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Autor:
Sandra Moreno-Mazza, Stuart Emanuel, Peter J. Connolly, Niranjan Pandey, Robert H. Gruninger, Lee M. Greenberger, Virna Borowski, Steven A. Middleton, Terry V. Hughes, Jennifer R. Story, Cheryl Napier, Jeannene Butler, Mary Adams, Beth A. Hollister, Catherine A. Rugg, Angel R. Fuentes‐Pesquera
Publikováno v:
Molecular Pharmacology. 73:338-348
JNJ-28871063 is a potent and highly selective pan-ErbB kinase inhibitor from a novel aminopyrimidine oxime structural class that blocks the proliferation of epidermal growth factor receptor (EGFR; ErbB1)- and ErbB2-overexpressing cells but does not a