Zobrazeno 1 - 10
of 13
pro vyhledávání: '"Jennifer Schürenkamp"'
Publikováno v:
International Journal of Legal Medicine
(−)-Δ-9-tetrahydrocannabinol ((−)-Δ-9-THC) is the main psychoactive constituent in cannabis. During phase I metabolism, it is metabolized to (−)-11-hydroxy-Δ-9-tetrahydrocannabinol ((−)-11-OH-Δ-9-THC), which is psychoactive, and to (−)-
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::5fe6668b983323f86a9e01698f04b2ac
https://doi.org/10.1007/s00414-020-02387-w
https://doi.org/10.1007/s00414-020-02387-w
Publikováno v:
International Journal of Legal Medicine
While the impact of genetic polymorphisms on the metabolism of various pharmaceuticals is well known, more data are needed to better understand the specific influence of pharmacogenetics on the metabolism of delta 9-tetrahydocannabinol (Δ9-THC). The
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c2fad3aa55e0eff240674714a4919dab
https://doi.org/10.1007/s00414-020-02380-3
https://doi.org/10.1007/s00414-020-02380-3
Autor:
M. Schürenkamp, Angela Gasse, Heidi Pfeiffer, Jennifer Schürenkamp, Julia Sophie Schneider, Ursula Sibbing, Marielle Vennemann, Sabrina Banken
Publikováno v:
International Journal of Legal Medicine. 133:365-372
We present a novel multiplex assay for the simultaneous detection of 12 polymorphisms within the UGT1A9 sequence, which codes for enzymes involved in phase II biotransformation. The assay combines a multiplexed amplification step with single-base ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::36c2f41dca7d1e67c10a08c3d2e90021
https://doi.org/10.1007/s00414-018-1919-0
https://doi.org/10.1007/s00414-018-1919-0
Autor:
Franziska Gaunitz, Ayda Rostamzadeh, Markus A. Rothschild, Mario Thevis, Katja Mercer-Chalmers-Bender, Christian Konkol, Jennifer Schürenkamp
Publikováno v:
Forensic Toxicology. 35:421-427
This case report deals with a 25-year-old woman who suffered from a long-term borderline personality disorder and from acute suicidal tendencies, including the intentional consumption of poisonous plants. When questioned during her self-referral to t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::40a8c6cd839baa97350ca4c651ba4b51
https://doi.org/10.1007/s11419-017-0355-z
https://doi.org/10.1007/s11419-017-0355-z
Publikováno v:
International Journal of Legal Medicine. 130:967-974
The aim of this work was to develop and validate a solid-phase extraction (SPE) method for the analysis of cannabinoids with emphasis on a very extensive and effective matrix reduction in order to ensure constant good results in selectivity and sensi
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::841b8d9e87083e83e9e0f46ab08df394
https://doi.org/10.1007/s00414-016-1368-6
https://doi.org/10.1007/s00414-016-1368-6
Autor:
Julia Sophie, Schneider, Angela, Gasse, Marianne, Schürenkamp, Ursula, Sibbing, Sabrina, Banken, Heidi, Pfeiffer, Jennifer, Schürenkamp, Marielle, Vennemann
Publikováno v:
International journal of legal medicine. 133(2)
We present a novel multiplex assay for the simultaneous detection of 12 polymorphisms within the UGT1A9 sequence, which codes for enzymes involved in phase II biotransformation. The assay combines a multiplexed amplification step with single-base ext
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::6ebfd12c5ea3f3e40dba7739beb26d3d
https://pubmed.ncbi.nlm.nih.gov/30191314
https://pubmed.ncbi.nlm.nih.gov/30191314
Publikováno v:
International journal of legal medicine. 132(1)
The ∆9-tetrahydrocannabinol (THC) metabolites 8β-hydroxy-THC and 8β,11-dihydroxy-THC are mentioned in the literature as potential blood markers of recent cannabis use. However, the formation of these metabolites in in vivo detectable concentratio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4822c17c5f1aba05b79ed234034234da
https://pubmed.ncbi.nlm.nih.gov/28983686
https://pubmed.ncbi.nlm.nih.gov/28983686
Publikováno v:
Journal of Analytical Toxicology. 39:126-129
A method for the simultaneous extraction of the hallucinogens psilocin, bufotenine, lysergic acid diethylamide (LSD) as well as iso-LSD, nor-LSD and O-H-LSD from hair with hydrochloride acid and methanol is presented. Clean-up of the hair extracts is
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::685e40eec6f795bac9cc40bdfd75e776
https://doi.org/10.1093/jat/bku141
https://doi.org/10.1093/jat/bku141
Publikováno v:
Forensic Science International. 237:1-6
A two-step synthesis of psilocin glucuronide (PCG), the main metabolite of psilocin, with methyl 2,3,4-tri-O-isobutyryl-1-O-trichloroacetimidoyl-α-d-glucopyranuronate is reported. With the synthesized PCG, hydrolysis conditions in serum and urine we
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::8d48a69493e12f56eecbcccc48f31a5b
https://doi.org/10.1016/j.forsciint.2014.01.006
https://doi.org/10.1016/j.forsciint.2014.01.006