Zobrazeno 1 - 10
of 55
pro vyhledávání: '"Jennifer S. Hovis"'
Publikováno v:
Journal of the American Chemical Society. 138:9996-10001
Lipid rafts are widely believed to be an essential organizational motif in cell membranes. However, direct evidence for interactions among lipid and/or protein components believed to be associated with rafts is quite limited owing, in part, to the sm
Publikováno v:
The Journal of Physical Chemistry B. 114:4070-4081
The interaction of alpha-synuclein with phospholipid membranes has been examined using supported lipid bilayers and epi-fluorescence microscopy. The membranes contained phosphatidylcholine (PC) and phosphatidic acid (PA), which mix at physiological p
Publikováno v:
Biophysical Journal. 96:540-551
Alpha-synuclein is the major component of Lewy body inclusions found in the brains of patients with Parkinson's disease. Several studies indicate that alpha-synuclein binds to negatively charged phospholipid bilayers. We examined the binding of alpha
Publikováno v:
Langmuir. 25:71-74
Cell membranes are continually undergoing a wide range of shape transformations. Here, we demonstrate the formation of several structures in supported bilayers, including tubules, caps, and giant multivesicular structures. The key elements required f
Autor:
Jennifer S. Hovis, Lee R. Cambrea
Publikováno v:
Biophysical Journal. 92:3587-3594
The creation of three-dimensional structures in supported lipid bilayers has been examined. In bilayers, shape transformations can be triggered by adjusting a variety of parameters. Here, it is shown that bilayers composed of phosphatidylcholine and
Autor:
Jennifer S. Hovis, Catherine C. Logisz
Publikováno v:
Biochimica et Biophysica Acta (BBA) - Biomembranes. 1717(2):104-108
Cell membranes are capable of withstanding significant osmotic stress, the exact amount of which varies with the lipid composition. In this paper, we examine the effect that salt concentration has on the lysis pressure of membranes containing anionic
Publikováno v:
Analytical Chemistry. 77:6096-6099
Infrared spectroscopy is a powerful technique for examining lipid bilayers; however, it says little about the fluidity of the bilayer-a key physical aspect. It is shown here that it is possible to both acquire spectroscopic data of supported lipid bi
Publikováno v:
The Journal of Physical Chemistry B. 108:15890-15895
The cell membrane can withstand significant osmotic stress before pores open to relieve the tension. The amount of stress that the membrane can withstand is determined by the lipid chemistry; we have examined the effect of four non-bilayer forming li
Autor:
Jennifer S. Hovis, James E. Butler, Mark P. D'Evelyn, John N. Russell, Robert J. Hamers, Stacey F. Bent, George T. Wang
Publikováno v:
Materials Chemistry and Physics. 72:147-151
The dimers on clean diamond (1 0 0)-2×1 are linked by a σ bond and a highly strained π bond. The weakness of the surface π bond causes the reactivity of this surface to be intermediate between that of an alkene and a bi-radical. We illustrate thi
Autor:
Jennifer S. Hovis and, Steven G. Boxer
Publikováno v:
Langmuir. 17:3400-3405
Fluid-supported lipid bilayers self-assemble on glass and SiO2 surfaces. We have found that it is also possible to assemble fluid bilayers on plasma-oxidized polydimethyl siloxane (PDMS) surfaces. Furthermore, it is possible to transfer or print the