Výsledky vyhledávání - "Jennifer Petovic"

Loss of dynamic regulation of G protein-coupled receptor kinase 2 by nitric oxide leads to cardiovascular dysfunction with aging

Autor: Rajika Roy, Ancai Yuan, Christopher J. Traynham, Erhe Gao, Konstantinos Drosatos, Gavin Landesberg, Steven J. Forrester, Claudio de Lucia, Douglas G. Tilley, Walter J. Koch, Jessica Pfleger, Jennifer Petovic, Michela Piedepalumbo, Matthew Hoffman, Rosario Scalia, Laurel A. Grisanti, Melissa Lieu, Satoru Eguchi

Publikováno v: American Journal of Physiology-Heart and Circulatory Physiology

Nitric oxide (NO) and S-nitrosothiol (SNO) are considered cardio- and vasoprotective substances. We now understand that one mechanism in which NO/SNOs provide cardiovascular protection is through their direct inhibition of cardiac G protein-coupled r

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::9943b5d2886fbe4556ca902d4895978e
https://pubmed.ncbi.nlm.nih.gov/32216616

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Abstract 841: Loss of S-nitrosylation of G Protein-Coupled Receptor Kinase 2 Leads to Cardiovascular Dysfunction With Aging

Autor: Steven J. Forrester, Christopher J. Traynham, Rosario Scalia, Gavin Landesberg, Satoru Eguchi, Erhe Gao, Walter J. Koch, Melissa Lieu, Jennifer Petovic

Publikováno v: Circulation Research. 125

Nitric oxide (NO) and S-nitrosothiol (SNO) have cardiovascular-protective properties and we have shown that one mechanism is through SNO-modification of G protein-coupled receptor (GPCR) kinase 2 (GRK2). S-nitrosylation at Cys340 (C340S) of GRK2 inhi

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::e44490f64afdb332dbc2f08358e22504
https://doi.org/10.1161/res.125.suppl_1.841

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Abstract 364: Cortical Bone Stem Cells Derived Exosomes as Potent Modulator of Cardiac Immune Response and Repair After Injury

Autor: Hajime Kubo, Steven R. Houser, Constantine D Troupes, Mohsin Khan, Jaslyn Johnson, Timothy Starosta, Yijun Yang, Sadia Mohsin, Jennifer Petovic, Remus M. Berretta

Publikováno v: Circulation Research. 119

Rationale: Cortical bone derived stem cells (CBSCs) are known to have improved growth kinetics and myocardial repair properties that are superior to other known stem cell types used. Salutary effects of CBSCs in large are mediated by paracrine secret

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::4660a57f7643f03f1fe17374c77de414
https://doi.org/10.1161/res.119.suppl_1.364

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