Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jennifer P. Borojerdi"'
Autor:
Mia Yu, Hannan M. Braun, Catherine C. Cooch, Emily Keller, Edward E. McKee, Jessica Ming, Irma L. Vazquez, Ofelia A. Olivero, Miriam C. Poirier, Jennifer P. Borojerdi
Publikováno v:
Toxicological Sciences
The antiretroviral efficacy of 3'-azido-3'-deoxythymidine (AZT) is dependent upon intracellular mono-, di-, and triphosphorylation and incorporation into DNA in place of thymidine. Thymidine kinase 1 (TK-1) catalyzes the first step of this pathway. M
Autor:
Catherine Cooch, Ofelia A. Olivero, Mia Yu, Jessica M. Ming, Jennifer P. Borojerdi, Barbara J. Taylor, Hannan M. Braun, Yvona Ward, Miriam C. Poirier, Cristina Semino-Mora
Publikováno v:
Mutation Research/Fundamental and Molecular Mechanisms of Mutagenesis. 665:67-74
The centrosome directs chromosomal migration by a complex process of tubulin-chromatin binding. In this contribution centrosomal abnormalities, including centrosomal amplification, were explored in Chinese hamster ovary (CHO) and normal human mammary
Autor:
Junji Tsurutani, Erin R. Gardner, Matthew Danish, Joell J. Gills, Jaclyn LoPiccolo, William D. Figg, M. Christine Hollander, Shigeru Kawabata, Maria Tsokos, Mones Abu-Asab, Patricia S. Steeg, Phillip A. Dennis, Noel A. Warfel, Robert H. Shoemaker, Jennifer P. Borojerdi, Carolyn J.M. Best
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 13(17)
Purpose: The development of new cancer drugs is slow and costly. HIV protease inhibitors are Food and Drug Administration approved for HIV patients. Because these drugs cause toxicities that can be associated with inhibition of Akt, an emerging targe
Autor:
Cristina Semino-Mora, Yvonna Ward, Jennifer P. Borojerdi, Miriam C. Poirier, Ofelia A. Olivero
Publikováno v:
Retrovirology, Vol 3, Iss Suppl 1, p P48 (2006)
Retrovirology
Retrovirology
The antiretroviral drug Zidovudine (AZT), a transplacental carcinogen in mice, becomes incorporated into DNA of eukaryotic cells and acts as a chain terminator. Previously we reported that NHMECs exposed to AZT exhibit S-phase arrest, alterations in