Zobrazeno 1 - 10
of 18
pro vyhledávání: '"Jennifer N Sutton"'
Publikováno v:
PLoS ONE, Vol 7, Iss 8, p e42204 (2012)
The acquired enamel pellicle (AEP) is a thin film formed by the selective adsorption of salivary proteins onto the enamel surface of teeth. The AEP forms a critical interface between the mineral phase of teeth (hydroxyapatite) and the oral microbial
Externí odkaz:
https://doaj.org/article/e6116ef104914566bb8b5726f1b50e32
Autor:
Christina J. Vanhinsbergh, Angela Criscuolo, Jennifer N. Sutton, Keeley Murphy, Andrew J. K. Williamson, Ken Cook, Mark J. Dickman
Publikováno v:
Analytical Chemistry. 94:7339-7349
Large RNA including mRNA (mRNA) has emerged as an important new class of therapeutics. Recently, this has been demonstrated by two highly efficacious vaccines based on mRNA sequences encoding for a modified version of the SARS-CoV-2 spike protein. Th
Autor:
Florian Füssl, Jennifer N. Sutton, Silvia Millán-Martín, Ken Cook, Paul Gazis, Jonathan Bones, Sara Carillo, Kai Scheffler
Publikováno v:
European journal of pharmaceutics and biopharmaceutics : official journal of Arbeitsgemeinschaft fur Pharmazeutische Verfahrenstechnik e.V. 158
The biopharmaceutical industry continues to develop mAb-based biotherapeutics in increasing numbers. Due to their complexity, there are several critical quality attributes (CQAs) that need to be measured and controlled to guarantee product safety and
Autor:
Aaron O. Bailey, Wendy Sandoval, Jennifer N. Sutton, Jonathan L. Josephs, Guanghui Han, Wilson Phung, Paul Gazis
Publikováno v:
mAbs
The preponderance and diversity of charge variants in therapeutic monoclonal antibodies has implications for antibody efficacy and degradation. Understanding the extent and impact of minor antibody variants is of great interest, and it is also a crit
Autor:
Taha Rezai, David A. Sarracino, Scott Peterman, Ramesh Kuppusamy, Amol Prakash, Bryan Krastins, Michael Athanas, Mary F. Lopez, Jennifer N. Sutton, Kypros H. Nicolaides
Publikováno v:
Journal of Proteome Research. 10:133-142
The accurate diagnosis of Trisomy 21 requires invasive procedures that carry a risk of miscarriage. The current state-of-the-art maternal serum screening tests measure levels of PAPP-A, free bhCG, AFP, and uE3 in various combinations with a maximum s
Publikováno v:
Marine Chemistry. 95:183-198
Dissolved proteins in seawater samples from the Gulf of Mexico were concentrated using tangential flow ultrafiltration and methanol/chloroform/water precipitation. Following concentration and purification, two different separation methods were employ
Publikováno v:
Journal of Proteome Research. 3:1149-1154
A novel reversed-phase (RP-) HPLC gradient profile applicable to multidimensional separations of complex protein mixtures is reported. This gradient profile elutes small numbers of proteins from the RP-HPLC column in discrete intervals while minimizi
Autor:
Robert G. Harper, Aaron T. Timperman, Jennifer N. Sutton, Shayne Schuetzner, Sarah R. Workman
Publikováno v:
ELECTROPHORESIS. 25:1299-1306
Identification of the serum proteome is a daunting analytical task due to the complex nature of the sample which has an extremely large dynamic range of protein components. This report addresses this issue by using centrifugal ultrafiltration to enri
Autor:
Nena Bonn, Donald F. Hunt, Emily E. Baird, Audrey Seamons, Björn F.C. Kafsack, Craig Beeson, Dina L. Bai, Jeffrey Shabanowitz, Joan Goverman, Jennifer N. Sutton
Publikováno v:
The Journal of Experimental Medicine
Experimental allergic encephalomyelitis (EAE) is an animal model for multiple sclerosis induced by stimulating myelin basic protein (MBP)-specific T cells. The MBP-specific repertoire in B10.PL mice is shaped by tolerance mechanisms that eliminate MB
Autor:
Gouri Vadali, Johan Gobom, Lewis Couchman, Kaj Blennow, Jennifer N. Sutton, Mary F. Lopez, Vathany Kulasingam, Nabil G. Seidah, Caje Moniz, Urban A. Kiernan, Alejandra Garces, Randall W. Nelson, Eric E. Niederkofler, Joëlle R. Pérusse, Erik Portelius, Bruno Darbouret, Amol Prakash, Bryan Krastins, Scott Peterman, Dobrin Nedelkov, Josef Pannee, David A. Sarracino, Maryann Vogelsang, Benoit Coulombe, Gregory Byram
Publikováno v:
Clinical biochemistry. 46(6)
The aim of this study was to develop high-throughput, quantitative and highly selective mass spectrometric, targeted immunoassays for clinically important proteins in human plasma or serum.The described method coupled mass spectrometric immunoassay (