Zobrazeno 1 - 10
of 168
pro vyhledávání: '"Jennifer S, Yu"'
Autor:
Rashmi Bharti, Goutam Dey, Debjit Khan, Alex Myers, Olivia G. Huffman, Caner Saygin, Chad Braley, Elliott Richards, Naseer Sangwan, Belinda Willard, Justin D. Lathia, Paul L. Fox, Feng Lin, Babal Kant Jha, J. Mark Brown, Jennifer S. Yu, Mohammed Dwidar, Amy Joehlin-Price, Roberto Vargas, Chad M. Michener, Michelle S. Longworth, Ofer Reizes
Publikováno v:
Molecular Cancer, Vol 23, Iss 1, Pp 1-23 (2024)
Abstract Background Platinum resistance is the primary cause of poor survival in ovarian cancer (OC) patients. Targeted therapies and biomarkers of chemoresistance are critical for the treatment of OC patients. Our previous studies identified cell su
Externí odkaz:
https://doaj.org/article/adfec356b7014a638df6edb322f5b4fb
Autor:
Rakhee Banerjee, Chase J. Wehrle, Zeneng Wang, Jennifer D. Wilcox, Vinayak Uppin, Venkateshwari Varadharajan, Marko Mrdjen, Courtney Hershberger, Ofer Reizes, Jennifer S. Yu, Justin D. Lathia, Daniel M. Rotroff, Stanley L. Hazen, W. H. Wilson Tang, Federico Aucejo, J. Mark Brown
Publikováno v:
Biomedicines, Vol 12, Iss 9, p 1946 (2024)
Hepatocellular carcinoma (HCC) is the third leading cause of cancer death worldwide. The gut microbiome has been implicated in outcomes for HCC, and gut microbe-derived products may serve as potential non-invasive indices for early HCC detection. Thi
Externí odkaz:
https://doaj.org/article/a62200dc1b60493abf45e69dac2752b1
Autor:
Jing Hao, Xiangzi Han, Haidong Huang, Xingjiang Yu, Jiankang Fang, Jianjun Zhao, Richard A. Prayson, Shideng Bao, Jennifer S. Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-12 (2023)
Abstract The Wnt pathway is frequently dysregulated in many cancers, underscoring it as a therapeutic target. Wnt inhibitors have uniformly failed in clinical trials. Here, we report a mechanism of WNT pathway activation through the Semaphorin 3 C ne
Externí odkaz:
https://doaj.org/article/755b7c691e6f4c8daf2bd64dcdd8c5bd
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
In the United States, an individual’s access to resources, insurance status, and wealth are critical social determinants that affect both the risk and outcomes of many diseases. One disease for which the correlation with socioeconomic status (SES)
Externí odkaz:
https://doaj.org/article/fc0ec7d1f10c47f8b2671face668118f
Autor:
Jing Hao, Xiangzi Han, Haidong Huang, Xingjiang Yu, Jiankang Fang, Jianjun Zhao, Richard A. Prayson, Shideng Bao, Jennifer S. Yu
Publikováno v:
Nature Communications, Vol 14, Iss 1, Pp 1-1 (2023)
Externí odkaz:
https://doaj.org/article/a2dd8912850549ceb2df62b7241c2302
Autor:
Cole Billena, Mina Lobbous, Christine A. Cordova, David Peereboom, Alejandro Torres-Trejo, Timothy Chan, Erin Murphy, Samuel T. Chao, John Suh, Jennifer S. Yu
Publikováno v:
Frontiers in Oncology, Vol 13 (2023)
Brain metastases are a significant source of morbidity and mortality in patients with non-small cell lung cancer. Historically, surgery and radiation therapy have been essential to maintaining disease control within the central nervous system due to
Externí odkaz:
https://doaj.org/article/58c29896976346619972a2b2dcdb3770
Autor:
Santiago Haase, Kaushik Banerjee, Anzar A. Mujeeb, Carson S. Hartlage, Fernando M. Núñez, Felipe J. Núñez, Mahmoud S. Alghamri, Padma Kadiyala, Stephen Carney, Marcus N. Barissi, Ayman W. Taher, Emily K. Brumley, Sarah Thompson, Justin T. Dreyer, Caitlin T. Alindogan, Maria B. Garcia-Fabiani, Andrea Comba, Sriram Venneti, Visweswaran Ravikumar, Carl Koschmann, Ángel M. Carcaboso, Maria Vinci, Arvind Rao, Jennifer S. Yu, Pedro R. Lowenstein, Maria G. Castro
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 22 (2022)
Pediatric high-grade gliomas (pHGGs) are the leading cause of cancer-related deaths in children in the USA. Sixteen percent of hemispheric pediatric and young adult HGGs encode Gly34Arg/Val substitutions in the histone H3.3 (H3.3-G34R/V). The mechani
Externí odkaz:
https://doaj.org/article/86291c23bf8d4ccda5764eae5949072f
Autor:
Weiwei Tao, Aili Zhang, Kui Zhai, Zhi Huang, Haidong Huang, Wenchao Zhou, Qian Huang, Xiaoguang Fang, Briana C Prager, Xiuxing Wang, Qiulian Wu, Andrew E Sloan, Manmeet S Ahluwalia, Justin D Lathia, Jennifer S Yu, Jeremy N Rich, Shideng Bao
Publikováno v:
EMBO Molecular Medicine, Vol 12, Iss 12, Pp 1-20 (2020)
Abstract Nuclear matrix‐associated proteins (NMPs) play critical roles in regulating chromatin organization and gene transcription by binding to the matrix attachment regions (MARs) of DNA. However, the functional significance of NMPs in glioblasto
Externí odkaz:
https://doaj.org/article/a5397199295d45629c5bcb2033be3620
Dual Role of WISP1 in maintaining glioma stem cells and tumor-supportive macrophages in glioblastoma
Autor:
Weiwei Tao, Chengwei Chu, Wenchao Zhou, Zhi Huang, Kui Zhai, Xiaoguang Fang, Qian Huang, Aili Zhang, Xiuxing Wang, Xingjiang Yu, Haidong Huang, Qiulian Wu, Andrew E. Sloan, Jennifer S. Yu, Xiaoxia Li, George R. Stark, Jeremy N. Rich, Shideng Bao
Publikováno v:
Nature Communications, Vol 11, Iss 1, Pp 1-16 (2020)
The tumour microenvironment plays an important role in promoting glioblastoma. Here, the authors show that glioma stem cells secrete WISP1, which promotes both the survival of the stem cells and tumour-associated macrophages.
Externí odkaz:
https://doaj.org/article/80ed06b6daa44b72a61177b8c8e47066
Autor:
Sharvari Dharmaiah, Johnathan Zeng, Vinay S. Rao, Zi Ouyang, Tianjun Ma, Kevin Yu, Heeruk Bhatt, Chirag Shah, Andrew Godley, Ping Xia, Jennifer S. Yu
Publikováno v:
International Journal of Hyperthermia, Vol 36, Iss 1, Pp 985-991 (2019)
Background: Treatment for locally recurrent breast cancer poses a significant challenge because the benefits in local control must be weighed against the increased risk of side effects of the treatment. Frequently, patients have been heavily pre-trea
Externí odkaz:
https://doaj.org/article/be8b697cd6b9445f8f7040d6618a742a