Zobrazeno 1 - 4
of 4
pro vyhledávání: '"Jennifer Morawiak"'
Autor:
Abdelkader Seroutou, Yan Ji, Marios Giannakis, Margaret E. McLaughlin, David Smith, Elena Garralda, Filip Janku, Jennifer Morawiak, Ulka N. Vaishampayan, Roisin M. Connolly, Jason R. Dobson, Sinead Dolan, Guillem Argiles, Jordi Rodon, Susan Moody, Maja J.A. de Jonge
Publikováno v:
Cancer Research. 78:CT175-CT175
Background: Dysregulated Wnt/β-catenin signaling has been linked to several cancers, including pancreatic cancer (PC) and colorectal cancer (CRC). WNT974 (formerly LGK974) - a first-in-class, selective, oral inhibitor of Porcupine (an O-acyltransfer
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::80b7f4de129bb5703002843748ef0347
https://doi.org/10.1158/1538-7445.am2018-ct175
https://doi.org/10.1158/1538-7445.am2018-ct175
Autor:
Roisin M. Connolly, Guillem Argiles, Patricia LoRusso, Jennifer Morawiak, Jordi Rodon, Michael Palmer, Filip Janku, Yan Ji, Margaret E. McLaughlin, Andrea P. Myers, Maya de Jonge, Ulka N. Vaishampayan, Shu-Fang Hsu Schmitz
Publikováno v:
Molecular Cancer Therapeutics. 14:C45-C45
Background: Aberrant Wnt pathway activation is critical for initiation and maintenance of multiple tumor types, yet therapeutic inhibition of Wnt/β-catenin signaling has been challenged by the lack of tractable targets. WNT974 is an oral investigati
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::c344b275d54d4bca97665a6d971af381
https://doi.org/10.1158/1535-7163.targ-15-c45
https://doi.org/10.1158/1535-7163.targ-15-c45
Autor:
Sadhana Jain, Ping Li, Stephen Schmidt, Rebecca Roy, Linda Chee, Michael E. Bembenek, Thomas F. Parsons, Andrea Prack, Jennifer Morawiak
Publikováno v:
Assay and drug development technologies. 1(4)
We have characterized a recombinantly expressed N-terminally tagged GST fusion of the tyrosine kinase domain of human EphB3. The EphB3 kinase domain was shown to phosphorylate a group of synthetic tyrosine-containing peptides derived from a proprieta
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::e3079c4655f49671f6b3a6f5c1bcd029
https://pubmed.ncbi.nlm.nih.gov/15090252
https://pubmed.ncbi.nlm.nih.gov/15090252
Autor:
Michael E. Bembenek, Stephen Schmidt, Ping Li, Jennifer Morawiak, Andrea Prack, Sadhana Jain, Rebecca Roy, Thomas Parsons, Linda Chee
Publikováno v:
Assay & Drug Development Technologies; Aug2003, Vol. 1 Issue 4, p555-563, 9p