Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer R. Ferrer"'
Publikováno v:
Bioconjugate Chemistry. 30:944-951
Liposomal spherical nucleic acids (LSNAs) are a class of nanomaterial used broadly for biomedical applications. Their intrinsic capacity to rapidly enter cells and engage cell surface and intracellular ligands stems from their unique three-dimensiona
Autor:
Xin Yi Yeap, Chad A. Mirkin, Andrew J. Sinegra, David Ivancic, Jason A. Wertheim, Jiao Jing Wang, Jennifer R. Ferrer, Zheng Jenny Zhang, Longhui Qiu
Publikováno v:
ACS nano. 14(2)
Spherical nucleic acids (SNAs) are a class of nanomaterials with a structure defined by a radial distribution of densely packed, short DNA or RNA sequences around a nanoparticle core. This structure allows SNAs to rapidly enter mammalian cells, prote
The effects of spherical nucleic acid (SNA) gold nanoparticle conjugates on the activation of macrophages in vitro and release of cytokines in vivo were explored. Herein, we show that G-quadruplexes, the formation of which is enhanced on gold nanopar
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::99a1c4fac76b00ae24ec6a56705bc9c5
https://europepmc.org/articles/PMC6894393/
https://europepmc.org/articles/PMC6894393/
Publikováno v:
Bioconjugate Chemistry
Two synthetic approaches that allow one to control PEG content within spherical nucleic acids (SNAs) have been developed. One approach begins with RNA-modified gold nanoparticles followed by a backfill of PEG 2K alkanethiols, and the other involves c
Autor:
Chad A. Mirkin, Stacey N. Barnaby, Alyssa B. Chinen, Chenxia M. Guan, Timothy J. Merkel, Jennifer R. Ferrer
Publikováno v:
Chemical Reviews. 115:10530-10574
1.1. Cancer and Early Detection Cancer is the second most common cause of death in the United States, trailing only heart disease in incidence. Despite significant worldwide investment in research, cancer remains responsible for 1 in 4 deaths in deve
Publikováno v:
Current transplantation reports. 2(2)
The current standard of care for end stage liver disease is orthotopic liver transplantation (OLT). Through improvement in surgical techniques, immunosuppression, and general medical care, liver transplantation has become an effective treatment over