Zobrazeno 1 - 3
of 3
pro vyhledávání: '"Jennifer Ruprich"'
Autor:
R.R. Davis, Jennifer Ruprich, Christopher Tronrud, John A. Hartley, Konstantinos Kiakos, Toni Rice, Hilary Mackay, Sharjeel A Tahir, Laura M. Westrate, Balaji Babu, Jerome Kluza, Chrystal D. Bruce, Andrew T. Franks, Chandler Adkins, Sameer Chavda, W. David Wilson, Moses Lee, Alan Sielaff, Yang Liu, Shicai Lin, Amanda Ferguson, Samuel Tzou
Publikováno v:
Biochemistry. 50:3127-3136
With the aim of incorporating a recognition element that acts as a fluorescent probe upon binding to DNA, three novel pyrrole (P) and imidazole (I)-containing polyamides were synthesized. The compounds contain a p-anisylbenzimidazolecarboxamido (Hx)
Autor:
Khyati Baxi, Brent Younglove, Herman L. Holt, Lawrence Nolan, John Dickson, Lori Forrest, Moses Lee, Toni Brown, Jennifer Ruprich, Regan M. LeBlanc, Andrew Prout, Hilary Mackay, Susan L. Mooberry, Patrice Hills
Publikováno v:
Letters in Drug Design & Discovery. 4:144-148
Autor:
Amanda Ferguson, Hilary Mackay, Laura M. Westrate, Jennifer Ruprich, David Wilson, Toni Brown, Yang Liu, Daniel Hochhauser, Moses Lee, Konstantinos Kiakos, R.R. Davis, Christopher Tronrud, John A. Hartley, Alan Sielaff
Publikováno v:
Cancer Research. 70:3521-3521
Pyrrole (P)-Imidazole (I) containing polyamides are small synthetic molecules which can target predetermined DNA sequences with high affinity and modulate gene expression by interfering with the binding of transcription factors to DNA. As a model sys