Zobrazeno 1 - 10
of 23
pro vyhledávání: '"Jennifer P. Gale"'
Publikováno v:
BMJ Open Sport & Exercise Medicine, Vol 10, Iss 3 (2024)
Objective To determine if performing regular 3-min bouts of resistance exercise spread over 4 hours in an evening will impact subsequent sleep quantity and quality, sedentary time and physical activity compared with prolonged uninterrupted sitting.Me
Externí odkaz:
https://doaj.org/article/e0f6f435f76542a8ab9e1aa5ad1aecad
Publikováno v:
Journal of Primary Health Care, Vol 12, Iss 1, Pp 79-87 (2020)
ABSTRACT INTRODUCTIONPractice nurses in general practice are ideally placed to deliver weight management treatments. Teaching people to eat according to their appetite, based on measurements of blood glucose (‘hunger training'), is known to lead to
Externí odkaz:
https://doaj.org/article/7ca009a951b745e7b165929cd174d4ed
Autor:
Yan-Ling Zhang, Sean P. Moran, Andrew Allen, David Baez-Nieto, Qihong Xu, Lei A. Wang, William E. Martenis, Joshua R. Sacher, Jennifer P. Gale, Michel Weïwer, Florence F. Wagner, Jen Q. Pan
Publikováno v:
ACS Pharmacology & Translational Science. 5:156-168
T-type voltage-gated Ca
Autor:
Mohammad H. Rohban, Ashley M. Fuller, Ceryl Tan, Jonathan T. Goldstein, Deepsing Syangtan, Amos Gutnick, Ann DeVine, Madhura P. Nijsure, Megan Rigby, Joshua R. Sacher, Steven M. Corsello, Grace B. Peppler, Marta Bogaczynska, Andrew Boghossian, Gabrielle E. Ciotti, Allison T. Hands, Aroonroj Mekareeya, Minh Doan, Jennifer P. Gale, Rik Derynck, Thomas Turbyville, Joel D. Boerckel, Shantanu Singh, Laura L. Kiessling, Thomas L. Schwarz, Xaralabos Varelas, Florence F. Wagner, Ran Kafri, T.S. Karin Eisinger-Mathason, Anne E. Carpenter
Identifying chemical regulators of biological pathways is currently a time-consuming bottleneck in developing therapeutics and small-molecule research tools. Typically, thousands to millions of candidate small molecules are tested in target-based bio
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::4fa998708d494bc5bb5f98affb1ae7d3
https://doi.org/10.1101/2021.07.29.454377
https://doi.org/10.1101/2021.07.29.454377
Autor:
Florence F. Wagner, Zhandong Liu, Kaifang Pang, Qihong Xu, Michael C. Lewis, Robia G. Pautler, Edward Holson, Blake Vuocolo, Theresa Estiphan, Jennifer P. Gale, Kihoon Han, Huda Y. Zoghbi, Jimmy Holder, Karen L. Eskow Jaunarajs, David G. Standaert, Michel Weïwer, Steen E. Pedersen, Wei Wang
While the contributions of some genes to neuropsychiatric disorders are clear, the downstream neuronal effects are poorly understood. Over-expression of SHANK3, which encodes a key synaptic protein, causes neuropsychiatric phenotypes in humans and ma
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::8e6ad87992a2f9f8a112d18e8b86b2a6
https://doi.org/10.21203/rs.3.rs-646721/v1
https://doi.org/10.21203/rs.3.rs-646721/v1
Autor:
Grazyna Joachimiak, Boguslaw Nocek, Lance Bigelow, Besnik Bajrami, Robert Jedrzejczak, Matthias Endres, Samantha Wellington, Stephen Johnston, Karolina Michalska, Stewart L. Fisher, Catherine Hatzos-Skintges, Deborah T. Hung, Changsoo Chang, Partha P. Nag, Andrzej Joachimiak, Jennifer P. Gale
Publikováno v:
IUCrJ, Vol 6, Iss 4, Pp 649-664 (2019)
IUCrJ
IUCrJ
The tryptophan synthases from three human pathogens show remarkable structural conservation, but at the same time display local differences in both their catalytic and allosteric sites that may be responsible for the observed differences in catalysis
Autor:
Eamon Comer, Joshua B. Radke, Herbert W. Virgin, L. David Sibley, Kimberly L. Carey, Stuart L. Schreiber, Jose Perez, Carol Mulrooney, Shailesh Metkar, Robert Hilgraf, Subrata Shaw, Jennifer P. Gale, Joshua A. Bittker
Publikováno v:
ACS Infectious Diseases. 4:1499-1507
Toxoplasma gondii is an obligate intracellular parasite capable of causing severe disease due to congenital infection and in patients with compromised immune systems. Control of infection is dependent on a robust Th1 type immune response including pr
Autor:
Stefan Steinbacher, Michel Weïwer, Surya A. Reis, Peter Müller, Peter Reinemer, Adrian Schomburg, Jennifer P. Gale, Daniel M. Fass, Stephen J. Haggarty, Krista M. Hennig, Edward B. Holson, Yan-Ling Zhang, Méryl Thomas, Florence F. Wagner, Stewart L. Fisher, Arthur J. Campbell, Wen-Ning Zhao, Martin R. Jefson
Publikováno v:
Bioorganic & Medicinal Chemistry. 24:4008-4015
The structure-activity and structure-kinetic relationships of a series of novel and selective ortho-aminoanilide inhibitors of histone deacetylases (HDACs) 1 and 2 are described. Different kinetic and thermodynamic selectivity profiles were obtained
Autor:
Florence F. Wagner, Deepika Walpita, Jennifer P. Gale, Noel G. Morgan, Bennett C. Meier, Shrikanta Chattopadhyay, Thomas Mandrup-Poulsen, Tamara J. Gilbert, Amedeo Vetere, Jacob M. Hooker, Taner Kaya, Mélanie Leroy, Sarah J. Richardson, Edward B. Holson, Yan-Ling Zhang, Morten Lundh, Stewart L. Fisher, Thomas Galbo, Patrick McCarren, Bridget K. Wagner, Dan Ploug Christensen
Publikováno v:
ACS Chemical Biology. 11:363-374
Modulation of histone deacetylase (HDAC) activity has been implicated as a potential therapeutic strategy for multiple diseases. However, it has been difficult to dissect the role of individual HDACs due to a lack of selective small-molecule inhibito
Autor:
Stuart L. Schreiber, Carol Mulrooney, Kimberly L. Carey, Robert Hilgraf, Joshua B. Radke, Subrata Shaw, Jose Perez, Shailesh Metkar, Eamon Comer, Joshua A. Bittker, Jennifer P. Gale, Herbert W. Virgin, L. David Sibley
Toxoplasma gondii is an obligate intracellular parasite capable of causing severe disease due to congenital infection and in patients with compromised immune systems. Control of infection is dependent on a robust Th1 type immune response including pr
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::712ed99facb8c160ca12dbdb5e16bf63
https://doi.org/10.1101/336818
https://doi.org/10.1101/336818