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pro vyhledávání: '"Jennifer N. Earley"'
Autor:
Victor J. Anciano Granadillo, Jennifer N. Earley, Sarah C. Shuck, Millie M. Georgiadis, Richard W. Fitch, John J. Turchi
Publikováno v:
Journal of Nucleic Acids, Vol 2010 (2010)
Replication protein A (RPA) is the main eukaryotic single-strand (ss) DNA-binding protein involved in DNA replication and repair. We have identified and developed two classes of small molecule inhibitors (SMIs) that show in vitro inhibition of the RP
Externí odkaz:
https://doaj.org/article/105fba2e831342b5a65de6130732dac8
Autor:
Danielle A. Pfaff, Jennifer N. Earley, Karen A. Lewis, Sarah E. Altschuler, Deborah S. Wuttke
Publikováno v:
Nucleic Acids Research
Cdc13, the telomere end-binding protein from Saccharomyces cerevisiae, is a multidomain protein that specifically binds telomeric single-stranded DNA (ssDNA) with exquisitely high affinity to coordinate telomere maintenance. Recent structural and gen
Autor:
John J. Turchi, Jennifer N. Earley
Publikováno v:
Antioxidants & Redox Signaling. 14:2465-2477
DNA repair is essential for routine monitoring and repair of damage imparted to our genetic material by exposure to endogenous and exogenous carcinogens, including reactive oxygen species, UV light, and chemicals such as those found in cigarette smok
Autor:
Jennifer N. Earley, Andrew L. Zydney, Ki-Joo Sung, Matthew R. Micklin, Adith Venkiteshwaran, Shudipto K. Dishari
Publikováno v:
Biotechnology progress. 31(5)
Virus filtration can provide a robust method for removal of adventitious parvoviruses in the production of biotherapeutics. Although virus filtration is typically thought to function by a purely size-based removal mechanism, there is limited data in
Publikováno v:
Clinical cancer research : an official journal of the American Association for Cancer Research. 17(22)
A critical link exists between an individual's ability to repair cellular DNA damage and cancer development, progression, and response to therapy. Knowledge gained about the proteins involved and types of damage repaired by the individual DNA repair
Autor:
Jennifer N. Earley, Victor J. Anciano Granadillo, Richard W. Fitch, Sarah C. Shuck, John J. Turchi, Millie M. Georgiadis
Publikováno v:
Journal of Nucleic Acids
Journal of Nucleic Acids, Vol 2010 (2010)
Journal of Nucleic Acids, Vol 2010 (2010)
Replication protein A (RPA) is the main eukaryotic single-strand (ss) DNA-binding protein involved in DNA replication and repair. We have identified and developed two classes of small molecule inhibitors (SMIs) that showin vitroinhibition of the RPA-
Autor:
Jennifer N. Earley, John J. Turchi
Publikováno v:
Antioxidants & Redox Signaling; Jun2011, Vol. 14 Issue 12, p2465-2477, 13p