Zobrazeno 1 - 10
of 781
pro vyhledávání: '"Jennifer R Brown"'
Autor:
Laura Ondrisova, Vaclav Seda, Eva Hoferkova, Giorgia Chiodin, Krystof Hlavac, Lenka Kostalova, Daniel Filip, Pedro Faria Zeni, Anna Panovska, Karla Plevova, Sarka Pospisilova, Martin Simkovic, Filip Vrbacky, Daniel Lysak, Stacey M. Fernandes, Matthew S. Davids, Alba Maiques-Diaz, Stella Charalampopoulou, Jose I Martin-Subero, Jennifer R Brown, Michael Doubek, Francesco Forconi, Jiri Mayer, Marek Mraz
Publikováno v:
HemaSphere, Vol 7, p e8228434 (2023)
Externí odkaz:
https://doaj.org/article/d170c389beac401f8b76921cc6daacb9
Autor:
Dennis Jinglun Yuan, Shuai Shao, Joanne H Lee, Stacey M Fernandes, Jennifer R Brown, Lance C Kam
Publikováno v:
Journal of Clinical and Translational Science, Vol 4, Pp 15-15 (2020)
OBJECTIVES/GOALS: Utilize polymer-based fiber scaffolds and machine learning methods applied to patient biomarker data to enhance and personalize T cell expansion and production for T cell therapy in chronic lymphocytic leukemia. METHODS/STUDY POPULA
Externí odkaz:
https://doaj.org/article/0125acbaae754e69a86ddc6c95cb1467
Autor:
Jennifer R Brown
Publikováno v:
Haematologica, Vol 103, Iss 7 (2018)
Externí odkaz:
https://doaj.org/article/6ebce3037acf4e65b25a38cdb55217e4
Autor:
Caroline Holm Nørgaard, Lasse Hjort Jakobsen, Andrew J Gentles, Karen Dybkær, Tarec Christoffer El-Galaly, Julie Støve Bødker, Alexander Schmitz, Preben Johansen, Tobias Herold, Karsten Spiekermann, Jennifer R Brown, Josephine L Klitgaard, Hans Erik Johnsen, Martin Bøgsted
Publikováno v:
PLoS ONE, Vol 13, Iss 3, p e0193249 (2018)
Diagnostic and prognostic evaluation of chronic lymphocytic leukemia (CLL) involves blood cell counts, immunophenotyping, IgVH mutation status, and cytogenetic analyses. We generated B-cell associated gene-signatures (BAGS) based on six naturally occ
Externí odkaz:
https://doaj.org/article/54d6f02da4e545279292e8d9f730b34d
Autor:
Roberta S. Azevedo, Francesca Morelli, Kiyomi Mashima, Rayan Fardoun, Svitlana Tyekucheva, Stacey Fernandes, Samantha Shupe, Marissa Terra, Anisha Patel, Matthew S. Davids, Joseph Yu, Jennifer R. Brown
Publikováno v:
Haematologica, Vol 999, Iss 1 (2024)
Chronic lymphocytic leukemia (CLL) patients have an increased risk of secondary cancers, along with predisposition to CLL in their relatives. We have previously identified germline ATM variants as associated with CLL risk; here, we present their impa
Externí odkaz:
https://doaj.org/article/97a85dd3b87e4eada3214a8ce2c22660
Autor:
Cody Paiva, J Claire Godbersen, Ryan S Soderquist, Taylor Rowland, Sumner Kilmarx, Stephen E Spurgeon, Jennifer R Brown, Sreesha P Srinivasa, Alexey V Danilov
Publikováno v:
PLoS ONE, Vol 10, Iss 11, p e0143685 (2015)
CDK (cyclin-dependent kinase) inhibitors have shown remarkable activity in CLL, where its efficacy has been linked to inhibition of the transcriptional CDKs (7 and 9) and deregulation of RNA polymerase and short-lived pro-survival proteins such as MC
Externí odkaz:
https://doaj.org/article/76cdc642921945679fd81474213b76e4
Autor:
Justin Rendleman, Yevgeniy Antipin, Boris Reva, Christina Adaniel, Jennifer A Przybylo, Ana Dutra-Clarke, Nichole Hansen, Adriana Heguy, Kety Huberman, Laetitia Borsu, Ora Paltiel, Dina Ben-Yehuda, Jennifer R Brown, Arnold S Freedman, Chris Sander, Andrew Zelenetz, Robert J Klein, Yongzhao Shao, Mortimer Lacher, Joseph Vijai, Kenneth Offit, Tomas Kirchhoff
Publikováno v:
PLoS ONE, Vol 9, Iss 7, p e101685 (2014)
Molecular and genetic evidence suggests that DNA repair pathways may contribute to lymphoma susceptibility. Several studies have examined the association of DNA repair genes with lymphoma risk, but the findings from these reports have been inconsiste
Externí odkaz:
https://doaj.org/article/3f64b33497e7444c8525efdd3f910822
Autor:
Shuqiang Li, Howell F Moffett, Jun Lu, Lillian Werner, Hao Zhang, Jerome Ritz, Donna Neuberg, Kai W Wucherpfennig, Jennifer R Brown, Carl D Novina
Publikováno v:
PLoS ONE, Vol 6, Iss 3, p e16956 (2011)
Chronic lymphocytic leukemia (CLL) is thought to be a disease of resting lymphocytes. However, recent data suggest that CLL cells may more closely resemble activated B cells. Using microRNA (miRNA) expression profiling of highly-enriched CLL cells fr
Externí odkaz:
https://doaj.org/article/2ef6590ef52f4fd3b983ba2328087aef
Autor:
Katrine Melvold, Mariaserena Giliberto, Linda Karlsen, Pilar Ayuda‐Durán, Robert Hanes, Toril Holien, Jorrit Enserink, Jennifer R. Brown, Geir E. Tjønnfjord, Kjetil Taskén, Sigrid S. Skånland
Publikováno v:
Molecular Oncology, Vol 16, Iss 5, Pp 1153-1170 (2022)
Most patients with chronic lymphocytic leukemia (CLL) initially respond to targeted therapies, but eventually relapse and develop resistance. Novel treatment strategies are therefore needed to improve patient outcomes. Here, we performed direct drug
Externí odkaz:
https://doaj.org/article/67352beffad14b0ba011733748ab3689
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
Externí odkaz:
https://doaj.org/article/bf2d084e6cc141d69a489462362e6b57