Výsledky vyhledávání - "Jennifer N. Hogan"

Data from The Aurora kinase inhibitor SNS-314 shows broad therapeutic potential with chemotherapeutics and synergy with microtubule-targeted agents in a colon carcinoma model

Autor: Raymond V. Fucini, W. Michael Flanagan, Marcus D. Ballinger, Jennifer N. Hogan, Pietro Taverna, Erica C. VanderPorten

Aurora kinases play key roles in regulating centrosome maturation, mitotic spindle formation, and cytokinesis during cell division, and are considered promising drug targets due to their frequent overexpression in a variety of human cancers. SNS-314

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::80cd91b6bb45f48f9401671f64046b18
https://doi.org/10.1158/1535-7163.c.6531854.v1

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Akademický článek

Housing and Demographic Risk Factors Impacting Foot and Musculoskeletal Health in African Elephants [Loxodonta africana] and Asian Elephants [Elephas maximus] in North American Zoos.

Autor: Michele A Miller, Jennifer N Hogan, Cheryl L Meehan

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0155223 (2016)

For more than three decades, foot and musculoskeletal conditions have been documented among both Asian [Elephas maximus] and African [Loxodonta africana] elephants in zoos. Although environmental factors have been hypothesized to play a contributing

Externí odkaz: https://doaj.org/article/983a72ae91c24438928be7adf9332245

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Akademický článek

Recumbence Behavior in Zoo Elephants: Determination of Patterns and Frequency of Recumbent Rest and Associated Environmental and Social Factors.

Autor: Matthew R Holdgate, Cheryl L Meehan, Jennifer N Hogan, Lance J Miller, Jeff Rushen, Anne Marie de Passillé, Joseph Soltis, Jeff Andrews, David J Shepherdson

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0153301 (2016)

Resting behaviors are an essential component of animal welfare but have received little attention in zoological research. African savanna elephant (Loxodonta africana) and Asian elephant (Elephas maximus) rest includes recumbent postures, but no larg

Externí odkaz: https://doaj.org/article/98c3e8e9c55341ada62227118b75f50a

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Akademický článek

Reproductive Health Assessment of Female Elephants in North American Zoos and Association of Husbandry Practices with Reproductive Dysfunction in African Elephants (Loxodonta africana).

Autor: Janine L Brown, Stephen Paris, Natalia A Prado-Oviedo, Cheryl L Meehan, Jennifer N Hogan, Kari A Morfeld, Kathy Carlstead

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0145673 (2016)

As part of a multi-institutional study of zoo elephant welfare, we evaluated female elephants managed by zoos accredited by the Association of Zoos and Aquariums and applied epidemiological methods to determine what factors in the zoo environment are

Externí odkaz: https://doaj.org/article/fea26dda13164303a6a6d8f7bb61c35e

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Akademický článek

Walking Behavior of Zoo Elephants: Associations between GPS-Measured Daily Walking Distances and Environmental Factors, Social Factors, and Welfare Indicators.

Autor: Matthew R Holdgate, Cheryl L Meehan, Jennifer N Hogan, Lance J Miller, Joseph Soltis, Jeff Andrews, David J Shepherdson

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0150331 (2016)

Research with humans and other animals suggests that walking benefits physical health. Perhaps because these links have been demonstrated in other species, it has been suggested that walking is important to elephant welfare, and that zoo elephant exh

Externí odkaz: https://doaj.org/article/38c78536084349e7a783e9b2bba46f0d

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Akademický článek

Housing and Social Environments of African (Loxodonta africana) and Asian (Elephas maximus) Elephants in North American Zoos.

Autor: Cheryl L Meehan, Jennifer N Hogan, Mary K Bonaparte-Saller, Joy A Mench

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0146703 (2016)

We evaluated 255 African (Loxodonta africana) and Asian (Elephas maximus) elephants living in 68 North American zoos over one year to quantify housing and social variables. All parameters were quantified for the both the day and the night and compari

Externí odkaz: https://doaj.org/article/2d826cf8c39d42b0a2b2ceaddf7a9223

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Akademický článek

Assessment of Body Condition in African (Loxodonta africana) and Asian (Elephas maximus) Elephants in North American Zoos and Management Practices Associated with High Body Condition Scores.

Autor: Kari A Morfeld, Cheryl L Meehan, Jennifer N Hogan, Janine L Brown

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0155146 (2016)

Obesity has a negative effect on health and welfare of many species, and has been speculated to be a problem for zoo elephants. To address this concern, we assessed the body condition of 240 elephants housed in North American zoos based on a set of s

Externí odkaz: https://doaj.org/article/4762205074084c21aa5efef3e343dc50

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Akademický článek

Determining Connections between the Daily Lives of Zoo Elephants and Their Welfare: An Epidemiological Approach.

Autor: Cheryl L Meehan, Joy A Mench, Kathy Carlstead, Jennifer N Hogan

Publikováno v: PLoS ONE, Vol 11, Iss 7, p e0158124 (2016)

Concerns about animal welfare increasingly shape people's views about the acceptability of keeping animals for food production, biomedical research, and in zoos. The field of animal welfare science has developed over the past 50 years as a method of

Externí odkaz: https://doaj.org/article/a08a405206b4490aafe76943ec25326c

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Estimating environmental conditions affecting protozoal pathogen removal in surface water wetland systems using a multi-scale, model-based approach

Autor: Melissa A. Miller, Patricia A. Conrad, Clare Dominik, Woutrina A. Smith, Jennifer N. Hogan, Miles E. Daniels, Karen Shapiro, Marc Los Huertos, Fred G.R. Watson, Stori C. Oates, Dane Hardin

Publikováno v: Science of The Total Environment. 493:1036-1046

Cryptosporidium parvum, Giardia lamblia, and Toxoplasma gondii are waterborne protozoal pathogens distributed worldwide and empirical evidence suggests that wetlands reduce the concentrations of these pathogens under certain environmental conditions.

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::05e3d736ce7734d488410af462568847
https://doi.org/10.1016/j.scitotenv.2014.06.053

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