daniel Wicklein, Jennifer Schröder-Schwarz
Publikováno v:
PLoS ONE, Vol 13, Iss 2, p e0192525 (2018)
PLoS ONE
PLoS ONE
Finding additional functional targets for combination therapy could improve the outcome for melanoma patients. In a spontaneous metastasis xenograft model of human melanoma a shRNA mediated knockdown of L1CAM more than sevenfold reduced the number of
Autor:
Jennifer Schröder-Schwarz, Katrin Stübke, Tobias Lange, Hartwig Huland, Olaf J C Hellwinkel, Guido Sauter, Sebastian Ullrich, Udo Schumacher, Thorsten Schlomm, Christine Knies, Michael F. Nentwich, Robert L. Vessella, Claudia Abramjuk, Mario Anders, Imke Müller, Susanne Feldhaus
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 18(5)
Purpose: To establish xenograft mouse models of metastatic and nonmetastatic human prostate cancer and to apply these models to the search for aberrant glycosylation patterns associated with tumor progression in vivo and in patients. Experimental Des