Zobrazeno 1 - 10
of 119
pro vyhledávání: '"Jennifer N. Cha"'
Autor:
Shambojit Roy, Shane D. Curry, Conrad Corbella Bagot, Evan N. Mueller, Abdulrahman M. Mansouri, Wounjhang Park, Jennifer N. Cha, Andrew P. Goodwin
Publikováno v:
ACS Nano. 16:15873-15883
In this work, we demonstrate that a photo-cross-linkable conjugate of upconverting nanoparticles and cytosine deaminase can catalyze prodrug conversion specifically at tumor sites
Publikováno v:
ACS Biomaterials Science & Engineering.
Autor:
Evan N. Mueller, Talaial B. Alina, Shane D. Curry, Saheli Ganguly, Jennifer N. Cha, Andrew P. Goodwin
Publikováno v:
Journal of Materials Chemistry B. 10:9789-9793
Hydrophobically-modified silica-coated gold nanorods are presented here as multifunctional theranostic agents. A single modification both increases two-photon fluorescence and promotes cavitation-based acoustic signal for imaging. A two-fold greater
Autor:
Saheli Ganguly, Jennifer N. Cha, Andrew P. Goodwin, Marco A. Inzunza-Ibarra, Maju Kuriakose, Evan N. Mueller, Todd W. Murray, Ke Ma
Publikováno v:
ACS Applied Nano Materials. 4:12073-12082
Publikováno v:
Bioconjug Chem
The cell membrane possesses an extensive library of proteins, carbohydrates, and lipids that control a significant portion of inter- and intracellular functions, including signaling, proliferation, migration, and adhesion, among others. Augmenting th
Publikováno v:
Biomaterials science. 9(23)
3D culture is known to provide more faithful tissue models than 2D culture, and thus it is a valuable tool for in vitro evaluation of biological models. However, many cell lines are unable to form desired 3D spheroids by traditional methods because t
Autor:
Albert Harguindey, Alexander W. Harris, Jennifer N. Cha, Omer Yehezkeli, Andrew P. Goodwin, Shambojit Roy, Ryan E. Patalano
Publikováno v:
ACS Applied Bio Materials. 3:1026-1035
We illustrate how intermolecular interactions facilitate ATP-free electron transfer between either native or engineered MoFe protein (MoFeP) from nitrogenase and a CdS nanorod (NR) by following the reduction of H
Autor:
Alexander W. Harris, Jennifer N. Cha
Publikováno v:
Molecular Systems Design & Engineering. 5:1088-1097
Understanding how proteins interface with synthetic nanomaterials has become increasingly important for a range of applications from nanomedicine to fuel generation. The nature of these bio-nano interactions is dynamic and specific to both the proper
Autor:
Alexander W. Harris, Jennifer N. Cha, Christopher N. Bowman, Albert Harguindey, Benjamin D. Fairbanks, Andrew P. Goodwin, Shambojit Roy
Publikováno v:
Biomacromolecules. 20:1683-1690
The simultaneous delivery of multiple therapeutics to a single site has shown promise for cancer targeting and treatment. However, because of the inherent differences in charge and size between drugs and biomolecules, new approaches are required for
Autor:
Jennifer N. Cha, Michael G Bibbey
Publikováno v:
Virginia Journal of Business, Technology, and Science.
Nanomedicine is a rapidly advancing field as capabilities in nanoscale materials, devices, and sensing grow. Biocompatible nanoparticles have made their way into the pharmaceutical and biomedical market in imaging, diagnosis, targeted drug delivery,