Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer S Childs"'
Autor:
Mary L Disis, John B Liao, Doreen M Higgins, Jennifer S Childs, Sasha E Stanton, Anna V Tinker, William R Gwin, Renata R Urban, Katie M Hitchcock-Bernhardt, Andrew L Coveler, Hania N Shakalia, Ron E Swensen, Tanya A Wahl, Richard G Ancheta, Kathryn F McGonigle, James Y Dai, Barbara A Goff
Publikováno v:
Journal for ImmunoTherapy of Cancer, Vol 9, Iss 9 (2021)
Externí odkaz:
https://doaj.org/article/fa0344d0725b4c7788695fafcc3f18e8
Autor:
Mary L. Disis, Yushe Dang, Andrew L. Coveler, Jennifer S. Childs, Doreen M. Higgins, Ying Liu, Jing Zhou, Sean Mackay, Lupe G. Salazar
Publikováno v:
Clinical Cancer Research. :OF1-OF10
Purpose: High levels of type I T cells are needed for tumor eradication. We evaluated whether the HER2-specific vaccine–primed T cells are readily expanded ex vivo to achieve levels needed for therapeutic infusion. Patients and Methods: Phase I/II
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::e05a48e2d7762599bcb9201063e71427
https://doi.org/10.1158/1078-0432.ccr-22-3578
https://doi.org/10.1158/1078-0432.ccr-22-3578
Autor:
Lupe G. Salazar, Sean Mackay, Jing Zhou, Ying Liu, Doreen M. Higgins, Jennifer S. Childs, Andrew L. Coveler, Yushe Dang, Mary L. Disis
Flow chart of participants.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::303b86c44495461d46e57265526d3563
https://doi.org/10.1158/1078-0432.22802188.v1
https://doi.org/10.1158/1078-0432.22802188.v1
Autor:
Lupe G. Salazar, Sean Mackay, Jing Zhou, Ying Liu, Doreen M. Higgins, Jennifer S. Childs, Andrew L. Coveler, Yushe Dang, Mary L. Disis
Detailed adverse events.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::100382b238e59f5964e5586c055adc3d
https://doi.org/10.1158/1078-0432.22802179
https://doi.org/10.1158/1078-0432.22802179
Autor:
Lupe G. Salazar, Sean Mackay, Jing Zhou, Ying Liu, Doreen M. Higgins, Jennifer S. Childs, Andrew L. Coveler, Yushe Dang, Mary L. Disis
Purpose:High levels of type I T cells are needed for tumor eradication. We evaluated whether the HER2-specific vaccine–primed T cells are readily expanded ex vivo to achieve levels needed for therapeutic infusion.Patients and Methods:Phase I/II non
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7e012bc0e2d1134d2773e9c3db0e593e
https://doi.org/10.1158/1078-0432.c.6641713
https://doi.org/10.1158/1078-0432.c.6641713
Autor:
Mary L. Disis, Doreen M. Higgins, Jennifer S. Childs, Yi Yang, Angela Kask, Andrew L. Coveler, Yushe Dang, John B. Liao, Denise L. Cecil
Detailed Adverse Events and Flow diagram of patients progression through the trial .
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2131bf9d7e10592a5db6478cc0683b0c
https://doi.org/10.1158/1078-0432.22483589.v1
https://doi.org/10.1158/1078-0432.22483589.v1
Autor:
Mary L. Disis, Doreen M. Higgins, Jennifer S. Childs, Yi Yang, Angela Kask, Andrew L. Coveler, Yushe Dang, John B. Liao, Denise L. Cecil
Purpose:Cancer vaccines targeting nonmutated proteins elicit limited type I T-cell responses and can generate regulatory and type II T cells. Class II epitopes that selectively elicit type I or type II cytokines can be identified in nonmutated cancer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0affd293b049ceaae9de5a483ea6956a
https://doi.org/10.1158/1078-0432.c.6531173.v1
https://doi.org/10.1158/1078-0432.c.6531173.v1
Autor:
Sasha E. Stanton, Kari B. Wisinski, William R. Gwin, Andrew Coveler, John B. Liao, Mark Burkard, Howard Bailey, KyungMann Kim, Thomas Havinghurst, Katina DeShong, Jennifer S. Childs, Eileen Dimond, Margaret Wojtowicz, Brandy M. Heckman-Stoddard, Denise Cecil, Mary Disis
Publikováno v:
Cancer Research. 83:P2-02
Background: HER2, IGFBP-2, and IGF-IR are proteins that are overexpressed in breast cancer. These three proteins, when used as immunogens, provide broad antigenic coverage to all molecular breast cancer subtypes. The proteins are also up-regulated in
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d53f0853194076308345a7fb8383f362
https://doi.org/10.1158/1538-7445.sabcs22-p2-02-02
https://doi.org/10.1158/1538-7445.sabcs22-p2-02-02
Autor:
Mary L. (Nora) Disis, Katherine A. Guthrie, Ying Liu, Andrew L. Coveler, Doreen M. Higgins, Jennifer S. Childs, Yushe Dang, Lupe G. Salazar
Publikováno v:
JAMA Oncology. 9:71
ImportanceHigh levels of ERBB2 (formerly HER2)–specific type 1 T cells in the peripheral blood are associated with favorable clinical outcomes after trastuzumab therapy; however, only a minority of patients develop measurable ERBB2 immunity after t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::337e5551a6765204a8daa5d035e98043
https://doi.org/10.1001/jamaoncol.2022.5143
https://doi.org/10.1001/jamaoncol.2022.5143
Autor:
Lauren R. Corulli, Denise L. Cecil, Ekram Gad, Marlese Koehnlein, Andrew L. Coveler, Jennifer S. Childs, Ronald A. Lubet, Mary L. Disis
Publikováno v:
Frontiers in Immunology, Vol 12 (2021)
BackgroundOverexpression of nonmutated proteins involved in oncogenesis is a mechanism by which such proteins become immunogenic. We questioned whether overexpressed colorectal cancer associated proteins found at higher incidence and associated with
Externí odkaz:
https://doaj.org/article/3015375de6f44692a214a513d19c7329