Zobrazeno 1 - 10
of 14
pro vyhledávání: '"Jennifer Pierson"'
Publikováno v:
Frontiers in Toxicology, Vol 6 (2024)
Traditional approaches to preclinical drug safety assessment have generally protected human patients from unintended adverse effects. However, these assessments typically occur too late to make changes in the formulation or in phase 1 and beyond, are
Externí odkaz:
https://doaj.org/article/65edf2193e6245698c93414965eb96d2
Autor:
Laura D. Bertola, Anna Brüniche‐Olsen, Francine Kershaw, Isa‐Rita M. Russo, Anna J. MacDonald, Paul Sunnucks, Michael W. Bruford, Carlos Daniel Cadena, Kyle M. Ewart, Mark deBruyn, Mark D. B. Eldridge, Richard Frankham, Juan M. Guayasamin, Catherine E. Grueber, Thierry B. Hoareau, Sean Hoban, Paul A. Hohenlohe, Margaret E. Hunter, Antoinette Kotze, Josiah Kuja, Robert C. Lacy, Linda Laikre, Nathan Lo, Mariah H. Meek, Joachim Mergeay, Cinnamon Mittan‐Moreau, Linda E. Neaves, David O'Brien, Joel W. Ochieng, Rob Ogden, Pablo Orozco‐terWengel, Mónica Páez‐Vacas, Jennifer Pierson, Katherine Ralls, Robyn E. Shaw, Etotépé A. Sogbohossou, Adam Stow, Tammy Steeves, Cristiano Vernesi, Mrinalini Watsa, Gernot Segelbacher
Publikováno v:
Conservation Science and Practice, Vol 6, Iss 1, Pp n/a-n/a (2024)
Abstract Molecular tools are increasingly applied for assessing and monitoring biodiversity and informing conservation action. While recent developments in genetic and genomic methods provide greater sensitivity in analysis and the capacity to addres
Externí odkaz:
https://doaj.org/article/7a767005daf9469493148b626ea0bab6
Autor:
Ksenia Blinova, Qianyu Dang, Daniel Millard, Godfrey Smith, Jennifer Pierson, Liang Guo, Mathew Brock, Hua Rong Lu, Udo Kraushaar, Haoyu Zeng, Hong Shi, Xiaoyu Zhang, Kohei Sawada, Tomoharu Osada, Yasunari Kanda, Yuko Sekino, Li Pang, Tromondae K. Feaster, Ralf Kettenhofen, Norman Stockbridge, David G. Strauss, Gary Gintant
Publikováno v:
Cell Reports, Vol 24, Iss 13, Pp 3582-3592 (2018)
Summary: To assess the utility of human-induced pluripotent stem cell-derived cardiomyocytes (hiPSC-CMs) as an in vitro proarrhythmia model, we evaluated the concentration dependence and sources of variability of electrophysiologic responses to 28 dr
Externí odkaz:
https://doaj.org/article/3766b15437f1454ca223759395ad3b34
Ecological indicators and surrogates are used widely by resource managers to monitor and understand complex biota and ecosystem processes. Their potential to guide complex resource management has meant they have been proposed for use in all ecosystem
Publikováno v:
Journal of Visualized Experiments.
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::166c9694da286f4e05d4535367bfea29
https://doi.org/10.3791/64988
https://doi.org/10.3791/64988
Autor:
Ben C. Scheele, Renee L. Brawata, Emily P. Hoffmann, Rachael Loneragan, Sarah May, Jennifer Pierson, Jarrod D. Sopniewski, Brenton von Takach
Publikováno v:
Ecological Management & Restoration. 23:194-198
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::0087ea2bfcd23e88508e773650e467d6
https://doi.org/10.1111/emr.12554
https://doi.org/10.1111/emr.12554
Autor:
Stephanie J. Todd, Donald T. McKnight, Brad C. Congdon, Jennifer Pierson, Manuela Fischer, Sandra Abell, Jessica Koleck
Conservation translocations can restore populations and prevent extinction of threatened species. Sourcing adequate genetic diversity is an essential consideration when planning reintroductions, because it influences individual fitness and long-term
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::f66a97b6bd0ffad0b09dba135117a3ff
https://doi.org/10.21203/rs.3.rs-2262529/v1
https://doi.org/10.21203/rs.3.rs-2262529/v1
Publikováno v:
Conservation Genetics. 22:341-353
Reintroduction programs can benefit from optimisation of source populations to maximise genetic diversity. Here, we report an approach to guide genetic supplementation of founder individuals to maximise genetic diversity in a reintroduction program f
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::75dac83e406646ec460ffb037817cd8e
https://doi.org/10.1007/s10592-021-01341-6
https://doi.org/10.1007/s10592-021-01341-6
Autor:
Jean-Pierre Valentin, Peter Hoffmann, Catherine Ortemann-Renon, John Koerner, Jennifer Pierson, Gary Gintant, James Willard, Christine Garnett, Matthew Skinner, Hugo M Vargas, Todd Wisialowski, Michael K Pugsley
Publikováno v:
Toxicological sciences : an official journal of the Society of Toxicology. 187(1)
The content of this article derives from a Health and Environmental Sciences Institute (HESI) consortium with a focus to improve cardiac safety during drug development. A detailed literature review was conducted to evaluate the concordance between no
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::7c1bab76e6e11698e6ce6d673f29f20d
https://pubmed.ncbi.nlm.nih.gov/35148401
https://pubmed.ncbi.nlm.nih.gov/35148401
Autor:
Jennifer Pierson, Linda Laikre, Laura D. Bertola, Fred W. Allendorf, Per Sjögren-Gulve, Catherine E. Grueber, Sean Hoban, Rob Ogden, Antonio González-Rodríguez, Libby Liggins, Ivan Paz-Vinas, Michael William Bruford, Myriam Heuertz, W. Chris Funk, Gernot Segelbacher, Lisette P. Waits, Paul A. Hohenlohe, Margaret E. Hunter, Kerstin Johannesson, Gonzalo Gajardo, Nils Ryman, Martin F. Breed, David O'Brien, Farideh Moharrek, Clarisse Palma-Silva, Isa-Rita M. Russo, Philip W. Hedrick, Pablo Orozco-terWengel, Joachim Mergeay, Cristiano Vernesi, Anna J. MacDonald
Publikováno v:
Conservation Genetics. 22:537-539
A correction to this paper has been published: https://doi.org/10.1007/s10592-021-01376-9
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::083600558fb01b873175f7f1cf8ae4d0
https://doi.org/10.1007/s10592-021-01376-9
https://doi.org/10.1007/s10592-021-01376-9