Zobrazeno 1 - 10
of 70
pro vyhledávání: '"Jennifer R. Potts"'
Autor:
Caroline R. Pearson, Sarah N. Tindall, Reyme Herman, Huw T. Jenkins, Alex Bateman, Gavin H. Thomas, Jennifer R. Potts, Marjan W. Van der Woude
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
ABSTRACT Membrane bound acyltransferase-3 (AT3) domain-containing proteins are implicated in a wide range of carbohydrate O-acyl modifications, but their mechanism of action is largely unknown. O-antigen acetylation by AT3 domain-containing acetyltra
Externí odkaz:
https://doaj.org/article/6663fdadb8264093871da52c7411d220
Autor:
Karthik V. Rajasekar, Konrad Zdanowski, Jun Yan, Jonathan T. S. Hopper, Marie-Louise R. Francis, Colin Seepersad, Connor Sharp, Ludovic Pecqueur, Jörn M. Werner, Carol V. Robinson, Shabaz Mohammed, Jennifer R. Potts, Colin Kleanthous
Publikováno v:
Nature Communications, Vol 7, Iss 1, Pp 1-14 (2016)
Counteracting oxidative stress is essential in all organisms. Here, the authors outline a mechanism used by actinomycete bacteria in which oxidation of zinc-binding RsrA blocks its interaction with σR by sequestering hydrophobic residues used to bin
Externí odkaz:
https://doaj.org/article/c89d901e44ac441eb22442e5e5cd39b3
Autor:
Laura C. Clark, Kate E. Atkin, Fiona Whelan, Andrew S. Brentnall, Gemma Harris, Aisling M. Towell, Johan P. Turkenburg, Yan Liu, Ten Feizi, Samuel C. Griffiths, Joan A. Geoghegan, Jennifer R. Potts
Staphylococcus aureus and Staphylococcus epidermidis are frequently associated with medical device infections that involve establishment of a bacterial biofilm on the device surface. Staphylococcal surface proteins Aap, SasG, and Pls are members of t
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6f2eb7e8c4a424c63c4bb0e916418d50
http://hdl.handle.net/10044/1/102804
http://hdl.handle.net/10044/1/102804
Publikováno v:
Microbiology. 168
The acylation of sugars, most commonly via acetylation, is a widely used mechanism in bacteria that uses a simple chemical modification to confer useful traits. For structures like lipopolysaccharide, capsule and peptidoglycan, that function outside
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f90c01a10624760bf89e255cee3c2dbc
https://doi.org/10.1099/mic.0.001146
https://doi.org/10.1099/mic.0.001146
Autor:
Xiaowen Liang, Brandon L Garcia, Livia Visai, Sabitha Prabhakaran, Nicola A G Meenan, Jennifer R Potts, Martin J Humphries, Magnus Höök
Publikováno v:
PLoS ONE, Vol 11, Iss 7, p e0159118 (2016)
Adherence of microbes to host tissues is a hallmark of infectious disease and is often mediated by a class of adhesins termed MSCRAMMs (Microbial Surface Components Recognizing Adhesive Matrix Molecules). Numerous pathogens express MSCRAMMs that spec
Externí odkaz:
https://doaj.org/article/e09139c6c721485aab9313854adab1ab
Autor:
James W. B. Moir, Emanuele Paci, S.C. Griffiths, Huw T. Jenkins, Jennifer R. Potts, Alexander N. St John, Christoph G. Baumann, Aleix Lafita, James Alexander Hinett Gilburt, Clement Degut, Fiona Whelan, Michael J. Plevin, Alex Bateman
Changes at the cell surface enable bacteria to survive in dynamic environments, such as diverse niches of the human host. Here, we reveal “Periscope Proteins” as a widespread mechanism of bacterial surface alteration mediated through protein leng
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::f88f30ba202f14c837a0057192de86de
https://doi.org/10.1101/2020.12.24.424174
https://doi.org/10.1101/2020.12.24.424174
Autor:
Jennifer R. Potts, Alex Bateman, Reyme Herman, Caroline Pearson, Marjan W. van der Woude, Sarah Tindall, Huw T. Jenkins, Gavin H. Thomas
Publikováno v:
mBio, Vol 11, Iss 4 (2020)
mBio
mBio
Acyltransferase-3 (AT3) domain-containing membrane proteins are involved in O-acetylation of a diverse range of carbohydrates across all domains of life. In bacteria they are essential in processes including symbiosis, resistance to antimicrobials, a
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::592ebd0f46f5815306688911c98d73e4
https://doi.org/10.1128/mbio.01364-20
https://doi.org/10.1128/mbio.01364-20
Publikováno v:
PLoS ONE, Vol 6, Iss 4, p e18899 (2011)
Staphylococcus aureus is a commensal organism and a frequent cause of skin and soft tissue infections, which can progress to serious invasive disease. This bacterium uses its fibronectin binding proteins (FnBPs) to invade host cells and it has been h
Externí odkaz:
https://doaj.org/article/7a81b80270a64f36a3f84d05474ad8f9
Publikováno v:
PLoS Pathogens, Vol 6, Iss 6, p e1000964 (2010)
Entry of Staphylococcus aureus into the bloodstream can lead to metastatic abscess formation and infective endocarditis. Crucial to the development of both these conditions is the interaction of S. aureus with endothelial cells. In vivo and in vitro
Externí odkaz:
https://doaj.org/article/3924fbbbafef4fc0982c4d172936868a
Publikováno v:
PLoS ONE, Vol 4, Iss 4, p e5412 (2009)
BBK32 is a surface expressed lipoprotein and fibronectin (Fn)-binding microbial surface component recognizing adhesive matrix molecule (MSCRAMM) of Borrelia burgdorferi, the causative agent of Lyme disease. Previous studies from our group showed that
Externí odkaz:
https://doaj.org/article/39810508b8d944f5a5496e0bd1aa1e6f