Zobrazeno 1 - 10
of 10
pro vyhledávání: '"Jennifer R. Mastroianni"'
Publikováno v:
Antibiotics, Vol 3, Iss 4, Pp 493-508 (2014)
Small intestinal Paneth cells secrete a-defensin peptides, termed cryptdins (Crps) in mice, into the intestinal lumen, where they confer immunity to oral infections and define the composition of the ileal microbiota. In these studies, facultative bac
Externí odkaz:
https://doaj.org/article/1d77f86cbc024e9f87dead667f7ef423
Autor:
Eduardo R. Cobo, Ravi Holani, France Moreau, Kiminori Nakamura, Tokiyoshi Ayabe, Jennifer R. Mastroianni, Yoshihiro Eriguchi, Andre Ouellette, Kris Chadee
Enteric α-defensins, termed cryptdins (Crps) in mice, and lysozymes secreted by Paneth cells contribute to innate host defense in the ileum. Antimicrobial factors, including lysozymes and β-defensins, are often embedded in luminal glycosylated colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0ad2af8746730d8c077b839fb38acf56
https://europepmc.org/articles/PMC6204739/
https://europepmc.org/articles/PMC6204739/
Autor:
Eduardo R. Cobo, Ravi Holani, France Moreau, Kiminori Nakamura, Tokiyoshi Ayabe, Jennifer R. Mastroianni, Yoshihiro Eriguchi, Andre Ouellette, Kris Chadee
Publikováno v:
Infection and Immunity. 86
Enteric α-defensins, termed cryptdins (Crps) in mice, and lysozymes secreted by Paneth cells contribute to innate host defense in the ileum. Antimicrobial factors, including lysozymes and β-defensins, are often embedded in luminal glycosylated colo
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::13ade07ebde56403a83e4b7861146331
https://doi.org/10.1128/iai.00208-18
https://doi.org/10.1128/iai.00208-18
Autor:
Diana Lam, Vladimir E. Diaz-Ochoa, Mauro Cerasi, Jennifer R. Mastroianni, Celia W. Goulding, Christina M. Jacobo, Carlin S. Lee, Subodh Rathi, Nicholas Chim, Sean Paul Nuccio, Walter J. Chazin, Manuela Raffatellu, Suzi Klaus, Eric P. Skaar, Robert Edwards, Janet Z. Liu, Andrea Battistoni, Andre J. Ouellette, Judith Behnsen
Publikováno v:
Cell host & microbe, vol 19, iss 6
Neutrophils hinder bacterial growth by a variety of antimicrobial mechanisms, including the production of reactive oxygen species and the secretion of proteins that sequester nutrients essential to microbes. A major player in this process is calprote
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::02170e1cf87744eb18f5a0eef0948f5d
http://hdl.handle.net/2108/150507
http://hdl.handle.net/2108/150507
Autor:
Nita H. Salzman, Jessica K. Costales, Jennifer Zaksheske, Michael E. Selsted, Jennifer R. Mastroianni, Andre J. Ouellette
Publikováno v:
Journal of Biological Chemistry. 287:11205-11212
Paneth cell α-defensins mediate host defense and homeostasis at the intestinal mucosal surface. In mice, matrix metalloproteinase-7 (MMP7) converts inactive pro-α-defensins (proCrps) to bactericidal forms by proteolysis at specific proregion cleava
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2d46062c514c06b47b0878d4b6e9b1d7
https://doi.org/10.1074/jbc.m111.333559
https://doi.org/10.1074/jbc.m111.333559
Autor:
Bogi Andersen, Kambiz Afrasiabi, Diana Dizon, Steven M. Lipkin, Mikhail Geyfman, Robert Edwards, Fang Zhao, Andre J. Ouellette, Jennifer R. Mastroianni
Publikováno v:
Developmental Biology. 338:270-279
Anterior Gradient 2 (AGR2) is a protein disulfide isomerase that plays important roles in diverse processes in multiple cell lineages as a developmental regulator, survival factor and susceptibility gene for inflammatory bowel disease. Here, we show
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9c1e5c22e688c204e4e8f044ca2662e5
https://doi.org/10.1016/j.ydbio.2009.12.008
https://doi.org/10.1016/j.ydbio.2009.12.008
Publikováno v:
Journal of Biological Chemistry. 284:27848-27856
Paneth cells are a secretory epithelial lineage that release dense core granules rich in host defense peptides and proteins from the base of small intestinal crypts. Enteric α-defensins, termed cryptdins (Crps) in mice, are highly abundant in Paneth
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::58f10e8446247577ad5dffff0a919693
https://doi.org/10.1074/jbc.m109.050773
https://doi.org/10.1074/jbc.m109.050773
Publikováno v:
The FASEB Journal. 24
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::db52fbaface1f5d8dc160b696777b007
https://doi.org/10.1096/fasebj.24.1_supplement.952.7
https://doi.org/10.1096/fasebj.24.1_supplement.952.7
Publikováno v:
Methods in molecular biology (Clifton, N.J.). 618
Recombinant expression of alpha-defensins can be obtained at efficient levels in Escherichia coli. Amplified alpha-defensin or pro-alpha-defensin coding cDNA sequences are cloned directionally between EcoRI and SalI sites of the pET-28a expression ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::f325c420f4ab35e1532841d97689923c
https://pubmed.ncbi.nlm.nih.gov/20094857
https://pubmed.ncbi.nlm.nih.gov/20094857
Expression and Purification of Recombinant α-Defensins and α-Defensin Precursors in Escherichia coli
Publikováno v:
Methods in Molecular Biology ISBN: 9781607615934
Recombinant expression of alpha-defensins can be obtained at efficient levels in Escherichia coli. Amplified alpha-defensin or pro-alpha-defensin coding cDNA sequences are cloned directionally between EcoRI and SalI sites of the pET-28a expression ve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::46bbcec4218b996e3480648e8bcc509b
https://doi.org/10.1007/978-1-60761-594-1_4
https://doi.org/10.1007/978-1-60761-594-1_4