Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jennifer S. Lucas"'
Autor:
Wen Cai, Mary Hassani, Nicholas G. Hermann, Anthony S. Rose, Jennifer S. Lucas, Thomas J. Eads, Ervin D. Walter, Minoo Sedighi, Sahba Charkhzarrin, Katherine H. Koelsch, Mohammad Behforouz, Hamid Mirzaei, Fatemeh Olang, Howard D. Beall, Hassan Seradj, Rajesh Karki, Jayana P. Lineswala, Jeremy S. York
Publikováno v:
Bioorganic & Medicinal Chemistry. 18:1899-1909
A series of lavendamycin analogues with two, three or four substituents at the C-6, C-7 N, C-2′, C-3′ and C-11′ positions were synthesized via short and efficient methods and evaluated as potential NAD(P)H:quinone oxidoreductase (NQO1)-directed
Autor:
Nancy C. Behforouz, Aiqin Wang, Wen Cai, Kevin S. Katen, Daniel Briere, Mark G. Stocksdale, Mohammad Behforouz, Joo Yong Jung, Jennifer S. Lucas
Publikováno v:
Journal of Medicinal Chemistry. 46:5773-5780
Novel lavendamycins including two water soluble derivatives were synthesized via short and efficient methods. Pictet-Spengler condensation of 7-N-acylamino-2-formylquinoline-5,8-diones with tryptophans produced lavendamycin esters or amides 11-17. La