Zobrazeno 1 - 5
of 5
pro vyhledávání: '"Jennifer R Fang"'
Publikováno v:
Molecular Systems Biology, Vol 16, Iss 7, Pp 1-12 (2020)
Abstract Programmable gene activation enables fine‐tuned regulation of endogenous and synthetic gene circuits to control cellular behavior. While CRISPR‐Cas‐mediated gene activation has been extensively developed for eukaryotic systems, similar
Externí odkaz:
https://doaj.org/article/c87afd62f5c84cce933bd0ad4443b0c0
Autor:
Ashwin Ajith, Kenza Mamouni, Daniel D. Horuzsko, Abu Musa, Amiran K. Dzutsev, Jennifer R. Fang, Ahmed Chadli, Xingguo Zhu, Iryna Lebedyeva, Giorgio Trinchieri, Anatolij Horuzsko
Publikováno v:
The Journal of Clinical Investigation, Vol 133, Iss 21 (2023)
The triggering receptor expressed on myeloid cell 1 (TREM1) plays a critical role in development of chronic inflammatory disorders and the inflamed tumor microenvironment (TME) associated with most solid tumors. We examined whether loss of TREM1 sign
Externí odkaz:
https://doaj.org/article/5bb71203ab174a6d97240f62410448ca
Autor:
Ekaterina K. Koltsova, Sergei I. Grivennikov, Jonathan A. Hill, Giorgio Trinchieri, Amiran K. Dzutsev, Kerry S. Campbell, Xin Wei Wang, John Stagg, David L. Wiest, Andrew V. Kossenkov, Yin Fei Tan, Petr Makhov, Svetlana Khoziainova, Anastasiia Marchenko, Dmitry Zhigarev, Simon Turcotte, Isabelle Cousineau, Aliia R. Fatkhullina, Elizaveta K. Titerina, Ricard Masia, Kerry F. White, Manhsin Hung, Matthew Rausch, Iuliia O. Peshkova, Jennifer R. Fang, Aleksandra M. Mazitova, Turan Aghayev
Although inflammatory mechanisms driving hepatocellular carcinoma (HCC) have been proposed, the regulators of anticancer immunity in HCC remain poorly understood. We found that IL27 receptor (IL27R) signaling promotes HCC development in vivo. High IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::0488eaf43d501ff25edc4bae4c3d2bba
https://doi.org/10.1158/2159-8290.c.6549593.v1
https://doi.org/10.1158/2159-8290.c.6549593.v1
Autor:
Ekaterina K. Koltsova, Sergei I. Grivennikov, Jonathan A. Hill, Giorgio Trinchieri, Amiran K. Dzutsev, Kerry S. Campbell, Xin Wei Wang, John Stagg, David L. Wiest, Andrew V. Kossenkov, Yin Fei Tan, Petr Makhov, Svetlana Khoziainova, Anastasiia Marchenko, Dmitry Zhigarev, Simon Turcotte, Isabelle Cousineau, Aliia R. Fatkhullina, Elizaveta K. Titerina, Ricard Masia, Kerry F. White, Manhsin Hung, Matthew Rausch, Iuliia O. Peshkova, Jennifer R. Fang, Aleksandra M. Mazitova, Turan Aghayev
Supplementary Data from IL27 Signaling Serves as an Immunologic Checkpoint for Innate Cytotoxic Cells to Promote Hepatocellular Carcinoma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::6efd13a825c7040a930bdf2b3cbab6b2
https://doi.org/10.1158/2159-8290.22541261.v1
https://doi.org/10.1158/2159-8290.22541261.v1
Autor:
Turan Aghayev, Aleksandra M. Mazitova, Jennifer R. Fang, Iuliia O. Peshkova, Matthew Rausch, Manhsin Hung, Kerry F. White, Ricard Masia, Elizaveta K. Titerina, Aliia R. Fatkhullina, Isabelle Cousineau, Simon Turcotte, Dmitry Zhigarev, Anastasiia Marchenko, Svetlana Khoziainova, Petr Makhov, Yin Fei Tan, Andrew V. Kossenkov, David L. Wiest, John Stagg, Xin Wei Wang, Kerry S. Campbell, Amiran K. Dzutsev, Giorgio Trinchieri, Jonathan A. Hill, Sergei I. Grivennikov, Ekaterina K. Koltsova
Publikováno v:
Cancer Discov
Although inflammatory mechanisms driving hepatocellular carcinoma (HCC) have been proposed, the regulators of anticancer immunity in HCC remain poorly understood. We found that IL27 receptor (IL27R) signaling promotes HCC development in vivo. High IL
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::29b42bb7609baab1cde84e56f1ce8cef
https://doi.org/10.1158/2159-8290.cd-20-1628
https://doi.org/10.1158/2159-8290.cd-20-1628