Výsledky vyhledávání - "Jennifer McKernan-Mullin"

Minority and majority pretreatment HIV-1 drug resistance associated with failure of first-line nonnucleoside reverse-transcriptase inhibitor antiretroviral therapy in Kenyan women

Autor: Thomas R Sibley, Lisa M. Frenkel, Jennifer McKernan-Mullin, Michael H. Chung, Wenjie Deng, James Kiarie, Samah R. Sakr, Rachel A Silverman, Robert W. Coombs, Ross S. Milne, Sandra Dross, Ingrid A. Beck

Publikováno v: AIDS

OBJECTIVES Among women initiating first-line nonnucleoside reverse-transcriptase inhibitor (NNRTI)-based-ART with and without a history of single-dose nevirapine (sdNVP) with or without zidovudine with or without lamivudine (ZDV with and without 3TC)

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::1f5b7224e9783f8e4a04ecc1c3cf2fe0
https://pubmed.ncbi.nlm.nih.gov/30946148

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Monotypic low-level HIV viremias during antiretroviral therapy are associated with disproportionate production of X4 virions and systemic immune activation

Autor: Kelli Kraft, Edward P. Acosta, Alberto La Rosa, Sarah Holte, Kevin J. Ryan, Sheila Styrchak, Jaime Soria, Corey A. Williams-Wietzikoski, Caroline M. Mitchell, Marta E. Bull, Eduardo Ticona, Jillian Legard, Lisa M. Frenkel, Jennifer McKernan-Mullin, Joshua E. Stern, Robert W. Coombs, Frankline Onchiri

Publikováno v: AIDS (London, England)

Objective: During effective antiretroviral therapy (ART), low-level plasma viremias (LLV) (HIV RNA >30–1000 copies/ml) can be detected intermittently. We hypothesized that systemic inflammation is associated with LLV either as the cause or result o

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::84009a5756f76b1f4ab5c9382d053c78
https://pubmed.ncbi.nlm.nih.gov/29683841

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Human Immunodeficiency Viruses Appear Compartmentalized to the Female Genital Tract in Cross-Sectional Analyses but Genital Lineages Do Not Persist Over Time

Autor: Lisa M. Frenkel, Robert W. Coombs, Jennifer McKernan-Mullin, Kelli Kraft, Laura Heath, Jane Hitti, Susan E. Cohn, Marta E. Bull, Luis Acevedo, Sarah Holte, James I. Mullins, Kenneth Tapia, Joan Dragavon

Publikováno v: The Journal of Infectious Diseases. 207:1206-1215

Whether human immunodeficiency virus (HIV) in the female genital tract constitutes a genetically distinct compartment from the blood remains an important question, with both clinical and biologic implications because of the role of the genital tract

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::bce4c0cbbe062ce38784ccac99cb5395
https://doi.org/10.1093/infdis/jit016

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Interaction Between Lactobacilli, Bacterial Vaginosis-Associated Bacteria, and HIV Type 1 RNA and DNA Genital Shedding in U.S. and Kenyan Women

Autor: Jane Hitti, Caroline M. Mitchell, Craig R. Cohen, Susan E. Cohn, Lisa M. Frenkel, David N. Fredricks, Amneris E. Luque, Jennifer McKernan-Mullin, Robert W. Coombs, Christina Mwachari, Jennifer E. Balkus, Congzhou Liu

Publikováno v: AIDS Research and Human Retroviruses. 29:13-19

Bacterial vaginosis has been associated with genital HIV-1 shedding; however, the effect of specific vaginal bacterial species has not been assessed. We tested cervicovaginal lavage from HIV-1-seropositive women for common Lactobacillus species: L. c

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::4a1865ba5c9b9cd0a3cfd4663e9c21ac
https://doi.org/10.1089/aid.2012.0187

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Increasing HIV-1 Pre-Treatment Drug Resistance among Antiretroviral-Naïve Adults Initiating Treatment between 2006 and 2014 in Nairobi, Kenya

Autor: James Kiarie, Joshua E. Stern, Sandra Dross, Kenneth Tapia, Samah R. Sakr, Bhavna Chohan, Ingrid A. Beck, Rachel A Silverman, Lisa M. Frenkel, Nelly Yatich, Jennifer McKernan-Mullin, Michael H. Chung, Stephen Bii

Antiretroviral-naïve adults initiating antiretroviral therapy (ART) in Nairobi, Kenya were tested for HIV-1 drug resistance at codons K103N, Y181C, G190A, M184V, and K65R using an oligonucleotide ligation assay (OLA). Prevalence of pre-treatment dru

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::b74990ef63daf2672257c1b8b8930785
https://europepmc.org/articles/PMC4889515/

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Monitoring of HIV Type 1 DNA Load and Drug Resistance in Peripheral Blood Mononuclear Cells During Suppressive Antiretroviral Therapy Does Not Predict Virologic Failure

Autor: Ingrid A. Beck, Lisa M. Frenkel, Jennifer McKernan-Mullin, Paul Krogstad, Minyoung Jang, Sharon Nachman, Marta E. Bull, Susan H. Eshleman, Sharon Huang, Andrew Wiznia, Lin Ye Song, Thor A. Wagner

Publikováno v: AIDS Research and Human Retroviruses. 28:780-788

Our objective was to determine whether monitoring HIV-1 DNA concentration or new resistance mutations in peripheral blood mononuclear cells (PBMCs) during effective antiretroviral therapy (ART) predicts virologic failure. A retrospective analysis use

Externí odkaz: https://explore.openaire.eu/search/publication?articleId=doi_dedup___::ab1861753ab38b42fb460d73e486b9f1
https://doi.org/10.1089/aid.2011.0039

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