Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid – method comparison and round robin study

Autor: Erik Stoops, Brit Mollenhauer, Hugo Vanderstichele, Jing Zhang, Charlotte E. Teunissen, Henrik Zetterberg, Niels Kruse, Adrian W. Schmid, Kuldip D. Dave, Leslie M. Shaw, Jill Dunty, Robert M. Umek, Frederick Du Bois Bowman, Samantha J. Hutten, Tanja Schubert, Kaj Blennow, Marc Moniatte, Omar M. A. El-Agnaf, Daniel Drake, Chris L. Smith, Jennifer Masucci, Peggy Taylor, Hilal A. Lashuel, Jimmy Duong

Publikováno v: Journal of Neurochemistry
Journal of Neurochemistry, 149(1), 126-138. Wiley-Blackwell
Mollenhauer, B, Bowman, F D, Drake, D, Duong, J, Blennow, K, el-Agnaf, O, Shaw, L M, Masucci, J, Taylor, P, Umek, R M, Dunty, J M, Smith, C L, Stoops, E, Vanderstichele, H, Schmid, A W, Moniatte, M, Zhang, J, Kruse, N, Lashuel, H A, Teunissen, C, Schubert, T, Dave, K D, Hutten, S J & Zetterberg, H 2019, ' Antibody-based methods for the measurement of α-synuclein concentration in human cerebrospinal fluid – method comparison and round robin study ', Journal of Neurochemistry, vol. 149, no. 1, pp. 126-138 . https://doi.org/10.1111/jnc.14569

α-Synuclein is the major component of Lewy bodies and a candidate biomarker for neurodegenerative diseases in which Lewy bodies are common, including Parkinson's disease and dementia with Lewy bodies. A large body of literature suggests that these d

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