Výsledky vyhledávání - "Jennifer N. McAvoy"

Ska3 Is Required for Spindle Checkpoint Silencing and the Maintenance of Chromosome Cohesion in Mitosis

Autor: Tamara A. Potapova, Jonathan D. Wren, Jeremy J. Daniel, Jennifer N. McAvoy, Sushama Sivakumar, Gary J. Gorbsky, John R. Daum

Publikováno v: Current Biology. 19:1467-1472

Balanced chromosome segregation in mitosis requires synchronous chromatid separation at anaphase and the precise coordination of anaphase with cytokinesis and mitotic exit. The mitotic spindle checkpoint monitors proper attachment and/or tension indu

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::cc4fa4d4e6f770098662a32a0dc6b203
https://doi.org/10.1016/j.cub.2009.07.017

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Abstract 3868: Long-term inhibition of cells at metaphase with intact mitotic spindles results in unscheduled chromatid separation and catastrophic arrest in mitosis

Autor: John R. Daum, Gary J. Gorbsky, Tamara A. Potapova, Jennifer N. McAvoy, Jeremy J. Daniel, Sushama Sivakumar

Publikováno v: Cancer Research. 70:3868-3868

In the presence of unaligned chromosomes or other spindle abnormalities, the mitotic spindle checkpoint blocks both chromatid separation at anaphase and exit from mitosis. The spindle checkpoint is sustained by signaling from kinetochores that are no

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_________::8d9354a82d07d7e6e3c2fdafff2ea737
https://doi.org/10.1158/1538-7445.am10-3868

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