Zobrazeno 1 - 10
of 54
pro vyhledávání: '"Jennifer O. Manilay"'
Autor:
Janna M. Emery, Betsabel Chicana, Hanna Taglinao, Citlaly Ponce, Cristine Donham, Hawa Padmore, Aimy Sebastian, Scott L. Trasti, Jennifer O. Manilay
Publikováno v:
Frontiers in Hematology, Vol 2 (2024)
IntroductionErythropoiesis occurs in a specialized niche in the bone marrow and is regulated in part by oxygen-sensing signaling pathways. VHL is an E3 ubiquitin ligase that regulates the degradation of hypoxia-inducible factor (HIF) proteins under n
Externí odkaz:
https://doaj.org/article/4a49c124cf3840839390f0f8b623b95e
Autor:
Betsabel Chicana, Nastaran Abbasizadeh, Christian Burns, Hanna Taglinao, Joel A. Spencer, Jennifer O. Manilay
Publikováno v:
Frontiers in Immunology, Vol 13 (2022)
The contributions of skeletal cells to the processes of B cell development in the bone marrow (BM) have not been completely described. The von-Hippel Lindau protein (VHL) plays a key role in cellular responses to hypoxia. Previous work showed that Dm
Externí odkaz:
https://doaj.org/article/2fd8c79095e344f8af8d5b8706a0007c
Publikováno v:
Journal of Immunology Research, Vol 2016 (2016)
Understanding how embryonic stem cells and their derivatives interact with the adult host immune system is critical to developing their therapeutic potential. Murine embryonic stem cell-derived hematopoietic progenitors (ESHPs) were generated via coc
Externí odkaz:
https://doaj.org/article/b3fcfe1a78de4165bcb7ae5ed7457007
Autor:
Betsabel, Chicana, Nastaran, Abbasizadeh, Christian, Burns, Hanna, Taglinao, Joel A, Spencer, Jennifer O, Manilay
Publikováno v:
Frontiers in immunology. 13
The contributions of skeletal cells to the processes of B cell development in the bone marrow (BM) have not been completely described. The von-Hippel Lindau protein (VHL) plays a key role in cellular responses to hypoxia. Previous work showed that
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=pmid________::b188157e379c4692fe2b10c1245d6c26
https://pubmed.ncbi.nlm.nih.gov/35250971
https://pubmed.ncbi.nlm.nih.gov/35250971
Autor:
Christian Burns, Joel A. Spencer, Betsabel Chicana, Jennifer O. Manilay, Hanna Taglinao, Nastaran Abbasizadeh
The contributions of skeletal cells to the processes of B cell development in the bone marrow (BM) have not been completely described. The von-Hippel Lindau protein (VHL) plays a key role in cellular responses to hypoxia. Previous work showed thatDmp
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::b7dff991ee86be5fb9cc58b0719ea281
https://doi.org/10.1101/2021.09.10.459794
https://doi.org/10.1101/2021.09.10.459794
Autor:
Deepa K. Murugesh, Nicholas R. Hum, Cristine Donham, Alberto J. Millan, Sonny R. Elizaldi, Alexander G. Robling, Asmaa Mohamed, Aimy Sebastian, Michael Chi, Gabriela G. Loots, Jennifer O. Manilay, Brian Freeman, Betsabel Chicana
Publikováno v:
International journal of molecular sciences, vol 22, iss 17
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9111, p 9111 (2021)
International Journal of Molecular Sciences
Volume 22
Issue 17
International Journal of Molecular Sciences, Vol 22, Iss 9111, p 9111 (2021)
Romosozumab, a humanized monoclonal antibody specific for sclerostin (SOST), has been approved for treatment of postmenopausal women with osteoporosis at a high risk for fracture. Previous work in sclerostin global knockout (Sost−/−) mice indicat
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::d56498d00e8fed28c2cbd01f915b3321
https://escholarship.org/uc/item/1wc135k1
https://escholarship.org/uc/item/1wc135k1
Publikováno v:
Current osteoporosis reports, vol 17, iss 2
PURPOSE OF REVIEW: We reviewed the current literature on the roles of the Wnt antagonists sclerostin (Sost) and sclerostin-containing domain protein 1 (Sostdc1) on bone homeostasis, the relationship of the hypoxia-inducible factor (Hif) and von Hippe
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bdb820af7138631a0b1c31b4a3bb6161
https://doi.org/10.1007/s11914-019-00503-3
https://doi.org/10.1007/s11914-019-00503-3
Autor:
Asmaa Mohamed, Jennifer O. Manilay, Sonny R. Elizaldi, Alexander G. Robling, Brian Freeman, Alberto J. Millan, Betsabel Chicana, Gabriela G. Loots, Michael Chi, Deepa Murguesh, Cristine Donham
Romosozumab, a humanized monoclonal antibody specific for sclerostin, has been approved for treatment of post-menopausal women with osteoporosis at high risk for fracture. In several Phase III clinical trials, romosozumab decreased the risk of verteb
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::94b30b674a94236ed217cbb0bd3c64a4
https://doi.org/10.1101/2020.11.01.364158
https://doi.org/10.1101/2020.11.01.364158
Previous studies of NK cell inhibitory Ly49 receptors suggested their expression is stochastic. However, relatively few studies have examined this stochasticity in conjunction with activating Ly49 receptors. We hypothesized that the expression of act
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::a354f8b28f3c3a19d16a50172a5e4570
https://doi.org/10.1101/2020.05.23.112391
https://doi.org/10.1101/2020.05.23.112391
Autor:
Jennifer O. Manilay, Cristine Donham
Publikováno v:
Current osteoporosis reports, vol 18, iss 1
Purpose of reviewWe reviewed recent progress on the role of sclerostin (SOST) and its effects on the immune system in order to summarize the current state of knowledge in osteoimmunology, in regard to hematopoiesis, lymphopoiesis, and inflammation.Re
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::2505ee67a312dc5236b6534934082e5e
https://pubmed.ncbi.nlm.nih.gov/31970653
https://pubmed.ncbi.nlm.nih.gov/31970653