Zobrazeno 1 - 2
of 2
pro vyhledávání: '"Jennifer Percival-Alwyn"'
Autor:
Peter Thomas, Chloe Rees-Spear, Sarah Griffith, Luke Muir, Emma Touizer, Raiees Andrabi, Richard Priest, Jennifer Percival-Alwyn, Darryl Hayward, Amanda Buxton, William Traylen, Benny Chain, Trevor Wattam, Irene Sanjuan Nandin, Laura E. McCoy
Publikováno v:
iScience, Vol 27, Iss 4, Pp 109495- (2024)
Summary: Antigen-specific antibody infusion is known to enhance or suppress germinal center (GC) responses depending on the affinity of the infusion. We hypothesized that infusing monoclonal antibodies (mAbs) of escalating affinity during an immuniza
Externí odkaz:
https://doaj.org/article/0b1bcca32ac54979a20f34a6710b4940
Autor:
Darren J. Schofield, Jennifer Percival-Alwyn, Mateusz Rytelewski, John Hood, Raymond Rothstein, Leslie Wetzel, Kelly McGlinchey, Grace Adjei, Amanda Watkins, LeeAnn Machiesky, Weimin Chen, John Andrews, Maria Groves, Michelle Morrow, Ross A. Stewart, Andrew Leinster, Robert W. Wilkinson, Scott A. Hammond, Nadia Luheshi, Claire Dobson, Michael Oberst
Publikováno v:
mAbs, Vol 13, Iss 1 (2021)
Preclinical studies of PD-L1 and CTLA-4 blockade have relied heavily on mouse syngeneic tumor models with intact immune systems, which facilitate dissection of immunosuppressive mechanisms in the tumor microenvironment. Commercially developed monoclo
Externí odkaz:
https://doaj.org/article/5b7084f79f5a4c06ad3eff39bdaa115c