Zobrazeno 1 - 6
of 6
pro vyhledávání: '"Jennifer R Kimbrough"'
Publikováno v:
Organic Letters. 21:10048-10051
A chemical synthesis of the major human metabolite of prostaglandin D2, tricyclic-PGDM, is described. The synthetic route starts from iodocyclopentenone 1 (available from cyclopentadiene in 6 steps) and requires 13 synthetic transformations. The synt
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d6a84750fbfdffa5ab33f7dfb5e0a2b2
https://doi.org/10.1021/acs.orglett.9b03983
https://doi.org/10.1021/acs.orglett.9b03983
Autor:
William C. K. Pomerantz, Anand Divakaran, Prakriti Kalra, Jonathan Solberg, Huarui Cui, Jon E. Hawkinson, Kristen John, Anil K. Pandey, Logan McGraw, Jennifer R. Kimbrough
Publikováno v:
ACS Chem Biol
Multidomain bromodomain-containing proteins regulate gene expression via chromatin binding, interactions with the transcriptional machinery, and by recruiting enzymatic activity. Selective inhibition of members of the bromodomain and extra-terminal (
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::151478fda9bef7e98a337945fb84423b
https://europepmc.org/articles/PMC8185897/
https://europepmc.org/articles/PMC8185897/
Autor:
Jennifer R, Kimbrough, Somnath, Jana, Kwangho, Kim, Alexander, Allweil, John A, Oates, Ginger L, Milne, Gary A, Sulikowski
Publikováno v:
Tetrahedron Lett
Prostaglandin E(2) is produced in response to inflammation, often associated with human disease. As prostaglandins are rapidly metabolized, quantification of end urinary metabolites depend on chemical synthesis of isotopically labeled standards to su
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::2ff66d6aa47e72f3229b3c85e869da14
https://pubmed.ncbi.nlm.nih.gov/32523235
https://pubmed.ncbi.nlm.nih.gov/32523235
Autor:
Jennifer R Kimbrough, Jorden A. Johnson, Steven E. Kirberger, Anil K. Pandey, William C. K. Pomerantz, Danika K. D. Partridge
Publikováno v:
Organic Letters. 22:5271-5272
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::173819c7e978044c4ea4329af2e6d201
https://doi.org/10.1021/acs.orglett.0c01848
https://doi.org/10.1021/acs.orglett.0c01848
Publikováno v:
Organic letters. 21(24)
A chemical synthesis of the major human metabolite of prostaglandin D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::7b040b2eac3b0dbb651b50f30dbcf571
https://pubmed.ncbi.nlm.nih.gov/31799855
https://pubmed.ncbi.nlm.nih.gov/31799855
Autor:
Somnath Jana, Gary A. Sulikowski, Alexander Allweil, Jennifer R Kimbrough, Kwangho Kim, Ginger L. Milne, John A. Oates
Publikováno v:
Tetrahedron Letters. 61:151922
Prostaglandin E2 is produced in response to inflammation, often associated with human disease. As prostaglandins are rapidly metabolized, quantification of end urinary metabolites depend on chemical synthesis of isotopically labeled standards to supp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::051846fb7ac822df083cb6b56a9815a9
https://doi.org/10.1016/j.tetlet.2020.151922
https://doi.org/10.1016/j.tetlet.2020.151922