Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jennifer N, Kahn"'
Publikováno v:
Toxins, Vol 10, Iss 9, p 371 (2018)
Ricin A chain (RTA) depurinates the sarcin/ricin loop (SRL) by interacting with the C-termini of the ribosomal P stalk. The ribosome interaction site and the active site are located on opposite faces of RTA. The interaction with P proteins allows RTA
Externí odkaz:
https://doaj.org/article/1fba33bb2bae4dcea94f3bdf11c118e1
Publikováno v:
Toxins, Vol 10, Iss 6, p 240 (2018)
Ribosome-inactivating proteins (RIPs) are potent toxins that inactivate ribosomes by catalytically removing a specific adenine from the α-sarcin/ricin loop (SRL) of the large rRNA. Direct assays for measuring depurination activity and indirect assay
Externí odkaz:
https://doaj.org/article/343b30dca27b447d930d44c4c3f1ccf1
Publikováno v:
Scientific Reports, Vol 7, Iss 1, Pp 1-12 (2017)
Scientific Reports
Scientific Reports
Clostridium difficile is a significant concern as a nosocomial pathogen, and genetic tools are important when analyzing the physiology of such organisms so that the underlying physiology/pathogenesis of the organisms can be studied. Here, we used Tar
Publikováno v:
J Biol Chem
Ricin undergoes retrograde transport to the endoplasmic reticulum (ER), and ricin toxin A chain (RTA) enters the cytosol from the ER. Previous reports indicated that RTA inhibits activation of the unfolded protein response (UPR) in yeast and in mamma