Zobrazeno 1 - 10
of 11
pro vyhledávání: '"Jennifer Reineke Pohlhaus"'
Publikováno v:
Academic medicine : journal of the Association of American Medical Colleges. 91(8)
To measure diversity within the National Institutes of Health (NIH)-funded workforce. The authors use a relevant labor market perspective to more directly understand what the NIH can influence in terms of enhancing diversity through NIH policies.Usin
Publikováno v:
Academic Medicine. 86:759-767
Purpose The authors provide an analysis of sex differences in National Institutes of Health (NIH) award programs to inform potential initiatives for promoting diversity in the research workforce. Method In 2010, the authors retrieved data for NIH ext
Autor:
Francisco S. Sy, David M. Stoff, Jennifer Reineke Pohlhaus, John Ruffin, Nathaniel Stinson, Kyu Rhee, Irene Dankwa-Mullan
Publikováno v:
American Journal of Public Health. 100:S19-S24
Translational, transdisciplinary, and transformational research stands to become a paradigm-shifting mantra for research in health disparities. A windfall of research discoveries using these 3 approaches has increased our understanding of the health
Publikováno v:
Gene. 356:69-76
Nalidixic acid, the prototype antibacterial quinolone, induces the SOS response by a mechanism that requires the RecBCD nuclease/helicase. A key step inferred for this induction pathway is the conversion of a drug-induced gyrase cleavage complex into
Publikováno v:
Molecular Microbiology. 56:1416-1429
Antibacterial quinolones inhibit type II DNA topoisomerases by stabilizing covalent topoisomerase-DNA cleavage complexes, which are apparently transformed into double-stranded breaks by cellular processes such as replication. We used plasmid pBR322 a
Type II DNA topoisomerases are essential enzymes involved in processes such as DNA replication, chromosome segregation, and transcription (7, 26, 55). Many clinically important antibacterial and antitumor agents target type II topoisomerases by alter
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d3d98a27e4b91bc310e948872dc9ccb3
https://europepmc.org/articles/PMC2493257/
https://europepmc.org/articles/PMC2493257/
Publikováno v:
Methods in enzymology. 409
Replication forks can be stalled by tightly bound proteins, DNA damage, nucleotide deprivation, or defects in the replication machinery. It is now appreciated that processing of stalled replication forks is critical for completion of DNA replication
Publikováno v:
The Journal of biological chemistry. 280(5)
Eukaryotic type IA topoisomerases are important for the normal function of the cell, and in some cases essential for the organism, although their role in DNA metabolism remains to be elucidated. In this study, we cloned Drosophila melanogaster topois
Publikováno v:
Annals of Internal Medicine. 152:616
Publikováno v:
Nature. 453:1282-1282