Zobrazeno 1 - 10
of 26
pro vyhledávání: '"Jennifer Meyers"'
Autor:
Nicole E. Skinner, Clinton O. Ogega, Nicole Frumento, Kaitlyn E. Clark, Harry Paul, Srinivasan Yegnasubramanian, Kornel Schuebel, Jennifer Meyers, Anuj Gupta, Sarah Wheelan, Andrea L. Cox, James E. Crowe, Stuart C. Ray, Justin R. Bailey
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
Externí odkaz:
https://doaj.org/article/924f0e1ce7a94d3cba312821ed1221c4
Autor:
Nicole E. Skinner, Clinton O. Ogega, Nicole Frumento, Kaitlyn E. Clark, Harry Paul, Srinivasan Yegnasubramanian, Kornel Schuebel, Jennifer Meyers, Anuj Gupta, Sarah Wheelan, Andrea L. Cox, James E. Crowe, Stuart C. Ray, Justin R. Bailey
Publikováno v:
Frontiers in Immunology, Vol 14 (2023)
IntroductionEarly development of broadly neutralizing antibodies (bNAbs) targeting the hepatitis C virus (HCV) envelope glycoprotein E2 is associated with spontaneous clearance of infection, so induction of bNAbs is a major goal of HCV vaccine develo
Externí odkaz:
https://doaj.org/article/83059043d7af474d8ff22e9b1d95b230
Autor:
Laura A. Sena, Rajendra Kumar, David E. Sanin, Elizabeth A. Thompson, D. Marc Rosen, Susan L. Dalrymple, Lizamma Antony, Yuhan Yang, Carolina Gomes-Alexandre, Jessica L. Hicks, Tracy Jones, Kiara A. Bowers, Jillian N. Eskra, Jennifer Meyers, Anuj Gupta, Alyza Skaist, Srinivasan Yegnasubramanian, Jun Luo, W. Nathaniel Brennen, Sushant K. Kachhap, Emmanuel S. Antonarakis, Angelo M. De Marzo, John T. Isaacs, Mark C. Markowski, Samuel R. Denmeade
Publikováno v:
The Journal of Clinical Investigation, Vol 132, Iss 23 (2022)
Testosterone is the canonical growth factor of prostate cancer but can paradoxically suppress its growth when present at supraphysiological levels. We have previously demonstrated that the cyclical administration of supraphysiological androgen (SPA),
Externí odkaz:
https://doaj.org/article/1190b8e3606d4217ab6c491c95462033
Autor:
Mindy K. Graham, Roshan Chikarmane, Rulin Wang, Ajay Vaghasia, Anuj Gupta, Qizhi Zheng, Bulouere Wodu, Xin Pan, Nicole Castagna, Jianyong Liu, Jennifer Meyers, Alyza Skaist, Sarah Wheelan, Brian W. Simons, Charles Bieberich, William G. Nelson, Theodore L. DeWeese, Angelo M. De Marzo, Srinivasan Yegnasubramanian
Publikováno v:
The Prostate. 83
Autor:
Carolina Gomes Alexandre, Jessica Hicks, Tracy Jones, John T Isaacs, Kiara Bowers, Alyza Skist, Laura Sena, Jennifer Meyers, Emmanuel Antonarakis, David Sanin, Hanfei Qi, Samuel Denmeade, Mark Markowski, Srinivasan Yegnasubramanian, Angelo De Marzo
Publikováno v:
Cancer Research. 83:4345-4345
While most patients with metastatic prostatic adenocarcinoma respond initially, nearly all develop resistance to multiple lines of androgen deprivation therapies. This is related to overexpression of the androgen receptor (AR), which is frequently dr
Autor:
Joel C. Sunshine, Tracee L. McMiller, Alyza Skaist, Yan Zhang, Alan Berger, Kornel Schuebel, Jennifer Meyers, Julie S. Deutsch, Aleksandra Ogurtsova, Elizabeth L. Engle, Leslie Cope, Janis M. Taube, Suzanne L. Topalian
Publikováno v:
Cancer Research. 83:2260-2260
Background: Neoadjuvant anti-PD-1-based therapies have shown promise in several cancers, including Merkel cell carcinoma (MCC), a rare and aggressive skin cancer. We have shown that on-treatment specimens from patients responding to anti-PD-1 are cha
Autor:
Laura A Sena, Rajendra Kumar, David E Sanin, Elizabeth A Thompson, D Marc Rosen, Susan L Dalrymple, Lizamma Antony, Yuhan Yang, Carolina Gomes-Alexandre, Jessica L Hicks, Tracy Jones, Kiara A. Bowers, Jillian N Eskra, Jennifer Meyers, Anuj Gupta, Alyza Skaist, Srinivasan Yegnasubramanian, Jun Luo, W Nathaniel Brennen, Sushant K Kachhap, Emmanuel S Antonarakis, Angelo M De Marzo, John T Isaacs, Mark C Markowski, Samuel R Denmeade
Testosterone is the canonical growth factor of prostate cancer but can paradoxically suppress its growth when present at supraphysiological levels. We have previously demonstrated that the cyclical administration of supraphysiological androgen (SPA),
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_________::d82b47707259bc746b90babc396b6619
https://doi.org/10.1101/2022.04.26.22274275
https://doi.org/10.1101/2022.04.26.22274275
Autor:
Mindy K Graham, Roshan Chikarmane, Rulin Wang, Ajay Vaghasia, Anuj Gupta, Qizhi Zheng, Bulouere Wodu, Xin Pan, Nicole Castagna, Jianyong Liu, Jennifer Meyers, Alyza Skaist, Sarah Wheelan, Brian W Simons, Charles Bieberich, William G Nelson, Theodore L DeWeese, Angelo M De Marzo, Srinivasan Yegnasubramanian
Evaluating the complex interplay of cell types in the tissue microenvironment is critical to understanding the origin and progression of diseases in the prostate and potential opportunities for intervention. Mouse models are an essential tool to inve
Externí odkaz:
https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b34876472691a77e09aef3721dcd1329
https://doi.org/10.1101/2022.01.31.478481
https://doi.org/10.1101/2022.01.31.478481
Autor:
Carolina Gomes Alexandre, Tracy Jones, Jessica L. Hicks, John T. Isaacs, Anuj Gupta, Alyza Skaist, Laura Sena, Jennifer Meyers, Emmanuel Antonarakis, Mark Markowski, Samuel Denmeade, Srinivasan Yegnasubramanian, Angelo Michael De Marzo
Publikováno v:
Cancer Research. 82:653-653
Molecular analysis of tissue samples from metastatic cancer lesions can improve our understanding of drug response and resistance. Since prostate cancer cells initially require androgen signaling through the androgen receptor (AR) for proliferation,
Autor:
Mark Christopher Markowski, Mary-Ellen Taplin, Rahul Raj Aggarwal, Laura Sena, Hao Wang, Aliya Lalji, Jennifer Meyers, Alyza Skaist, Anuj Gupta, Carolina Gomes-Alexandre, Tracy Jones, Jessica Hicks, Sushant Kachhap, Srinivasan Yegnasubramanian, Angelo M De Marzo, Samuel R. Denmeade, Emmanuel S. Antonarakis
Publikováno v:
Journal of Clinical Oncology. 40:5064-5064
5064 Background: During BAT, intramuscular (IM) administration of testosterone (T) results in rapid cycling of serum T from supraphysiologic to near-castrate levels in men with mCRPC. In a retrospective study, clinical responses to immune checkpoint