Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Jennifer N. Cha"'
Autor:
Shambojit Roy, Shane D. Curry, Conrad Corbella Bagot, Evan N. Mueller, Abdulrahman M. Mansouri, Wounjhang Park, Jennifer N. Cha, Andrew P. Goodwin
Publikováno v:
ACS Nano. 16:15873-15883
In this work, we demonstrate that a photo-cross-linkable conjugate of upconverting nanoparticles and cytosine deaminase can catalyze prodrug conversion specifically at tumor sites
Publikováno v:
ACS Biomaterials Science & Engineering.
Autor:
Evan N. Mueller, Talaial B. Alina, Shane D. Curry, Saheli Ganguly, Jennifer N. Cha, Andrew P. Goodwin
Publikováno v:
Journal of Materials Chemistry B. 10:9789-9793
Hydrophobically-modified silica-coated gold nanorods are presented here as multifunctional theranostic agents. A single modification both increases two-photon fluorescence and promotes cavitation-based acoustic signal for imaging. A two-fold greater
Autor:
Saheli Ganguly, Jennifer N. Cha, Andrew P. Goodwin, Marco A. Inzunza-Ibarra, Maju Kuriakose, Evan N. Mueller, Todd W. Murray, Ke Ma
Publikováno v:
ACS Applied Nano Materials. 4:12073-12082
Publikováno v:
Bioconjug Chem
The cell membrane possesses an extensive library of proteins, carbohydrates, and lipids that control a significant portion of inter- and intracellular functions, including signaling, proliferation, migration, and adhesion, among others. Augmenting th
Autor:
Albert Harguindey, Alexander W. Harris, Jennifer N. Cha, Omer Yehezkeli, Andrew P. Goodwin, Shambojit Roy, Ryan E. Patalano
Publikováno v:
ACS Applied Bio Materials. 3:1026-1035
We illustrate how intermolecular interactions facilitate ATP-free electron transfer between either native or engineered MoFe protein (MoFeP) from nitrogenase and a CdS nanorod (NR) by following the reduction of H
Autor:
Alexander W. Harris, Jennifer N. Cha
Publikováno v:
Molecular Systems Design & Engineering. 5:1088-1097
Understanding how proteins interface with synthetic nanomaterials has become increasingly important for a range of applications from nanomedicine to fuel generation. The nature of these bio-nano interactions is dynamic and specific to both the proper
Publikováno v:
Biomaterials science. 9(23)
3D culture is known to provide more faithful tissue models than 2D culture, and thus it is a valuable tool for in vitro evaluation of biological models. However, many cell lines are unable to form desired 3D spheroids by traditional methods because t
Autor:
Jennifer N. Cha, Michael G Bibbey
Publikováno v:
Virginia Journal of Business, Technology, and Science.
Nanomedicine is a rapidly advancing field as capabilities in nanoscale materials, devices, and sensing grow. Biocompatible nanoparticles have made their way into the pharmaceutical and biomedical market in imaging, diagnosis, targeted drug delivery,
Autor:
Alexander W. Harris, Jennifer N. Cha, Christopher N. Bowman, Albert Harguindey, Benjamin D. Fairbanks, Andrew P. Goodwin, Shambojit Roy
Publikováno v:
Biomacromolecules. 20:1683-1690
The simultaneous delivery of multiple therapeutics to a single site has shown promise for cancer targeting and treatment. However, because of the inherent differences in charge and size between drugs and biomolecules, new approaches are required for