Zobrazeno 1 - 10
of 12
pro vyhledávání: '"Jennifer R. Hurley"'
Autor:
Abdul Q Sheikh, Jennifer R Hurley, Wei Huang, Toloo Taghian, Andrei Kogan, Hongkwan Cho, Yigang Wang, Daria A Narmoneva
Publikováno v:
PLoS ONE, Vol 7, Iss 5, p e36840 (2012)
Diabetic cardiomyopathy (DCM) is a diabetic complication, which results in myocardial dysfunction independent of other etiological factors. Abnormal intracellular calcium ([Ca(2+)](i)) homeostasis has been implicated in DCM and may precede clinical m
Externí odkaz:
https://doaj.org/article/b1df6052fb4446c88a61bed77e0fd405
Autor:
Abdul Q. Sheikh, Robert B. Hinton, Wei Huang, Jennifer R. Hurley, Courtney Kuesel, Toloo Taghian, Daria A. Narmoneva, Yigang Wang
Publikováno v:
American Journal of Physiology-Cell Physiology. 306:C768-C778
Diabetes-induced cardiomyopathy is characterized by cardiac remodeling, fibrosis, and endothelial dysfunction, with no treatment options currently available. Hyperglycemic memory by endothelial cells may play the key role in microvascular complicatio
Publikováno v:
Cellular and Molecular Bioengineering. 5:173-183
Overcoming the effects of hyperglycemic conditions on matrix remodeling by cardiac fibroblasts represents a novel therapeutic approach to stimulate regeneration of cardiac tissue in the context of diabetes. The purpose of this study was to investigat
Autor:
Daria A. Narmoneva, Timothy M. Crombleholme, Hongkwan Cho, Sundeep G. Keswani, Swathi Balaji, Abdul Q. Sheikh, Jennifer R. Hurley
Objective: The effect of chronic hyperglycemic exposure on endothelial cell (EC) phenotype, impaired wound neovascularization, and healing is not completely understood. The hypotheses are: 1) chronic exposure to diabetic conditions in vivo impairs th
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::fe45d239e4c94605024bed68eee99d62
https://europepmc.org/articles/PMC4217038/
https://europepmc.org/articles/PMC4217038/
Autor:
Toloo Taghian, Daria A. Narmoneva, Abdul Q. Sheikh, Jennifer R. Hurley, Andrei Kogan, Yigang Wang, Wei Huang, Hongkwan Cho
Publikováno v:
PLoS ONE
PLoS ONE, Vol 7, Iss 5, p e36840 (2012)
PLoS ONE, Vol 7, Iss 5, p e36840 (2012)
Diabetic cardiomyopathy (DCM) is a diabetic complication, which results in myocardial dysfunction independent of other etiological factors. Abnormal intracellular calcium ([Ca(2+)](i)) homeostasis has been implicated in DCM and may precede clinical m
Autor:
Meredith Beckenhaupt, Cameron Ingram, Andrew Mutchler, Jennifer R. Hurley, Abdul Q. Sheikh, Daria A. Narmoneva
Publikováno v:
ASME 2011 Summer Bioengineering Conference, Parts A and B.
Diabetes is a serious problem in the United States, afflicting 7.8% of the population with annual medical costs estimated at $116B in 2007 (1). Diabetic cardiomyopathy (DCM) is a cardiovascular complication of diabetes resulting in pathological alter
Publikováno v:
ASME 2011 Summer Bioengineering Conference, Parts A and B.
Diabetic cardiomyopathy (DCM) is a serious diabetes-associated complication that results in myocardial dysfunction independent of other etiological factors [1]. Pathological alterations to the myocardium associated with DCM include circulatory defect
Autor:
Joel H. Collier, Jennifer R. Hurley, Daria A. Narmoneva, Abdul Q. Sheikh, Hongkwan Cho, Timothy M. Crombleholme, Ye F. Tian, Swathi Balaji
Publikováno v:
Acta biomaterialia. 8(1)
RAD16-II peptide nanofibers are promising for vascular tissue engineering and were shown to enhance angiogenesis in vitro and in vivo, although the mechanism remains unknown. We hypothesized that the pro-angiogenic effect of RAD16-II results from low
Publikováno v:
Journal of Bioengineering & Biomedical Science.
Publikováno v:
American journal of physiology. Cell physiology. 299(2)
Interactions between endothelial and stromal cells are important for vascularization of regenerating tissue. Fibroblasts (FBs) are responsible for expression of angiogenic growth factors and matrix metalloproteinases, as well as collagen deposition a