Zobrazeno 1 - 10
of 79
pro vyhledávání: '"Jennifer Q. Zhang"'
Autor:
Ferdinand Rossi, Mengyuan Liu, Andrew Tieniber, Mark S. Etherington, Andrew Hanna, Gerardo A. Vitiello, Nesteene J. Param, Kevin Do, Laura Wang, Cristina R. Antonescu, Shan Zeng, Jennifer Q. Zhang, Ronald P. DeMatteo
Publikováno v:
Clinical Cancer Research. 29:2144-2157
Purpose: To create an in vivo model of PDGFRA D842V-mutant gastrointestinal stromal tumor (GIST) and identify the mechanism of tumor persistence following avapritinib therapy. Experimental Design: We created a patient-derived xenograft (PDX) of PDGFR
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::fed41f74cb824ec4a2f1cda09e49008f
https://doi.org/10.1158/1078-0432.ccr-22-0533
https://doi.org/10.1158/1078-0432.ccr-22-0533
Autor:
Juan A Santamaria-Barria, Shan Zeng, Jonathan B Greer, Michael J Beckman, Adrian M Seifert, Noah A Cohen, Jennifer Q Zhang, Megan H Crawley, Benjamin L Green, Jennifer K Loo, Joanna H Maltbaek, Ronald P DeMatteo
Publikováno v:
PLoS ONE, Vol 14, Iss 5, p e0216275 (2019)
IntroductionMurine Kupffer cells (KCs) comprise CD11bhi and F4/80hi subsets. Tissue-resident macrophages are known to express the tyrosine kinase receptors colony-stimulating factor 1 receptor (Csf1r) and Mer. However, the expression of Csf1r and Mer
Externí odkaz:
https://doaj.org/article/a80dafa8cf094624998c32df6c766544
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Supplemental Figure 1.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::932eab0071328eca61301666575efc60
https://doi.org/10.1158/1078-0432.22651654.v1
https://doi.org/10.1158/1078-0432.22651654.v1
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Supplemental Figure 8.Relative MYLK mRNA expression by qPCR in GIST PDGFRA D842V PDXs treated with vehicle(Veh) or imatinib (IM) for 2 weeks.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::002022ffc6429b39d54180bdcfdbb0c7
https://doi.org/10.1158/1078-0432.22651630.v1
https://doi.org/10.1158/1078-0432.22651630.v1
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Supplemental Figure 3. GIST PDGFRA D842V PDXs are not sensitive to crenolanib.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::094b1bf9fdb23e92ce2a420e3025efa9
https://doi.org/10.1158/1078-0432.22651648.v1
https://doi.org/10.1158/1078-0432.22651648.v1
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Supplemental Figure 7.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::56c08442cbb17054a477469feca3c07d
https://doi.org/10.1158/1078-0432.22651633
https://doi.org/10.1158/1078-0432.22651633
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Supplemental Figure 4.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ac32aab5ac6d9413aa08a7989d9648cf
https://doi.org/10.1158/1078-0432.22651645.v1
https://doi.org/10.1158/1078-0432.22651645.v1
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Purpose:To create an in vivo model of PDGFRA D842V-mutant gastrointestinal stromal tumor (GIST) and identify the mechanism of tumor persistence following avapritinib therapy.Experimental Design:We created a patient-derived xenograft (PDX) of PDGFRA D
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::01aa5e516c830ea0ac7fc7bbac160e48
https://doi.org/10.1158/1078-0432.c.6604906
https://doi.org/10.1158/1078-0432.c.6604906
Autor:
Ronald P. DeMatteo, Jennifer Q. Zhang, Shan Zeng, Cristina R. Antonescu, Laura Wang, Kevin Do, Nesteene J. Param, Gerardo A. Vitiello, Andrew Hanna, Mark S. Etherington, Andrew Tieniber, Mengyuan Liu, Ferdinand Rossi
Supplemental Figure 6.Cell survival of GIST T1 cells treated with imatinib or avapritinib for 72h in complete media.Each data point represents an average of 10 wells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::196aa37791a5be757fbcf8160010722a
https://doi.org/10.1158/1078-0432.22651639.v1
https://doi.org/10.1158/1078-0432.22651639.v1
Autor:
Ronald P. DeMatteo, Cristina R. Antonescu, Peter Besmer, Joanna H. Maltbaek, Jennifer K. Loo, Megan H. Crawley, Ferdinand Rossi, Benjamin D. Medina, Michael J. Beckman, Noah A. Cohen, Juan A. Santamaria-Barria, Vinod P. Balachandran, Teresa S. Kim, Michael J. Cavnar, Jennifer Q. Zhang, Adrian M. Seifert, Shan Zeng
Figure S1. The relative mRNA expression of DKK4 and CTNNB1 in human KIT+ cells.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::52933a3c9bfd30a67aa4cbf8bcbbcda9
https://doi.org/10.1158/1535-7163.22508992
https://doi.org/10.1158/1535-7163.22508992