Zobrazeno 1 - 10
of 56
pro vyhledávání: '"Jennifer R Berman"'
Autor:
Gregory E Alexander, Wendy Lin, Fabian E Ortega, Madhuvanthi Ramaiah, Byoungsok Jung, Lijuan Ji, Ekaterina Revenkova, Payal Shah, Christian Croisetiere, Jennifer R Berman, Lane Eubank, Gunjan Naik, Jacqueline Brooks, Andrea Mich, Seyedmehdi Shojaee, Neda Ronaghi, Hemanshi Chawla, Xinyi Hou, Qinwen Liu, Christopher-James A V Yakym, Patriss Wais Moradi, Meredith Halks-Miller, Alexander M Aravanis, Sonya Parpart-Li, Nathan Hunkapiller
Publikováno v:
PLoS ONE, Vol 18, Iss 4, p e0283001 (2023)
The analytical validation is reported for a targeted methylation-based cell-free DNA multi-cancer early detection test designed to detect cancer and predict the cancer signal origin (tissue of origin). A machine-learning classifier was used to analyz
Externí odkaz:
https://doaj.org/article/dd8363d94bd1437795386bee9e3165cc
Publikováno v:
PLoS ONE, Vol 11, Iss 4, p e0153901 (2016)
The rapid adoption of gene editing tools such as CRISPRs and TALENs for research and eventually therapeutics necessitates assays that can rapidly detect and quantitate the desired alterations. Currently, the most commonly used assay employs "mismatch
Externí odkaz:
https://doaj.org/article/98952949b49948dc86633ca2daf847cb
Autor:
Wei Yang, Dawne N Shelton, Jennifer R Berman, Bin Zhang, Samantha Cooper, Svilen Tzonev, Eli Hefner, John F Regan
Publikováno v:
BioTechniques, Vol 58, Iss 5, Pp 270-271 (2015)
Targeted therapies in many cancers have allowed unprecedented progress in the treatment of disease. However, routine implementation of genomic testing is constrained due to: 1) limited amounts of sample (pg–ng range) per biological specimen, 2) dia
Externí odkaz:
https://doaj.org/article/e9fdaeb8d82d4bacaaecd7be96db2490
Autor:
Tracy M Yamawaki, Jennifer R Berman, Monika Suchanek-Kavipurapu, Mark McCormick, Marta Maria Gaglia, Seung-Jae Lee, Cynthia Kenyon
Publikováno v:
PLoS Biology, Vol 8, Iss 8 (2010)
In Caenorhabditis elegans and Drosophila melanogaster, removing the germline precursor cells increases lifespan. In worms, and possibly also in flies, this lifespan extension requires the presence of somatic reproductive tissues. How the somatic gona
Externí odkaz:
https://doaj.org/article/0959b53d44c64789b25221f3b32f00e1
Publikováno v:
Current Sexual Health Reports. 13:45-53
There is a growing body of evidence-based research in the area of female sexual arousal that has led to improved understanding of the female sexual arousal response and the development of FDA-approved treatments for female sexual dysfunction. The pur
Publikováno v:
Current Sexual Health Reports. 11:44-51
To examine the peer-reviewed publications on the topic of female cosmetic genital surgery (FCGS) and discuss recent trends, the factors motivating patients to request these procedures, and the controversy surrounding them. In studies with the primary
Autor:
Steven A. McCarroll, Jennifer R. Berman, Giulio Genovese, Seva Kashin, Linda M Boettger, Vanessa Van Doren, Robert E. Handsaker
Publikováno v:
Nature genetics
Thousands of genome segments appear to be present in widely varying copy number in different human genomes. We developed ways to use increasingly abundant whole genome sequence data to identify the copy numbers, alleles and haplotypes present at most
Autor:
Claudia Litterst, Adam Lowe, Geoffrey P. McDermott, Yann Jouvenot, Pramod Walse, Pallavi Shah, Leanne Javier, Benjamin J. Hindson, Shenglong Wang, Thomas H. Cauly, Eli Hefner, John F. Regan, Svilen Tzonev, Luc J. Bousse, David P. Stumbo, Keith Hamby, Paul Wyatt, Timothy P. Brackbill, Tina C. Legler, Jennifer R. Berman, Yunfeng Ling, Amy L. Hiddessen, Chunxiao Han, Josephine Wong, Niels Klitgord, Samuel H. Marrs, Adam Bemis, George Karlin-Neumann, Viresh P. Patel, Ryan T. Koehler, Erin R. Steenblock, Dianna Maar, David Sally, Duc Do, Theresa Dinio, Christopher Hindson, Shawn Hodges, George Carman
Publikováno v:
Analytical Chemistry. 85:11619-11627
Two years ago, we described the first droplet digital PCR (ddPCR) system aimed at empowering all researchers with a tool that removes the substantial uncertainties associated with using the analogue standard, quantitative real-time PCR (qPCR). This s
Autor:
Dana Carroll, Dario Boffelli, Seok Jin Heo, Donald B. Kohn, Tianjiao Wang, Jacob E. Corn, Jennifer R. Berman, Mark A. DeWitt, Mark C. Walters, Therese Mitros, David I. K. Martin, Fabrizia Urbinati, Wendy Magis, Denise P. Muñoz, Nicolas Bray
Publikováno v:
Science Translational Medicine. 8
Genetic diseases of blood cells are prime candidates for treatment through ex vivo gene editing of CD34+ hematopoietic stem/progenitor cells (HSPCs), and a variety of technologies have been proposed to treat these disorders. Sickle Cell Disease (SCD)
Autor:
Denise P. Muñoz, Nicolas Bray, Fabrizia Urbinati, Mark C. Walters, Jacob E. Corn, David Martin, Wendy Magis, Dana Carroll, Tianjiao Wang, Donald B. Kohn, Jennifer R. Berman, Mark A. DeWitt
Sickle Cell Disease (SCD) is a serious recessive genetic disorder caused by a single nucleotide polymorphism (SNP) in the β-globin gene (HBB). Sickle hemoglobin polymerizes within red blood cells (RBCs), causing them to adopt an elongated "sickle" s
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e795ac7ea9e6fa7bf6ef86a10a9588a4