Gastrin-Releasing Peptide Receptor Mediates Activation of the Epidermal Growth Factor Receptor in Lung Cancer Cells

Autor: Sufi Mary Thomas, Jennifer Rubin Grandis, Abbey L. Wentzel, William E. Gooding, Vivian Wai Yan Lui, Jill M. Siegfried

Publikováno v: Neoplasia: An International Journal for Oncology Research, Vol 7, Iss 4, Pp 426-431 (2005)

Gastrin-releasing peptide receptor (GRPR) and the epidermal growth factor receptor (EGFR) are expressed in several cancers including non-small cell lung carcinoma (NSCLC). Here we demonstrate the activation of EGFR by the GRPR ligand, gastrin-releasi

Externí odkaz: https://doaj.org/article/4209b4060d2d42699e1df238500e320b

List of Contributors

Autor: Jennifer E. Adair, Jahangir Ahmed, Ghassan Alusi, Doron Amit, Scott J. Antonia, Dominick L. Auci, David A. August, Rutger K. Balvers, Lajos Baranyi, Brian C. Beard, Sebastian Brennig, Elizabeth K. Broussard, Paul D. Bryson, Andrew P. Byrnes, Denise L. Cecil, Tim Chan, Charlie Comins, Christiaan R. de Vries, Robert S. DiPaola, Clemens M.F. Dirven, Mary L. Disis, Boro Dropulic, Heather Embree, Michael W. Epperly, Juan Fueyo, Toshiyoshi Fujiwara, Hua Fung, Emmanuel Gabriel, Vidya Ganapath, Stanton L. Gerson, Steven Gill, Michal Gilon, Joe Goldufsky, Candelaria Gomez-Manzano, Jennifer Rubin Grandis, Joel S. Greenberger, John W. Greiner, Maneesh Gujrati, James L. Gulley, Amin Hajitou, Kevin J. Harrington, Arash Hatefi, Loree C. Heller, Richard Heller, Akseli Hemminki, Otto Hemminki, Ronald B. Herberman, Daniel Herendeen, Abraham Hochberg, James W. Hodge, Gregory E. Holt, Ying Huang, Insoo Hyun, Hong Jiang, Shunsuke Kagawa, Zahra Karjoo, Howard Kaufman, Chien-Chih Ke, Hans-Peter Kiem, Jonathan Kimmelman, Sarah R. Klein, Shinji Kuroda, Seong Young Kwon, Nico Lachmann, Hermann Lage, Martine L.M. Lamfers, Edmund C. Lattime, Nicholas R. Lemoine, Jonathan Lewis, John B. Liao, Steven K. Libutti, Yuan Lin, Ren-Shyan Liu, Zheng-Rong Lu, Ravi A. Madan, Imad Matouk, Alan Melcher, Andrew D. Miller, Jung-Joon Min, Thomas Moritz, James J. Mulé, Atsushi Natsume, Nastasia Nianiaris, Michael I. Nishimura, Claudia Palena, Hardev Pandha, Jessica Pastoriza, Mary C. Pinder-Schenck, Sujan Piya, Elizabeth Poplin, John A. Puskas, Thomas Quinn, Ankit Rao, Jane S. Reese, Kate Relph, Juan J. Rojas, Yvonne Saenger, Jeffrey Schlom, Kevin Shannon, Shawna A. Shirley, Guy R. Simpson, Shanthi Sivendran, Vladimir Slepushkin, Sirirurg Songsivilai, Neil Steven, Sufi Mary Thomas, Steve H. Thorne, Kwong-Yok Tsang, Takashi Tsujiuchi, Toshihiko Wakabayashi, Pin Wang, Xinxin Wang, Yaohe Wang, Robert E. Weiss, Edward White, Yohsuke Yagawa, Teerapong Yata, Ming Yuan, Ziqiang Yuan

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::9859ecd7a8906dc1395cd68c9b25af0d
https://doi.org/10.1016/b978-0-12-394295-1.00046-9

Antiangiogenic therapy of head and neck squamous cell carcinoma by vascular endothelial growth factor antisense therapy

Autor: Frank, Riedel, Karl, Götte, Karl, Hörmann, Jennifer Rubin, Grandis

Publikováno v: Advances in oto-rhino-laryngology. 62

Angiogenesis is increased in various human cancers, including head and neck squamous cell carcinoma (HNSCC), and correlates with tumor progression and metastasis. Vascular endothelial growth factor (VEGF) has been shown to be a key regulator of angio

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::f9289d31bffdce0c2f6c4608329f6e54
https://pubmed.ncbi.nlm.nih.gov/15608422

Constitutive activation of Stat5b contributes to carcinogenesis in vivo

Autor: Sichuan, Xi, Qing, Zhang, William E, Gooding, Thomas E, Smithgall, Jennifer Rubin, Grandis

Publikováno v: Cancer research. 63(20)

The development of more effective prevention and treatment strategies for solid tumors is limited by an incomplete understanding of the critical growth pathways that are activated in carcinogenesis. Signal transducers and activators of transcription

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::1bd05192c32a315877c29a79c74d5773
https://pubmed.ncbi.nlm.nih.gov/14583472

Responsiveness to the retinoic acid receptor-selective retinoid LGD1550 correlates with abrogation of transforming growth factor alpha/epidermal growth factor receptor autocrine signaling in head and neck squamous carcinoma cells

Autor: Miriam, Lango, Abbey L, Wentzel, John I, Song, Sichuan, Xi, Daniel E, Johnson, William W, Lamph, Lori, Miller, Jennifer Rubin, Grandis

Publikováno v: Clinical cancer research : an official journal of the American Association for Cancer Research. 9(11)

The use of retinoids to prevent and/or treat cancers, including head and neck squamous cell carcinoma (HNSCC), has been limited by the development of resistance and unwanted side effects. Receptor-selective retinoids are potentially less toxic than n

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=pmid________::3eee87bf3fe7ffdc4cb7171526f6511d
https://pubmed.ncbi.nlm.nih.gov/14519647