Zobrazeno 1 - 10
of 20
pro vyhledávání: '"Jennifer Polzer"'
Autor:
Felix Margenfeld, Adib Zendehdel, Giorgio Tamborrini, Jennifer Polzer, Marc Naville, Amélie Poilliot, Magdalena Müller-Gerbl
Publikováno v:
International Journal of Medical Students (2024)
Bursitis is a common condition in clinical practice, often causing pain in the shoulder and buttock areas due to inflamed bursae. Proper diagnosis and treatment depend on knowing the presence and exact location of these bursae. Anatomy classes typica
Externí odkaz:
https://doaj.org/article/22583cd8790a458bbe0a23a900e1ecf2
Autor:
Christian Vahlensieck, Cora S. Thiel, Daniel Pöschl, Timothy Bradley, Sonja Krammer, Beatrice Lauber, Jennifer Polzer, Oliver Ullrich
Publikováno v:
Frontiers in Cell and Developmental Biology, Vol 10 (2022)
The transcriptome of human immune cells rapidly reacts to altered gravity in a highly dynamic way. We could show in previous experiments that transcriptional patterns show profound adaption after seconds to minutes of altered gravity. To gain further
Externí odkaz:
https://doaj.org/article/781c6c4bf62c4bf89f39d7d79d18490c
Autor:
Christian Vahlensieck, Cora Sandra Thiel, Meret Mosimann, Timothy Bradley, Fabienne Caldana, Jennifer Polzer, Beatrice Astrid Lauber, Oliver Ullrich
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 2, p 1351 (2023)
Cellular effects of hypergravity have been described in many studies. We investigated the transcriptional dynamics in Jurkat T cells between 20 s and 60 min of 9 g hypergravity and characterized a highly dynamic biphasic time course of gene expressio
Externí odkaz:
https://doaj.org/article/47e10c2a97dd4dd2ba73358bc5485183
Autor:
Christian Vahlensieck, Cora Sandra Thiel, Swantje Christoffel, Sabrina Herbst, Jennifer Polzer, Beatrice Astrid Lauber, Saskia Wolter, Liliana Elisabeth Layer, Jochen Hinkelbein, Svantje Tauber, Oliver Ullrich
Publikováno v:
International Journal of Molecular Sciences, Vol 24, Iss 1, p 603 (2022)
The sensitivity of human immune system cells to gravity changes has been investigated in numerous studies. Human macrophages mediate innate and thus rapid immune defense on the one hand and activate T- and B-cell-based adaptive immune response on the
Externí odkaz:
https://doaj.org/article/9d0b962e0c204c90a127b010cb2ccf48
Rapid coupling between gravitational forces and the transcriptome in human myelomonocytic U937 cells
Autor:
Cora S. Thiel, Svantje Tauber, Swantje Christoffel, Andreas Huge, Beatrice A. Lauber, Jennifer Polzer, Katrin Paulsen, Hartwin Lier, Frank Engelmann, Burkhard Schmitz, Andreas Schütte, Christiane Raig, Liliana E. Layer, Oliver Ullrich
Publikováno v:
Scientific Reports, Vol 8, Iss 1, Pp 1-24 (2018)
Abstract The gravitational force has been constant throughout Earth’s evolutionary history. Since the cell nucleus is subjected to permanent forces induced by Earth’s gravity, we addressed the question, if gene expression homeostasis is constantl
Externí odkaz:
https://doaj.org/article/44e64d0c24c0444c8c368d6412db525b
Autor:
Christian Vahlensieck, Cora S. Thiel, Jan Adelmann, Beatrice A. Lauber, Jennifer Polzer, Oliver Ullrich
Publikováno v:
International Journal of Molecular Sciences, Vol 22, Iss 16, p 8451 (2021)
Cellular responses to micro- and hypergravity are rapid and complex and appear within the first few seconds of exposure. Transcriptomic analyses are a valuable tool to analyze these genome-wide cellular alterations. For a better understanding of the
Externí odkaz:
https://doaj.org/article/866098c1f24f4e94adf1f891e1863275
Autor:
Cora S. Thiel, Swantje Hauschild, Andreas Huge, Svantje Tauber, Beatrice A. Lauber, Jennifer Polzer, Katrin Paulsen, Hartwin Lier, Frank Engelmann, Burkhard Schmitz, Andreas Schütte, Liliana E. Layer, Oliver Ullrich
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-22 (2017)
Abstract We investigated the dynamics of immediate and initial gene expression response to different gravitational environments in human Jurkat T lymphocytic cells and compared expression profiles to identify potential gravity-regulated genes and ada
Externí odkaz:
https://doaj.org/article/cb286fb18e6c487984773382255761ca
Autor:
Cora Sandra Thiel, Swantje Christoffel, Svantje Tauber, Christian Vahlensieck, Diane de Zélicourt, Liliana E. Layer, Beatrice Lauber, Jennifer Polzer, Oliver Ullrich
Publikováno v:
International Journal of Molecular Sciences, Vol 21, Iss 2, p 514 (2020)
Cellular processes are influenced in many ways by changes in gravitational force. In previous studies, we were able to demonstrate, in various cellular systems and research platforms that reactions and adaptation processes occur very rapidly after th
Externí odkaz:
https://doaj.org/article/ad154f9e98ff4d38bd675fccc2263816
Autor:
Svantje Tauber, Beatrice A Lauber, Katrin Paulsen, Liliana E Layer, Martin Lehmann, Swantje Hauschild, Naomi R Shepherd, Jennifer Polzer, Jürgen Segerer, Cora S Thiel, Oliver Ullrich
Publikováno v:
PLoS ONE, Vol 12, Iss 4, p e0175599 (2017)
The immune system is one of the most affected systems of the human body during space flight. The cells of the immune system are exceptionally sensitive to microgravity. Thus, serious concerns arise, whether space flight associated weakening of the im
Externí odkaz:
https://doaj.org/article/5c08d3051302451196b975cebda28c39
Autor:
Cora Sandra Thiel, Svantje Tauber, Beatrice Lauber, Jennifer Polzer, Christian Seebacher, Rainer Uhl, Srujana Neelam, Ye Zhang, Howard Levine, Oliver Ullrich
Publikováno v:
International Journal of Molecular Sciences, Vol 20, Iss 10, p 2402 (2019)
The FLUMIAS (Fluorescence-Microscopic Analyses System for Life-Cell-Imaging in Space) confocal laser spinning disk fluorescence microscope represents a new imaging capability for live cell imaging experiments on suborbital ballistic rocket missions.
Externí odkaz:
https://doaj.org/article/0b9d97fa48774b4dbee89c6553ea28b3