Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jennifer Rubel"'
Autor:
Anthony B. El-Khoueiry, Paul Y. Song, Jennifer Rubel, Dorna Y. Pourang, Christa Raab, Gabriele Hintzen, Michael Emig, Pilar Nava-Parada
Publikováno v:
Journal of Clinical Oncology. 40:TPS2675-TPS2675
TPS2675 Background: Natural killer (NK) cells are a critical component of the innate immune system involved in the eradication of transformed cells via antibody-dependent cellular cytotoxicity (ADCC). For treatment of solid tumors autologous NK cell
Autor:
Andrei I. Holodny, Joshua Gaal, Jennifer Rubel, Julio Arevalo-Perez, Marc K. Rosenblum, Eli L. Diamond, Vaios Hatzoglou, Kyung K. Peck, Amanuel A. Kebede
Publikováno v:
Journal of Neuroimaging. 26:366-371
BACKGROUND AND PURPOSE Low-grade and anaplastic oligodendrogliomas are often difficult to differentiate on the basis of conventional MR imaging characteristics. Dynamic contrast-enhanced (DCE) MRI can assess tumor microvasculature and has demonstrate
Autor:
Hildegard Pfister, Jennifer Rubel, Susanne Lucae, Tanja Brückl, Torsten Klengel, Andreas Menke, Florian Holsboer, Elisabeth B. Binder, Manfred Uhr
Publikováno v:
Genes, Brain and Behavior. 12:289-296
The FK506 binding protein 51 or FKBP5 has been implicated in the regulation of glucocorticoid receptor (GR) sensitivity, and genetic variants in this gene have been associated with mood and anxiety disorders. GR resistance and associated stress hormo
Autor:
Kyung K. Peck, Luca Marinelli, Zhigang Zhang, Mehrnaz Jenabi, Weiji Shi, Jennifer Rubel, Marcel Prastawa, Sasan Karimi, John K. Lyo, Nicole Petrovich Brennan, Andrei I. Holodny, Ek Tsoon Tan, Jonathan I. Sperl, Robert J. Young, Xiaofeng Liu, Robin Fatovic
To compare compressed diffusion spectrum imaging (CS-DSI) with diffusion tensor imaging (DTI) in patients with intracranial masses. We hypothesized that CS-DSI would provide superior visualization of the motor and language tracts.We retrospectively a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cbc3c556275b87238f7b92eed651eafb
https://europepmc.org/articles/PMC5222773/
https://europepmc.org/articles/PMC5222773/
Autor:
Robert J. Young, Zhigang Zhang, Kyung K. Peck, Jennifer Rubel, Taylor Schneider, Antonio Omuro, Vaios Hatzoglou, Kaitlin M. Woo, T. Jonathan Yang, Gary A. Ulaner, Kathryn Beal, Igor T. Gavrilovic
BACKGROUND The aim of this study was to assess the effectiveness of fluorine-18 fluorodeoxyglucose (FDG) PET-CT and dynamic contrast-enhanced (DCE) MRI in differentiating tumor progression and radiation injury in patients with indeterminate enhancing
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::86e035eb938884b9287c155a5cf720a9
https://europepmc.org/articles/PMC4864262/
https://europepmc.org/articles/PMC4864262/
Autor:
Craig Nolan, Elizabeth A. Maher, Kimberly Straley, Andrei I. Holodny, Justin R. Cross, Samuel Briggs, Marc K. Rosenblum, Changho Choi, Jennifer Rubel, Ingo K. Mellinghoff, Sunitha B. Thakur, Ralph Noeske, Thomas Kaley, Philip H. Gutin, Lisa M. DeAngelis, Elena Pentsova, Jamie Tisnado, Jung Hun Oh, Robert J. Young, Dongwei Zhu, Katharine Yen, Carl Campos, Chuanhui Dong, Macarena I. de la Fuente, Alissa A. Thomas, Julio Arevalo-Perez, Antonio Omuro
Publikováno v:
Neuro-oncology. 18(2)
Background The majority of WHO grades II and III gliomas harbor a missense mutation in the metabolic gene isocitrate dehydrogenase (IDH) and accumulate the metabolite R-2-hydroxyglutarate (R-2HG). Prior studies showed that this metabolite can be dete
Autor:
Ulrike Naumann, Michel Mittelbronn, Patrick N. Harter, Anna-Eva Blank, Jennifer Rubel, Elena I. Ilina, Hugo Bastida Esteban
Publikováno v:
Translational Neuroscience. 4
Diffuse human gliomas constitute a group of most treatment-refractory tumors even if maximum treatment strategies including neurosurgical resection followed by combined radio-/chemotherapy are applied. In contrast to most other neoplasms, diffusely i
Autor:
Andrei I. Holodny, Joseph O. Deasy, Macarena I. de la Fuente, Jamie Tisnado, Robert J. Young, Justin R. Cross, Jennifer Rubel, Lisa M. DeAngelis, Samuel Briggs, Ingo K. Mellinghoff, Sunitha B. Thakur
Publikováno v:
Cancer Research. 75:1498-1498
The metabolic genes isocitrate dehydrogenase 1 (IDH1) or IDH2 are mutated in 70-80% of WHO grade II and III glioma. The mutant IDH enzyme gains a new function producing D-2-hydroxyglutarate (2-HG). 2-HG is a small molecule that accumulates in IDH mut
Autor:
Pei-Yu Kuo, Violetta V. Leshchenko, Samira Shahnaz, Venu K. Thirukonda, Weijia Zhang, Hearn Jay Cho, E. Premkumar Reddy, M. V. Ramana Reddy, Samir Parekh, Jennifer Rubel, Zewei Jiang, Deepak Perumal
Publikováno v:
Cancer Research. 74:1324-1324
Multiple Myeloma (MM) is an incurable malignancy of plasma cells afflicting over 21,000 patients and accounting for over 10,000 deaths in the US each year. It is characterized by recurrent chromosomal translocations resulting in the dysregulation of
Autor:
Kerry J. Ressler, Torsten Klengel, Divya Mehta, Monika Rex-Haffner, Elisabeth B. Binder, Andreas Menke, Bertram Müller-Myhsok, Kristina B. Mercer, Benno Pütz, Jennifer Rubel, Florian Holsboer, Mariya Gonik, Bekh Bradley
Publikováno v:
Archives of General Psychiatry. 68:901
Context: Polymorphisms in the gene encoding the glucocorticoid receptor (GR) regulating co-chaperone FKBP5 have been shown to alter GR sensitivity and are associated with an increased risk to develop posttraumatic stress disorder (PTSD). Objective: T