Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jennifer Roccisana"'
Autor:
Shaun K. Bremner, Rebecca Berends, Alexandra Kaupisch, Jennifer Roccisana, Calum Sutherland, Nia J. Bryant, Gwyn W. Gould
Publikováno v:
PeerJ, Vol 11, p e15630 (2023)
The ability of insulin to stimulate glucose transport in muscle and fat cells is mediated by the regulated delivery of intracellular vesicles containing glucose transporter-4 (GLUT4) to the plasma membrane, a process known to be defective in disease
Externí odkaz:
https://doaj.org/article/5831b38646e94901aae3fc6ac5066021
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-9 (2021)
Abstract Background The undergraduate five-year MBChB programme at the University of Glasgow has a high volume of pathology teaching integrated into the course. The ability to better understand what pathology is taught and when, so as to build a pict
Externí odkaz:
https://doaj.org/article/bb9ddcdc816a4a259873c533eba89d94
Publikováno v:
BMC Medical Education, Vol 21, Iss 1, Pp 1-9 (2021)
BMC Medical Education
BMC Medical Education
Background The undergraduate five-year MBChB programme at the University of Glasgow has a high volume of pathology teaching integrated into the course. The ability to better understand what pathology is taught and when, so as to build a picture of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::31f40ea4950ababdcdf3a1925e2cf432
https://doi.org/10.1186/s12909-021-02808-3
https://doi.org/10.1186/s12909-021-02808-3
Background The undergraduate five-year MBChB programme at the University of Glasgow has a high volume of pathology teaching integrated into the course. The ability to better understand what pathology is taught and when, so as to build a picture of th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f602250f9ba8e70ab003dfb5b28ba48f
https://doi.org/10.21203/rs.3.rs-106999/v1
https://doi.org/10.21203/rs.3.rs-106999/v1
Publikováno v:
Communicative & Integrative Biology
Insulin stimulates the delivery of glucose transporter-4 (GLUT4)-containing vesicles to the surface of adipocytes. Depletion of the Sec1/Munc18 protein mVps45 significantly abrogates insulin-stimulated glucose transport and GLUT4 translocation. Here
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d35a306f652b3ebda74484f544a89640
https://eprints.gla.ac.uk/191247/1/191247.pdf
https://eprints.gla.ac.uk/191247/1/191247.pdf
Autor:
Poornima Rao, Karen K. Takane, Rita Bottino, Jennifer Roccisana, Adolfo Garcia-Ocaña, Allan Z. Zhao, Massimo Trucco
Publikováno v:
Diabetes. 54:1664-1675
Akt is an important intracellular mediator of β-cell growth and survival in rodents. However, whether constitutive activation of Akt in human β-cells enhances the survival and function of transplanted islets is unknown. In the current study, we exa
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::c46d80ba7272e0c61eb3e0d8e8dab340
https://doi.org/10.2337/diabetes.54.6.1664
https://doi.org/10.2337/diabetes.54.6.1664
Autor:
Rupangi C. Vasavada, Poornima Rao, Jennifer Roccisana, Irene Cózar-Castellano, Adolfo Garcia-Ocaña
Publikováno v:
Expert Opinion on Biological Therapy. 4:507-518
Recent clinical studies have documented that human islet transplantation has the potential to replace pancreatic endocrine function in patients with type 1 diabetes. These studies have also highlighted an enormous shortage of human islets that impede
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a8ff02f31ab6302edde6615861995d86
https://doi.org/10.1517/14712598.4.4.507
https://doi.org/10.1517/14712598.4.4.507
Autor:
Noriaki Kawanabe, Hiroshi Kajiya, Jennifer Roccisana, Sakamuri V. Reddy, Masanori Koide, G. David Roodman
Publikováno v:
Journal of Biological Chemistry. 279:10500-10507
RANK Ligand (RANKL) is a critical osteoclastogenic factor that is expressed on stromal cells and osteoblasts. Most resorption stimuli induce osteoclast formation by modulating RANKL gene expression in marrow stromal/osteoblast cells. However, it is u
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e5e09b8186726962b35e1f928b3f6872
https://doi.org/10.1074/jbc.m303727200
https://doi.org/10.1074/jbc.m303727200
Publikováno v:
Journal of Bone and Mineral Research. 18:458-465
The osteoclast (OCL) is the primary bone resorbing cell. OCL formation and activity is regulated by local factors produced in the bone microenvironment. We recently identified OCL inhibitory peptide-1 (OIP-1/ hSca) as a novel inhibitor of OCL formati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0e97fd225a1018910abb3b3752e3e419
https://doi.org/10.1359/jbmr.2003.18.3.458
https://doi.org/10.1359/jbmr.2003.18.3.458
Publikováno v:
Molecular Biology of the Cell
Insulin stimulates glucose transport by delivering GLUT4 from a specialized storage compartment to the plasma membrane. Subcellular fractionation and an in vitro assay for GLUT4-storage vesicle formation show that the Sec1/Munc18 protein mVps45 is re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4b1d3705e07599dc968ed436ea52b901
https://pubmed.ncbi.nlm.nih.gov/23741049
https://pubmed.ncbi.nlm.nih.gov/23741049